A5042686770- Pancreatic function and diabetes
- Image Enhancement Techniques
- Pancreatic and Hepatic Oncology Research
- Advanced Vision and Imaging
- Pancreatitis Pathology and Treatment
- Remote-Sensing Image Classification
- Face recognition and analysis
- Color Science and Applications
- Diabetes Management and Research
- Domain Adaptation and Few-Shot Learning
- Advanced Data Compression Techniques
- Video Coding and Compression Technologies
- Diabetes and associated disorders
- Facial Rejuvenation and Surgery Techniques
- Advanced Neural Network Applications
- Facial Nerve Paralysis Treatment and Research
- Image Processing Techniques and Applications
- Image and Video Quality Assessment
- CCD and CMOS Imaging Sensors
- Posttraumatic Stress Disorder Research
- 3D IC and TSV technologies
- Diabetes Treatment and Management
- Neuroscience and Neural Engineering
- Treatment of Major Depression
- Interprofessional Education and Collaboration
Beckman Research Institute
2016-2024
City of Hope
2016-2024
MediaTek (Taiwan)
2015-2024
City Of Hope National Medical Center
2024
MediaTek (China)
2015-2021
VA Sepulveda Ambulatory Care Center
2016
VA Greater Los Angeles Healthcare System
2014-2016
Neurobehavioral Systems
2016
In this paper, we present CLCC, a novel contrastive learning framework for color constancy. Contrastive has been applied high-quality visual representations image classification. One key aspect to yield useful classification is design illuminant invariant augmentations. However, the assumption conflicts with nature of constancy task, which aims estimate given raw image. Therefore, construct effective pairs better illuminant-dependent features via raw-domain augmentation. On NUS-8 dataset,...
Enhancing video quality is critical for achieving a boosted user experience on smart devices including mobiles, televisions, and monitors. Practical hardware designs should deliver high performance with minimal resources under the stringent limitations related to bandwidth, area energy budget. The widespread usage of deep-learning algorithms in image processing tasks, super-resolution (SR) noise-reduction (NR), has further emphasized necessity energy-efficient solutions. Therefore, an...
Technologies for coding non-camera-captured video contents have received great interests lately due to the rapid growth of application areas such as wireless display and screen sharing, etc. In response market demands, ITU-T Video Coding Expert Group ISO/IEC Motion Picture jointly launched a new standardization project, i.e. High-Efficiency (HEVC) extensions on content (HEVC SCC). Several tools, including intra block copy, palette coding, adaptive color transform, motion resolution, been...
Depth estimation is a long-lasting yet important task in computer vision. Most of the previous works try to estimate depth from input images and assume are all-in-focus (AiF), which less common real-world applications. On other hand, few take defocus blur into account consider it as another cue for estimation. In this paper, we propose method not only map but an AiF image set with different focus positions (known focal stack). We design shared architecture exploit relationship between As...
Progenitor cells capable of self-renewal and differentiation in the adult human pancreas are an under-explored resource for regenerative medicine. Using micro-manipulation three-dimensional colony assays we identify within exocrine that resemble progenitor cells. Exocrine tissues were dissociated into single plated a assay containing methylcellulose 5% Matrigel. A subpopulation ductal formed colonies differentiated ductal, acinar, endocrine lineage cells, expanded up to 300-fold with ROCK...
A 4K×2K H.265/HEVC video codec chip is fabricated in a 28nm CMOS process with core area of 2.16mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . This LSI integrates dual-standard (H.265 and H.264) series prevalent (VC-1, WMV-7/8/9, VP-6/8, AVS, RM-8/9/10, MPEG-2/4) decoders into single chip. It contains 3,558K logic gates 308KB internal SRAM. Moreover, it simplifies intra/inter-rate-distortion optimization (RDO) processes reduces...
Abstract Pancreatic ductal progenitor cells have been proposed to contribute adult tissue maintenance and regeneration after injury, but the identity of such remains elusive. Here, from mice, we identify a near homogenous population progenitor-like clusters, with an average 8 per cluster. They are rare subpopulation, about 0.1% total pancreatic cells, can be sorted using fluorescence-activated cell sorter CD133highCD71lowFSCmid-high phenotype. exhibit properties in self-renewal tri-lineage...
Ductal progenitor-like cells are a sub-population of ductal in the adult human pancreas that have potential to contribute regenerative medicine. However, microenvironmental cues regulate their activation poorly understood. Here, we establish 3-dimensional suspension culture system containing six defined soluble factors which primary and non-progenitor survive but do not proliferate. Expansion polarization occur when provided with low concentration (5% v/v) Matrigel, sarcoma cell product...
Stem and progenitor cells from the adult pancreas could be a potential source of therapeutic beta-like for treating patients with type 1 diabetes. However, it is still unknown whether stem exist in pancreas. Research strategies using cre-lox lineage-tracing mice have yielded results that either support or refute idea beta can generated ducts, presumed location where pancreatic progenitors may reside. These vivo methods, however, cannot answer questions self-renewal multi-lineage...
