A5017583744- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Ferrocene Chemistry and Applications
- Protein Interaction Studies and Fluorescence Analysis
- Crystallography and molecular interactions
- Synthesis and Biological Evaluation
- Crystal structures of chemical compounds
- Organometallic Compounds Synthesis and Characterization
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis of Tetrazole Derivatives
- DNA and Nucleic Acid Chemistry
- Synthesis and biological activity
- Trace Elements in Health
- Click Chemistry and Applications
- Phenothiazines and Benzothiazines Synthesis and Activities
- Antimicrobial agents and applications
- Milk Quality and Mastitis in Dairy Cows
- Thermal and Kinetic Analysis
- Photosynthetic Processes and Mechanisms
- Biological Stains and Phytochemicals
- Biopolymer Synthesis and Applications
- Microbial Metabolism and Applications
- Essential Oils and Antimicrobial Activity
- Inorganic and Organometallic Chemistry
University of Kragujevac
2018-2025
A chloride salt of the tetrameric gold(III) complex with L-valyl-L-histidine dipeptide (L-Val-L-His), [Au(L-Val-L-His)]4Cl2·14.5H2O, was obtained from mononuclear [Au(L-Val-L-His)Cl]Cl·2H2O species at pH 7.00 in aqueous solution room temperature. The characterized by 1H NMR and IR spectroscopic techniques, while its structure determined single-crystal X-ray diffraction analysis. In title compound, each ion is coordinated three nitrogen atoms, as corresponding (amine NA, deprotonated amide...
Dimethyl 6-(pyrazine-2-yl)pyridine-3,4-dicarboxylate (py-2pz) was used as a ligand for the synthesis of new copper(ii) and silver(i) complexes, [CuCl2(py-2pz)]2 (1), [Cu(CF3SO3)(H2O)(py-2pz)2]CF3SO3·2H2O (2), [Ag(py-2pz)2]PF6 (3) {[Ag(NO3)(py-2pz)]·0.5H2O} n (4). The complexes were characterized by spectroscopic electrochemical methods, while their structures determined single crystal X-ray diffraction analysis. analysis revealed bidentate coordination mode py-2pz to corresponding metal ion...
The negative environmental and social impacts of food waste accumulation can be mitigated by utilizing bio-refineries' approach where is revalorized into high-value products, such as prodigiosin (PG), using microbial bioprocesses. diverse biological activities PG position it a promising compound, but its high production cost promiscuous bioactivity hinder wide application. Metal ions modulate the electronic properties organic molecules, leading to novel mechanisms action increased target...
Silver(<sc>i</sc>) complexes with pyridine-4,5-dicarboxylates show significant activity against clinical isolates from the milk of a cow diagnosed mastitis.
Three new silver(I) complexes [Ag(NO3)(tia)(H2O)]n (Ag1), [Ag(CF3SO3)(1,8-naph)]n (Ag2) and [Ag2(1,8-naph)2(H2O)1.2](PF6)2 (Ag3), where tia is thianthrene 1,8-naph 1,8-naphthyridine, were synthesized structurally characterized by different spectroscopic electrochemical methods their crystal structures determined single-crystal X-ray diffraction analysis. Their antimicrobial potential was evaluated against four bacterial three Candida species, the obtained results revealed that these showed...
Five novel copper(ii) complexes with pyridine-4,5-dicarboxylate esters as ligands, [Cu(NO3)(py-2tz)(H2O)3]NO3 (1), [Cu(NO3)2(py-2metz)(H2O)] (2), [Cu(NO3)2(py-2py)(H2O)]·H2O (3), [CuCl2(py-2tz)]2 (4) and [CuCl2(py-2metz)]n (5) (py-2tz is dimethyl 2-(thiazol-2-yl)pyridine-4,5-dicarboxylate, py-2metz 2-(4-methylthiazol-2-yl)pyridine-4,5-dicarboxylate py-2py 2,2'-bipyridine-4,5-dicarboxylate), were synthesized structurally characterized by different spectroscopic electrochemical methods. The...
