Desheng Li

ORCID: 0000-0002-9587-8451
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About
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Research Areas
  • Moyamoya disease diagnosis and treatment
  • Intracranial Aneurysms: Treatment and Complications
  • Neurological Complications and Syndromes
  • Cerebrovascular and genetic disorders
  • Muscle activation and electromyography studies
  • Cerebrovascular and Carotid Artery Diseases
  • Mathematical Biology Tumor Growth
  • Knee injuries and reconstruction techniques
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Renal Transplantation Outcomes and Treatments
  • Stroke Rehabilitation and Recovery
  • Organ and Tissue Transplantation Research
  • Musculoskeletal pain and rehabilitation
  • Total Knee Arthroplasty Outcomes
  • Balance, Gait, and Falls Prevention
  • Stability and Controllability of Differential Equations
  • Lung Cancer Diagnosis and Treatment
  • Spinal Fractures and Fixation Techniques
  • Animal Nutrition and Physiology
  • Esophageal Cancer Research and Treatment
  • Cardiac electrophysiology and arrhythmias
  • Bone Metabolism and Diseases
  • Cardiac Fibrosis and Remodeling
  • Blood Pressure and Hypertension Studies
  • Liver Disease and Transplantation

ShenZhen People’s Hospital
2021-2025

Hubei University of Medicine
2017-2025

Qinghai University
2024-2025

Jinzhou Medical University
2021-2023

Tianjin University
2023

First Affiliated Hospital of Xinjiang Medical University
2023

Xinjiang Medical University
2023

Creative Commons
2023

Yahoo (United Kingdom)
2023

Chinese People's Liberation Army
2022

<b><i>Background:</i></b> There was few detailed demographic and clinical data about Chinese patients with moyamoya disease. Here we describe the features, surgical treatment, long-term outcome of pediatric disease at a single institution in China. <b><i>Methods:</i></b> Our cohort included 288 The characteristics were obtained by retrospective chart review evaluated using stroke status. Univariate multivariate logistic regression analyses...

10.1159/000369524 article EN Cerebrovascular Diseases 2015-01-01

<h3>Objective</h3> Precise genetic analyses were conducted with ring finger protein 213 (<i>RNF213</i>) in relation to a particular clinical phenotype Chinese patients moyamoya disease (MMD) determine whether heterozygosity is responsible for the early-onset and severe form of this disease. <h3>Methods</h3> A case–control study <i>RNF213</i> p.R4810K involving 1,385 MMD 2,903 normal control participants was performed. Correlation between genotype or different features also statistically...

10.1212/wnl.0000000000008901 article EN cc-by-nc-nd Neurology 2020-01-17

Ischemic stroke (IS), a leading cause of global disability and mortality, is characterized by white matter damage demyelination. Despite advances, the molecular mechanisms driving post-IS myelin pathology remain poorly understood, limiting therapeutic development. This study investigates key myelin-related genes (MRGs) their regulatory networks to identify novel targets. A transient middle cerebral artery occlusion (MCAO) model was established in C57BL/6 mice, with brain tissues collected at...

10.1007/s10142-025-01573-6 article EN cc-by-nc-nd Functional & Integrative Genomics 2025-03-14

Objective: Accurate risk stratification at an early stage may reduce the incidence of infection and improve survival rate recipients by adopting targeted interventions. This study aimed to develop a nomogram predict multidrug-resistant organism (MDRO) infections in liver transplant (LT) recipients. Methods: We retrospectively collected clinical data from 301 LT randomly divided them into training set (210 cases) validation (91 using 7:3 split ratio. Factors related MDRO after were determined...

10.3390/bioengineering12040417 article EN cc-by Bioengineering 2025-04-14

The objective of this study was to investigate long-term outcomes after encephaloduroarteriosynangiosis (EDAS) for the treatment hemorrhagic moyamoya disease (MMD) and identify risk factors recurrent hemorrhages.

10.3171/2017.12.jns172246 article EN Journal of neurosurgery 2018-06-01

OBJECTIVE Debate exists regarding the merits and shortcomings of an indirect bypass procedure for treating adult patients with moyamoya disease (MMD). Considerable variation in neovascularization occurs among different organs diabetes mellitus. Here, effect encephaloduroarteriosynangiosis on MMD associated Type 2 mellitus (T2DM) is evaluated. METHODS A retrospective 1:2 matched case-control study was conducted or without T2DM (n = 180). Postoperative collateral formations were graded...