<p dir="ltr"><b>ABSTRACT</b></p><p dir="ltr">Exocrine-to-endocrine crosstalk in the pancreas is crucial to maintain beta cell function. However, molecular mechanisms underlying this are largely undefined. Trefoil factor 2 (Tff2) a secreted known promote proliferation of cells <i>in vitro</i>, but its physiological role vivo</i> unknown. Also, it remains unclear which pancreatic type expresses Tff2 protein. We therefore created mouse model with...
<p dir="ltr"><b>ABSTRACT</b></p><p dir="ltr">Exocrine-to-endocrine crosstalk in the pancreas is crucial to maintain beta cell function. However, molecular mechanisms underlying this are largely undefined. Trefoil factor 2 (Tff2) a secreted known promote proliferation of cells <i>in vitro</i>, but its physiological role vivo</i> unknown. Also, it remains unclear which pancreatic type expresses Tff2 protein. We therefore created mouse model with...
Network spaces have been known as a critical factor in both handcrafted network designs or defining search for Neural Architecture Search (NAS). However, an effective space involves tremendous prior knowledge and/or manual effort, and additional constraints are required to discover efficiency-aware architectures. In this paper, we define new problem, Space (NSS), searching favorable instead of single architecture. We propose NSS method directly efficient-aware automatically, reducing the...
Exocrine-to-endocrine cross talk in the pancreas is crucial to maintain β-cell function. However, molecular mechanisms underlying this are largely undefined. Trefoil factor 2 (Tff2) a secreted known promote proliferation of β-cells vitro, but its physiological role vivo unknown. Also, it remains unclear which pancreatic cell type expresses Tff2 protein. We therefore created mouse model with conditional knockout murine pancreas. find that protein preferentially expressed acinar not ductal or...
While recent works on blind face image restoration have successfully produced impressive high-quality (HQ) images with abundant details from low-quality (LQ) input images, the generated content may not accurately reflect real appearance of a person. To address this problem, incorporating well-shot personal as additional reference inputs could be promising strategy. Inspired by success Latent Diffusion Model (LDM), we propose ReF-LDM, an adaptation LDM designed to generate HQ conditioned one...
Despite the recent developments in 3D Face Reconstruction from occluded and noisy face images, performance is still unsatisfactory. Moreover, most existing methods rely on additional dependencies, posing numerous constraints over training procedure. Therefore, we propose a Self-Supervised RObustifying GUidancE (ROGUE) framework to obtain robustness against occlusions noise images. The proposed network contains 1) Guidance Pipeline coefficients for clean faces 2) Robustification acquire...
Majority of tasks are medium and light loads
In this paper, we present CLCC, a novel contrastive learning framework for color constancy. Contrastive has been applied high-quality visual representations image classification. One key aspect to yield useful classification is design illuminant invariant augmentations. However, the assumption conflicts with nature of constancy task, which aims estimate given raw image. Therefore, construct effective pairs better illuminant-dependent features via raw-domain augmentation. On NUS-8 dataset,...
A 2MPixels@30fps 24b high-dynamic-range image processing chip is fabricated in a 16nm CMOS process with core area of 5.69mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . This LSI integrates multiple color-filter-array (RGGB, RGB-Ir, RCCC, RCCB, and Mono) into single chip. It contains 2,067k logic gates 628.3kB internal SRAM. Moreover, it supports multiple-exposure sensor up to 24b/color components fusion results achieve 2.1 x dynamic...
Depth estimation is a long-lasting yet important task in computer vision. Most of the previous works try to estimate depth from input images and assume are all-in-focus (AiF), which less common real-world applications. On other hand, few take defocus blur into account consider it as another cue for estimation. In this paper, we propose method not only map but an AiF image set with different focus positions (known focal stack). We design shared architecture exploit relationship between As...
Stem and progenitor cells from the adult pancreas could be a potential source of therapeutic beta-like for treating patients with type 1 diabetes. However, it is still unknown whether stem exist in pancreas. Research strategies using cre-lox lineage-tracing mice have yielded results that either support or refute idea beta can generated ducts, presumed location where pancreatic progenitors may reside. These vivo methods, however, cannot answer questions self-renewal multi-lineage...
Introduction. Islet transplantation (IT) restores insulin production in individuals with severe type 1 diabetes (T1D). However, after isolation, human islets rapidly loose function isolation and must be transplanted within about two to three days for best outcomes. This limits access standard IT combined kidney transplantation. Current methods of cultivating isolated fail appreciate the role extracellular matrix islet health do not permit long-term culture. In this study, were cultured a 3D...
Abstract Pancreatic ducts function to deliver digestive enzymes into the intestines. Upon injury, can become proliferative and contribute tissue regeneration; however, identity of ductal cells that these processes is unknown. We combined fluorescence-activated cell sorting, a methylcellulose-containing 3-dimensional culture, droplet RNA-sequencing, clonal lineage tracing tool identify isolate distinct subpopulation pancreatic exhibit progenitor properties. These are unique in they form...