1,2-Bis(4-pyridyl)ethane (bpa) and 1,2-bis(4-pyridyl)ethene (bpe) were used for the synthesis of polynuclear silver(I) complexes, {[Ag(bpa)]NO 3 } n ( 1 ), {[Ag(bpa) 2 ]CF SO . H O} ) {[Ag(bpe)]CF ). In complexes 1–3 , corresponding nitrogen-containing heterocycle acts as a bridging ligand between two Ag(I) ions. vitro antimicrobial activity these along with ligands their synthesis, was evaluated against broad panel Gram-positive Gram-negative bacteria fungi. The showed selectivity towards...
Two zinc(II) complexes with dimethyl 2,2′-bipyridine-4,5-dicarboxylate (py-2py) of the general formula [Zn(py-2py)X2], X = Cl− (1) and Br− (2) were synthesized characterized by NMR, IR UV-Vis spectroscopy single-crystal X-ray diffraction analysis. Complexes 1 2 are isostructural adopt a slightly distorted tetrahedral geometry values indices τ4 τ’4 in range 0.80–0.85. The evaluated for their vitro antimicrobial activity against two bacterial (Pseudomonas aeruginosa Staphylococcus aureus)...
Gold complexes have been traditionally employed in medicine, and currently, some gold(I) complexes, such as auranofin, are clinically used the treatment of rheumatoid arthritis. In last decades, both gold(III) with different types ligands gained considerable attention potential antitumor agents, showing superior activity vitro vivo to agents. The present review article summarizes results achieved field synthesis evaluation gold amino acids peptides moieties for their cytotoxicity. first...
In the present study, a zinc(II) complex with 4-ethynyl-2,2?-bipyridine (ebpy), [Zn(ebpy)Cl2], was synthesized and characterized by spectroscopic (1H-NMR, IR UV?Vis) methods molar conductivity measurement. The crystal structure of [Zn(ebpy)Cl2] determined single-crystal X-ray diffraction analysis, confirming bidentate coordination ebpy ligand through its two nitrogen atoms, while remaining sites are occupied chloride ions. With aim to investigate reactivity toward biologically important...
Polynuclear silver(I) complex, [Ag(NO3-O)(2,2'-bq-N,N')]n, was synthesized by the reaction of equimolar amount nitrate and 2,2'-biquinoline (2,2'-bq) in ethanol at room temperature. The characterization complex established on basis elemental microanalysis, IR, NMR (1H 13C) UV-Vis spectroscopic techniques. results analyses revealed that [Ag(NO3-O)(2,2'-bq-N,N')]n 2,2'-bq ligand behaves as a chelate, while remaining coordination sites are occupied oxygen atoms two nitrates.
New silver(I) complex with thianthrene (tia), [Ag(NO3)(tia)(H2O)]n, was synthesized by the reaction of AgNO3 an equimolar amount tia in ethanol/dichloromethane (v/v 1:1) at room temperature, and characterized NMR, IR UV-Vis spectroscopy single-crystal X-ray diffraction analysis. The antimicrobial activity evaluated against broad panel Gram-positive Gram-negative bacteria Candida spp. This showed significant toward important human pathogens Staphylococcus aureus parapsilosis minimal...
Silver(I) compounds are well known for their pharmacological applications as antibiotics and have been also evaluated potential anticancer agents. The use of simple silver(I) salts, such AgNO3, an antimicrobial agent, has limited due to the formation AgCl precipitate under physiological conditions, preventing a major part Ag(I) ions reach infected site. On other hand, slow maintainable release ion into cell or tissue could be achieved by its administration in form complexes. Among different...
The present study reports the synthesis and spectroscopic characterization of dinuclear silver(I) complexes, {[Ag(X-O)(phtz-N)]2(µ-phtz-N,N')2} (X = NO3 - (Ag1) CF3SO3 (Ag2), phtz is phthalazine). interaction these two complexes with calf thymus DNA (ct-DNA) bovine serum albumin (BSA) was investigated to assess their binding affinity biomolecules. constants Ag1 Ag2 BSA are found be higher than those for ct-DNA, being in accordance toward studied protein. values partition coefficient (logP)...