Nicole L. Gentile

ORCID: 0000-0002-9548-7012
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About
Contact & Profiles
Research Areas
  • Long-Term Effects of COVID-19
  • COVID-19 and Mental Health
  • Intensive Care Unit Cognitive Disorders
  • Thermal Regulation in Medicine
  • COVID-19 Clinical Research Studies
  • Molecular Biology Techniques and Applications
  • Sepsis Diagnosis and Treatment
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Bacterial Identification and Susceptibility Testing
  • SARS-CoV-2 detection and testing
  • Physical Activity and Health
  • Pain Mechanisms and Treatments
  • Viral gastroenteritis research and epidemiology
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Cardiovascular and exercise physiology
  • Cardiac Health and Mental Health
  • Virus-based gene therapy research
  • Artificial Intelligence in Healthcare and Education
  • Diabetes Management and Research
  • Ethics in Clinical Research
  • Central Venous Catheters and Hemodialysis
  • Telemedicine and Telehealth Implementation
  • Multiple Sclerosis Research Studies
  • Biosensors and Analytical Detection

University of Washington
2017-2025

Theodore Roosevelt High School
2024

Seattle University
2024

University of Washington Medical Center
2022

University of California, Davis
2008-2012

National Institute of Biomedical Imaging and Bioengineering
2008-2012

Center Point
2008-2012

Lawrence Livermore National Laboratory
2008

Research Network (United States)
2008

National Institutes of Health
2008

Importance Long-term sequelae after symptomatic SARS-CoV-2 infection may impact well-being, yet existing data primarily focus on discrete symptoms and/or health care use. Objective To compare patient-reported outcomes of physical, mental, and social well-being among adults with illness who received a positive vs negative test result for infection. Design, Setting, Participants This cohort study was planned interim analysis an ongoing multicenter prospective longitudinal registry (the...

10.1001/jamanetworkopen.2022.44486 article EN cc-by-nc-nd JAMA Network Open 2022-12-01
Michael Gottlieb Erica S. Spatz Huihui Yu Lauren E. Wisk Joann G. Elmore and 95 more Nicole L. Gentile Mandy J. Hill Ryan Huebinger Ahamed H. Idris Efrat R Kean Katherine Koo Shuxia Li Samuel McDonald Juan Carlos C. Montoy Graham Nichol Kelli N. O’Laughlin Ian D. Plumb Kristin L. Rising Michelle Santangelo Sharon Saydah Ralph C. Wang Arjun K. Venkatesh Kari A. Stephens Robert A. Weinstein Robert A. Weinstein Michael Gottlieb Michelle Santangelo Katherine Koo Antonia Derden Michael Gottlieb Kristyn Gatling Diego Cordero Geoffrey Yang Marshall Kaadan Minna Hassaballa Ryan Jerger Zohaib Ahmed Michael Choi Arjun K. Venkatesh Erica S. Spatz Zhenqiu Lin Shuxia Li Huihui Yu Mengni Liu Arjun K. Venkatesh Erica S. Spatz Andrew Ulrich Jeremiah Kinsman Jocelyn Dorney Senyte Pierce Xavier Puente Graham Nichol Kari A. Stephens Jill Anderson Dana Morse Karen Adams Zenoura Maat Tracy Stober Kelli N. O’Laughlin Nikki Gentile Rachel E Geyer Michael Willis Luis Ruiz Kerry Malone Jasmine Park Kristin L. Rising Elizabeth Krebs Morgan Kelly Kevin Schaeffer Paavali Hannikainen Lindsey Shughart Hailey Shughart Nicole Renzi Grace Amadio Dylan Grau Phillip B. Watts David Cheng Jessica Miao Carly Shutty Alex Charlton Mandy J. Hill Summer Chavez Arun Kane Peter Nikonowicz Ahamed H. Idris Samuel McDonald David Gallegos Riley Martin Joann G. Elmore Lauren E. Wisk Michelle L’Hommedieu Chris Chandler Megan Eguchi Kate Diaz Roldan Nicole Villegas Raul Moreno Robertz Rodrigue Ralph C. Wang Juan Carlos C. Montoy Robin Kemball

The prevalence, incidence, and interrelationships of persistent symptoms after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection vary. There are limited data on specific phenotypes symptoms. Using latent class analysis (LCA) modeling, we sought to identify whether COVID-19 were present 3 months 6 post-infection.

10.1093/ofid/ofad277 article EN cc-by-nc-nd Open Forum Infectious Diseases 2023-05-31

Introduction Data on ethnic and racial differences in symptoms health-related impacts following SARS-CoV-2 infection are limited. We aimed to estimate the 3 6 months after first infection. Methods Participants included adults with enrolled a prospective multicenter US study between 12/11/2020 7/4/2022 as primary cohort of interest, well SARS-CoV-2-negative account for non-SARS-CoV-2-infection impacts, who completed enrollment 3-month surveys ( N = 3,161; 2,402 SARS-CoV-2-positive, 759...

