A5002443900- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- COVID-19 Clinical Research Studies
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Long-Term Effects of COVID-19
- Lung Cancer Research Studies
- COVID-19 diagnosis using AI
- Medical Imaging Techniques and Applications
- Pleural and Pulmonary Diseases
- SARS-CoV-2 and COVID-19 Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer Genomics and Diagnostics
- Musculoskeletal synovial abnormalities and treatments
- MRI in cancer diagnosis
- Advanced biosensing and bioanalysis techniques
- Atomic and Subatomic Physics Research
- Muscle and Compartmental Disorders
- Pituitary Gland Disorders and Treatments
- Myasthenia Gravis and Thymoma
- Cardiac Arrhythmias and Treatments
- Cardiac tumors and thrombi
- Acute Ischemic Stroke Management
- Hematological disorders and diagnostics
- Gout, Hyperuricemia, Uric Acid
Zhongnan Hospital of Wuhan University
2015-2024
Wuhan University
2015-2024
Hunan Academy of Traditional Chinese Medicine
2024
Shenzhen Bao'an District People's Hospital
2022
University of Chicago
2020
ORCID
2020
Albany Medical Center Hospital
2015
Polytechnic University of Turin
2014
Politecnico di Milano
2014
SP Technology (South Korea)
2014
Data on pathologic changes of the 2019 novel coronavirus disease (COVID-19) are scarce. To gain knowledge about pathology that may contribute to progression and fatality, we performed post-mortem needle core biopsies lung, liver, heart in four patients who died COVID-19 pneumonia. The patients’ ages ranged from 59 81, including 3 males 1 female. Each patient had at least one underlying disease, immunocompromised status (chronic lymphocytic leukemia renal transplantation) or other...
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Purpose To compare radiologic characteristics of coronavirus disease 2019 (COVID-19) pneumonia at thin-section CT on admission between patients with mild and severe disease. Materials Methods Seventy COVID-19 who were admitted to Zhongnan Hospital Wuhan University January 20, 2020 27, enrolled. On the basis World Health Organization guidelines, 50 categorized form 20 based clinical conditions. Imaging features, clinical, laboratory data reviewed compared. Results Patients (median age, 65...
PCR-based techniques routinely employed for the detection of mutated linear DNA molecules, including circulating tumor (ctDNA), require large nucleotide sections on both sides mutation primer annealing. This means that fragments with a positioned closer to extremities are unlikely be detected. Thus, sensors capable recognizing characteristic mutations ends would advantageous over state-of-the-art approaches. Here, an electrochemiluminescence-resonance energy transfer (ECL-RET) biosensor...
Abstract Background Several reports on epidemiological and clinical features of the 2019 coronavirus disease (COVID-19) have been published. However, mortality morbidity analyses, important for better understanding pathogenesis this disease, are scarce. We examine laboratory 14 patients who died COVID-19. Methods The cohort consisted 11 male 3 female patients, with 9 aged 70 years or above, nearly all had underlying diseases. Results Fever bilateral pneumonia was main manifestation. Most...
Accurate diagnosis of N2 lymph node status the resectable stage I-II non-small cell lung cancer (NSCLC) before surgery is crucial, while there lack corresponding method clinically.To develop and validate a model to quantitively predict metastasis in presurgical clinical NSCLC using multiview radiomics deep learning method.In this study, 140 patients were enrolled randomly divided into training test sets. Univariate multiple analysis used step by establish model; Then modeling scheme was...
Purpose: To compare the diagnostic accuracy and safety of computed tomography (CT)-guided core needle biopsy (CNB) between pulmonary ground-glass solid nodules using propensity score matching (PSM) method determine relevant risk factors. Methods: This was a single-center retrospective cohort study data from 665 patients who underwent CT-guided CNB in our hospital May 2019 2021, including 39 (GGNs) 626 nodules. We used 1:4 PSM analysis to compared yields complications rates 2 groups. Results:...
Background Discrepancies still exist in the diagnosis of primary pulmonary cryptococcosis immunocompetent patients. Purpose To describe and evaluate radiological manifestations Material Methods Twenty-six histopathologically confirmed cases were analyzed for clinical, pathological, CT characteristics. Necessary statistical tests differences presentations correlation analysis between clinical characteristics performed. Results The patients' ages ranged from 24 to 79 years, with 20 men six...
Abstract Background To the best of our knowledge, muscle soreness is a common manifestation for coronavirus disease-19 (COVID-19) patients, but mechanism severe acute respiratory syndrome 2 (SARS-CoV-2) injury to skeletal remains unclear, there has been no publication focused on involvement in COVID-19 patients. Case presentation We present case two Chinese men with COVID-19, whose symptoms were fatigue and soreness. They went through different treatments, patient 1, 81-year-old, eventually...
A liquid biopsy is a noninvasive approach for detecting double-stranded circulating tumor DNA (ctDNA) of 90-320 nucleotides in blood plasma from patients with cancer. Most techniques employed ctDNA detection are time consuming and require expensive purification kits. Electrochemiluminescence resonance energy transfer (ECL-RET) biosensors exhibit high sensitivity, wide response range, promising straightforward sensing applications. Until now, ECL-RET have been designed short single-stranded...
Background: Lung cancer histologic types and subtypes are closely associated with treatment selection prognosis prediction. In this study, we aim to evaluate the suitability of computed tomography-guided percutaneous core needle biopsy (CT-guided PCNB) in typing subtyping lung cancer. Methods: From August 2007 December 2015, patients who underwent CT-guided PCNB lesion resection were retrospectively collected analyzed. All pathological sections reassessed consensus by 2 junior pathologists...
To explore the relationship between computed tomography (CT) manifestations of thymoma and its WHO pathological classification.One hundred five histopathologically confirmed cases were collected for their CT characteristics results statistically compared different types thymoma.Tumor size, shape, necrosis or cystic change, capsule integrity, invasion to adjacent tissue, lymphadenopathy, presence pleural effusion significantly thymomas (P<0.05). Type B2, B3 tumors thymic carcinomas greater in...