- Lower Extremity Biomechanics and Pathologies
- Muscle activation and electromyography studies
- EEG and Brain-Computer Interfaces
- Stroke Rehabilitation and Recovery
- Neurological Disease Mechanisms and Treatments
- Ovarian function and disorders
- Mechanical Engineering and Vibrations Research
- Lipid metabolism and disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Physical Activity and Health
- Total Knee Arthroplasty Outcomes
- Liver Disease Diagnosis and Treatment
- Bone fractures and treatments
- Nutrition and Health in Aging
- Neuroinflammation and Neurodegeneration Mechanisms
- Diet, Metabolism, and Disease
- Neonatal and fetal brain pathology
- S100 Proteins and Annexins
- Inflammation biomarkers and pathways
- Obesity, Physical Activity, Diet
- Diabetic Foot Ulcer Assessment and Management
- Medicinal Plants and Neuroprotection
- Advanced Sensor and Energy Harvesting Materials
- Orthopedic Surgery and Rehabilitation
- Neurological Disorders and Treatments
Nanjing Medical University
2012-2025
Jiangsu Province Hospital
2012-2025
Changsha University of Science and Technology
2021
China Pharmaceutical University
2019
Triggering receptor expressed in myeloid cells (TREM)2 is a genetic high-risk factor for sporadic Alzheimer's disease (AD) and considered potential target AD diagnosis therapy, although its role the different stages of remains controversial. We generated an embryonic deletion Trem2 (whole body deletion) induced hippocampa1- cortical-specific knockdown microglial at process amyloid precursor protein/Psen1 mice by adeno-associated virus (AAV) infection. AAV infection overexpression hippocampus...
Abstract Purpose To investigate how steroid receptor RNA activator (SRA) regulates follicular development in mice. Methods Systemic SRA knockout mice were introduced. expression was reinstated the anteroventral periventricular nucleus (AVPV) of hypothalamus using lentiviral vectors. Subsequently, estrous cycle, serum hormone levels, follicle development, and hypothalamic kisspeptin assessed. Kiss1 promoter activity tested with a fluorescent reporter system Neuro-2a cells. Results deficiency...
Abstract We investigated the effects of chrysin (CHR) on nonalcoholic fatty liver disease (NAFLD) in mice. The NAFLD mouse model was established using a diet deficient methionine and choline (MCD). CHR shown to attenuate MCD‐induced hepatic fat accumulation, increase very low‐density lipoprotein (VLDL) secretion, decrease oxidative stress Inhibition or direct suppression protein kinase C (PKC) by significantly reduced PKC activity liver, leading inhibitory phosphorylation hepatocyte nuclear...
In recent years, surface electromyogram signals have been increasingly used to operate wearable devices. These devices can aid help workers or soldiers lower the load in task boost efficiency. However, achieving effective signal prediction has always a challenge. It is critical use an appropriate preprocessing method and algorithm when developing controller that accurately predict control human movements real time. For this purpose, article investigates effect of various methods algorithms...
Background Knee osteoarthritis (KOA) presents a significant public health challenge due to its hazards and increasingly severe trends. Addressing this requires targeted investigation into the prevalence identification of risk factors for KOA across different regions, especially in populous vast China. Therefore, cross-sectional survey was conducted Nanjing, China, with aim investigating among individuals aged 50 above. Method A total 1,045 subjects were selected using stratified random...
Introduction To examine the effects of tap dance (TD) on dynamic plantar pressure, static postural stability, ankle range motion (ROM), and lower extremity functional strength in patients at risk diabetic foot (DF). Research design methods A randomised, single-blinded, two-arm prospective study 40 DF was conducted. The intervention group (n=20) received 16 weeks TD training (60 min/session×3 sessions/week). control attended four educational workshops (1 hour/session×1 session/month). Plantar...
The Community Health Activities Model Program for Seniors questionnaires (CHAMPS-Q) is one of the most extensively used instruments in assessing physical activity among older adults. However, no study had translated CHAMPS-Q into Chinese, and evaluations were made on psychometric properties Chinese population. Considering cultural differences perceptions language, context living habits, this was necessary to 1) translate cross-culturally adapt original CHAMPS-Q, 2) examine test-retest...
Objective To compare the accuracy of weight-bearing training using biofeedback with conventional for partial patients, and factors influencing accuracy. Methods Seven healthy volunteers were recruited to practice on a treadmill their body weight partially supported paired elbow crutches. The reduction was controlled by subjects means verbal prompting from an experienced therapist, or bathroom scale sound-vibrating PierenStep gait quantization system. system also used collect data. All...
Objective To investigate the effects of mirror therapy supplemented with motor imaging training on upper extremity functions hemiplegic stroke patients and their ability in activities daily living (ADL).Methods Forty-four were divided into a control group an experimental 22 each.All given routine rehabilitation treatment.In addition,the was 30 minutes 15 training.The occupational therapy.All assessed Brunnstrom staging,the functional test for extremity-Hong Kong (FTHUE-HK) Barthel index (BI)...
Objective To study the effects of dynamic,support-inducing exercise on support,balance and gait ability patients with moderate-to-severe hemiplegia after stroke.Methods Fourteen stroke were randomly assigned to an experimental or a control group (7 cases each).The in received both routine exercises,while exercises only.Before training 40 60 days training,their functional capacity was evaluated Chinese scale (CSS) for neurological deficits,Berg's balance (BBS) using ambulation categories...
BMW and Chevrolet have been two of the biggest car manufacturers for more than 100 years. They both played an important role in human history development automotive industry. In this century, there are so many legendary types cars that they made, most famous M3 Cavaliers. To learn performance vehicles, we use a few different methodologies to help us gain insightful view them. For instance, series basic dynamic equations, mathematical modeling, along computational modeling demonstrate...