10.3389/fpubh.2023.1324636 article EN cc-by Frontiers in Public Health 2024-01-30
Elizabeth R. Unger Jin-Mann S. Lin Lauren E. Wisk Huihui Yu Michelle L’Hommedieu and 95 more Helen Lavretsky Juan Carlos C. Montoy Michael Gottlieb Kristin L. Rising Nicole L. Gentile Michelle Santangelo Arjun K. Venkatesh Robert M. Rodriguez Mandy J. Hill Rachel E. Geyer Efrat R. Kean Sharon Saydah Samuel McDonald Ryan Huebinger Ahamed H. Idris Jocelyn Dorney Bala Hota Erica S. Spatz Kari A. Stephens Robert A. Weinstein Joann G. Elmore Katherine Koo Antonia Derden Kristyn Gatling Diego Cordero Geoffrey Yang Amro Kaadan Minna Hassaballa Ryan Jerger Zohaib Ahmed Michael Choi Ariana Pavlopoulos Avinash Kesari Caitlin A Gaylord Chloe Gomez Elizabeth Lomas Phouthavang Boliboun Krisna Patel Caitlin Malicki Zhenqiu Lin Shuxia Li Imtiaz Ebna Mannan Zimo Yang Mengni Liu Andrew Ulrich Jeremiah Kinsman Senyte Pierce Xavier Puente W. Salah Graham Nichol Jill Anderson Mary Schiffgens Dana Morse Karen Adams Tracy Stober Zenoura Maat Kelli N. O’Laughlin Michael Willis Zihan Zhang Gary Chang Victoria Lyon Robin E. Klabbers Luis Ruiz Kerry Malone Jasmine Park Nicole Renzi Phillip B. Watts Morgan Kelly Kevin Schaeffer Dylan Grau David Cheng Carly Shutty Alex Charlton Lindsey Shughart Hailey Shughart Grace Amadio Jessica Miao Paavali Hannikainen Chris Chandler Kate Diaz Roldan Megan Eguchi Raul Moreno Ralph C. Wang Robin Kemball Virginia Chan Cecilia Lara Chavez Angela Wong Mireya Arreguin Arun Kane Peter Nikonowicz Sarah G. H. Sapp David Gallegos Katherine R. Martin Ian D. Plumb Aron J. Hall

Importance Chronic symptoms reported following an infection with SARS-CoV-2, such as cognitive problems, overlap included in the definition of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Objective To evaluate prevalence ME/CFS-like illness subsequent to acute SARS-CoV-2 infection, changes ME/CFS through 12 months follow-up, and association test results at infection–like index illness. Design, Setting, Participants This prospective, multisite, longitudinal cohort study...

10.1001/jamanetworkopen.2024.23555 article EN cc-by-nc-nd JAMA Network Open 2024-07-24

Abstract Background Recovery from SARS CoV-2 infection is expected within 3 months. Long COVID occurs after SARS-CoV-2 when symptoms are present for more than months that continuous, relapsing and remitting, or progressive. Better understanding of illness trajectories could strengthen patient care support. Methods We characterized functional impairments, quality life (QoL), cognition among patients who recovered (without COVID), (Recovered remained symptomatic (Long COVID). Among 7305...

10.1186/s12879-024-10158-w article EN cc-by BMC Infectious Diseases 2024-11-05

Background: We assessed the performance of a point-of-care (POC) glucose meter system (GMS) with multitasking test strip by using locally-smoothed (LS) median absolute difference (MAD) curve method in conjunction modified Bland-Altman plot and superimposed International Organization for Standardization (ISO) 15197 tolerance bands. analyzed tight glycemic control (TGC). Methods: A oxidase enzyme multilayer-gold, multielectrode, four-well (StatStrip™, NOVA Biomedical, Waltham, MA) was used....

10.1089/dia.2008.0049 article EN Diabetes Technology & Therapeutics 2008-12-01

Physical activity is important to prevent and manage multiple chronic medical conditions. The objective of this study was describe the implementation a physical vital sign (PAVS) in primary care setting examine association between with demographic characteristics disease burden.

10.5888/pcd19.210457 article EN public-domain Preventing Chronic Disease 2022-06-22

Background : Physical inactivity is a risk factor for many chronic conditions. This retrospective cohort study examined associations between physical activity (PA) with health care utilization (HU). Methods A PA vital sign was recorded in clinics from January 2018 to December 2020. Patients were categorized as inactive, insufficiently active, or sufficiently active by US aerobic guidelines. Associations and visits (inpatient admissions, emergency department, urgent care, primary care)...

10.1123/jpah.2022-0266 article EN Journal of Physical Activity and Health 2022-12-09

The goal of this study was to construct a single-tube multiplex molecular diagnostic assay using linear-after-the-exponential (LATE)-PCR for the detection 17 microbial pathogens commonly associated with septicaemia.The described here detects sepsis via amplification and analysis gene-specific sequences. their targeted genes were: Klebsiella spp. (phoE); Acinetobacter baumannii (gyrB); Staphylococcus aureus (spa); Enterobacter (thdF); Pseudomonas aeruginosa (toxA); coagulase-negative...