10.3171/2015.7.jns15218 article EN Journal of neurosurgery 2016-01-08

Hemorrhage is a major category of the clinical symptoms moyamoya disease (MMD). Intracerebral and intraventricular hemorrhages are most common in MMD, subarachnoid (SAHs) notably rare. There have only been few previous case reports this imaging manifestation. In present study, we investigated neuroimaging features MMD patients who presented with SAH sought to identify possible causes hemorrhage.The right left cerebral hemispheres each patient were identified as hemorrhagic or...

10.3109/02688697.2015.1071327 article EN British Journal of Neurosurgery 2015-08-24

Background The clinical characteristics and associated risk factors for recipients who experience multidrug-resistant organism (MDRO) bloodstream infections after liver transplantation are poorly understood. This study aimed to analyse the epidemiology of pathogenic bacteria identify in patients underwent MDRO transplantation.

10.1080/20523211.2024.2390072 article EN cc-by Journal of Pharmaceutical Policy and Practice 2024-08-20

To explore the long-term progression of neoangiogenesis after indirect revascularization for moyamoya disease (MMD).We enrolled patients who were diagnosed with MMD and treated by encephaloduroarteriosynangiosis (EDAS) surgery at our center from December 2002 through September 2009. A comparative study between short-term (6-12 months) (duration ≥ 8 years) follow-up angiographies was performed. The development collateral circulation EDAS graded according to system described Matsushima grade...

10.3389/fneur.2022.861187 article EN cc-by Frontiers in Neurology 2022-05-06

[Purpose] The aim of this study was to explore the effects different frequencies rhythmic auditory cueing (RAC) on stride length, cadence, and gait speed in healthy young females. findings might be used as clinical guidance physical therapy for choosing suitable frequency RAC. [Subjects] Thirteen females were recruited study. [Methods] Ten meters walking tests measured all subjects under 4 conditions with each repeated 3 times a 3-min seated rest period between repetitions. Subjects first...

10.1589/jpts.27.485 article EN Journal of Physical Therapy Science 2015-01-01

[Purpose] The aim of this study was to investigate the change in electromechanical (EMG) reaction time (RT) human rectus femoris after neuromuscular joint facilitation (NJF) treatment. [Subjects] subjects were 17 healthy males who divided into two groups: a NJF group and control group. consisted 10 subjects, 7 subjects. [Methods] Participants received We measured EMG-RT, premotor (PMT) motor (MT) during knee extension movement before, immediately after, 10, 20 30 minutes intervention....

10.1589/jpts.24.55 article EN Journal of Physical Therapy Science 2012-01-01

Abstract Introduction: Deficiency of testosterone was associated with the susceptibility atrial fibrillation (AF). Angiotensin‐II (AngII) receptor antagonists were shown to reduce AF by improving electrical remodeling. This study investigated effects and mechanism valsartan, an AngII antagonist, on deficiency. Methods Results: Five‐week‐old male ICR mice castrated valsartan administered orally (50 mg/kg/d). High‐frequency stimulation method used induce arrhythmia. Patch‐clamp technique for...

10.1111/jce.13697 article EN Journal of Cardiovascular Electrophysiology 2018-07-17

OBJECTIVE This prospective study was designed to confirm the role of atorvastatin in collateral circulation formation induced by encephaloduroarteriosynangiosis (EDAS) patients with moyamoya disease (MMD). METHODS Patients who were diagnosed MMD at Department Neurosurgery Fifth Medical Center Chinese PLA General Hospital, Beijing, China, between June 2017 and May 2018 included. Blood samples obtained from an antecubital vein analyzed using flow cytometry. Endothelial progenitor cells (EPCs)...

10.3171/2021.6.focus21112 article EN Neurosurgical FOCUS 2021-09-01

Abstract A total of 60 sows (Landrace × Yorkshire, average parity was 1.39) were used to evaluate the effects soy isoflavones (ISO) supplementation on reproductive performance, serum antioxidant enzyme parameters, and milk compositions sows, growth performance offspring. Sows randomly assigned 4 groups based parity. There 15 replicates per treatment. Dietary treatments a corn‐soybean meal‐based basal diet supplemented with 0, 10, 20, or 40 mg/kg ISO. With increase ISO dosage, daily feed...

10.1111/jpn.13667 article EN Journal of Animal Physiology and Animal Nutrition 2021-12-03
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