10.1111/jam.12061 article EN Journal of Applied Microbiology 2012-11-08

Abstract Background Home testing for influenza has the potential to aid triage and management decisions patients with influenza-like illness. As yet, little is known about effect of home on clinical decision-making via telehealth. The goal this study was determine clinicians’ decision thresholds whether availability a test affects decisions. Methods We identified primary care physicians at 4 different sites in US, largely in-person continuing education meetings. Clinicians were asked each...

10.1186/s12875-022-01675-1 article EN cc-by BMC Primary Care 2022-04-13

Point-of-care testing is useful when caring for patients in hospital settings and emergency disaster situations. However, point-of-care professional practice lacks components, such as standardization, harmonization, consistency, which would substantially improve patient care if implemented. Therefore, we propose adoption of whole-blood standards, harmonization among methods, tighter quality control constraints. Granting these 3 wishes will at the point ultimately diagnoses, treatment...

10.1097/poc.0b013e318182fa85 article EN Point of Care The Journal of Near-Patient Testing & Technology 2008-09-01

Objective The 2004 earthquake/tsunami devastated Southeast Asia. We studied point-of-care testing (POCT) and O2 saturation monitoring in Phang Nga, hardest hit southern coastal province, to develop preparedness strategies for low-resource small-world networks (SWNs). Design, Setting, Participants Early 2005, we surveyed 4 provinces then, 2007–2011, focused on Nga with new field/phone/mail/e-mail/fax surveys of 7 primary care units, all community hospitals, both regional hospitals. used...

10.1097/poc.0b013e318265f3d4 article EN Point of Care The Journal of Near-Patient Testing & Technology 2013-02-13

Telehealth-embedded knowledge packets in conjuction with point-of-care testing strategically placed small-world networks for regional health care delivery can provide multilingual education and intellectual connectivity at levels of sophistication appropriate the practice modern evidence-based medicine worldwide. In addition, demographic topographic integration efficient critical, emergency, disaster thereby improve public preparedness, especially underserved low-resource settings most need help.

10.1097/poc.0b013e318172a8a1 article EN Point of Care The Journal of Near-Patient Testing & Technology 2008-06-01

<h3>Context:</h3> Persistent pain is experienced among nearly half of the patients with long COVID (LC). However, associated LC has not been well understood and there are no current standardized treatments. <h3>Objective:</h3> To document lived experience pain, including how they access receive healthcare, to improve services for evaluation treatment. <h3>Study Design:</h3> We conducted seven semi-structured focus groups 25 adult who had a positive test, reported as one their primary...

10.1370/afm.22.s1.6446 article EN The Annals of Family Medicine 2024-11-20

Abstract Aims Alcohol consumption along with negative sequelae from excess alcohol intake increased during the COVID-19 pandemic. We evaluated association between binge use and long-term functional outcomes among COVID-19-positive individuals. Methods Using a prospective, longitudinal, multisite cohort study design, we mental physical using Patient-Reported Outcomes Measurement Information System (PROMIS)-29 scores three six months postinfection. Eligible patients were those who presented...

10.1093/alcalc/agae086 article EN cc-by Alcohol and Alcoholism 2024-11-18

To verify monoplex and multiplex gene-specific linear-after-the-exponential polymerase chain reaction (LATE-PCR) assays for identifying 17 microbial pathogens (i.e., Klebsiella sp., Acinetobacter baumannii, Staphylococcus aureus, Enterobacter Pseudomonas aeruginosa, coagulase negative staphylococci, Enterococcus Candida sp.) commonly associated with septicaemia using clinical isolates.Clinical isolates of each target pathogen were collected from the University California, Davis Medical...

10.1111/jam.12062 article EN Journal of Applied Microbiology 2012-11-08

# Beware of Right Renal Vein Valves in Transplanted Kidneys: Valvuloplasty a Donor Kidney {#article-title-2} Here we present an unusual case renal vein thrombectomy after allograft reperfusion secondary to venous outflow obstruction (VOO). While VOO is unfortunate

10.1043/1524-5012-17.1.2 article EN PubMed 2017-01-01

The 2004 tsunami in Southeast Asia and Hurricane Katrina showed that point-of-care testing (POCT) was both needed feasible acute disaster response follow-up recovery. However, POCT devices made for routine clinical use the consumer market are not adequate conditions. We explain rationale developing field-robust durable single unit-use tests context of 3 "wishes." Then, we challenge inventors, innovators, industry to produce reagents will meet needs rural emergencies care improve preparedness...

10.1097/poc.0b013e318182f9c4 article EN Point of Care The Journal of Near-Patient Testing & Technology 2008-09-01
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