A5048835327- Hip disorders and treatments
- Bone and Joint Diseases
- Orthopaedic implants and arthroplasty
- Mesenchymal stem cell research
- Cancer-related molecular mechanisms research
- Sleep and Wakefulness Research
- MicroRNA in disease regulation
- Advanced Glycation End Products research
- Diabetic Foot Ulcer Assessment and Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Tissue Engineering and Regenerative Medicine
- Dementia and Cognitive Impairment Research
- Gestational Diabetes Research and Management
- Medicinal Plants and Neuroprotection
- Neurological Disease Mechanisms and Treatments
- Maternal and fetal healthcare
- Antioxidants, Aging, Portulaca oleracea
- Hip and Femur Fractures
- Piperaceae Chemical and Biological Studies
- Knee injuries and reconstruction techniques
- Pelvic and Acetabular Injuries
- Bone fractures and treatments
- Cardiac Fibrosis and Remodeling
- RNA modifications and cancer
- Memory and Neural Mechanisms
Affiliated Zhongshan Hospital of Dalian University
2014-2023
Dalian University
2023
Chinese PLA General Hospital
2022
State Administration of Traditional Chinese Medicine of the People's Republic of China
2020
Specim (Finland)
2020
Weatherford College
2020
Dalian University of Technology
2011-2015
The body is unable to repair and regenerate large area bone defects. Moreover, the capacity of articular cartilage very limited. There has long been a lack effective treatments for osteochondral lesions. engineered tissue with biphase synthetic become one hot research fields over past few years. In this study, an integrated biomanufacturing platform was constructed marrow mesenchymal stem cells (BMSCs)/porous tantalum (pTa) associated chondrocytes/collagen membranes (CM) defects in...
Avascular necrosis of femoral head and nonunion is a major complication after the treatment displaced neck fracture in young adults. The purpose this study was to introduce new technique using biodegradable magnesium screws vascularised iliac grafting for Totally 19 patients with treated were retrospectively reviewed. steps included harvesting vascularized graft, fixing combined implantation. All followed an average 16 months (range: 8–24 months). Clinical radiological outcomes evaluated. In...
The prevalence of developmental dysplasia the hip (DDH) is unknown in China. We aimed to determine DDH Chinese adults.In this study, we performed a cross-sectional survey nationally representative sample adults. All participants underwent questionnaire investigation, physical examination, and X-ray examination. Factors associated with were analyzed logistic regression.We invited 29,180 individuals aged 18 years over participate, randomly selected from primary sampling units (street districts...
The use of the bone flap transfer has been reported to be successful in treatment patients with early medium stage (Ficat and Arlet I‐III) osteonecrosis femoral head (ONFH). We examined vascular anatomy blood supply greater trochanter area evaluated feasibility revascularization by using pedicled transverse gluteus medius branches lateral circumflex artery. Based on study, from January 2002 May 2004, 32 ONFH were treated trochanteric double vessels. Fifteen heads Ficat II 17 III. mean...
Steroid-associated osteonecrosis of the femoral head remains a challenging problem in orthopedics worldwide. One pathomechanism is ischemia head, as result thrombus formation and vasoconstriction. The present study investigates effects combination prevention with enoxaparin EGb 761 on steroid-associated ONFH rabbits. Rabbits were randomly divided into 5 groups (control group, model ginkgo group). With exception control rabbits modeled lipopolysaccharide methylprednisolone acetate. Starting...
Abstract In this report, we present the long‐term results of using combined vascularized iliac and greater trochanter graftings for reconstruction osteonecrosis femoral head (ONFH) with collapse in three patients. Necrosis over two‐thirds were observed these patients, Harris hip scores (HHS) 46, 38, 49 points, respectively. When patients underwent procedures, ages ranged from 20 to 28 years old. The followed‐up 20–24 years. X‐ray examinations showed no progress necrosis or deformity after...
Stroke survivors are accompanied by dysfunctions, greatly declining their activities of daily living and bringing burden to families societies. Although modern rehabilitation therapy has a systematic program in post-stroke motor rehabilitation, numbers patients still recover slowly. Eye-acupuncture (EA), as an important type acupuncture, been widely applied effectively stroke for about 50 years. So we combine EA with which achieved successful results. Therefore, need adopt objective accurate...
Objective To explore the clinical outcome of vascularized iliac bone flap combined with tantalum rod implantation for treatment osteonecrosis femoral head (ONFH).Methods Totally 28 cases (36 hips) non traumatic avascular necrosis patients from January 2010 to 2011,which were 15 males and 13 females; a mean age 40 years (ranged,18-53years),according ARCO stages:eight hips stage Ⅱ a,ten b,nine Ⅲ a,nine b,adopt grafting Implantation head.The Harris hip score VAS pre-and post-operation was...
We studied whether enriched environment (EE), a classic epigenetics paradigm, can prevent cellular plasticity damage caused by chronic sleep deprivation (SD).We performed SD in mice modified multi-platform method (MMPM). Mice the group were deprived of for 18 h day. In addition, half exposed to EE stimuli 6 per Immunostaining analyzed neurogenesis and neural progenitor cell-differentiated phenotypes hippocampal dentate gyrus (DG) region.At 13 weeks, compared with control group, severely...
Sleep plays an important role in the learning process and memory consolidation, sleep deprivation (SD) leads to inadequate consolidation brain development plasticity. SD increases β-amyloid levels while impairing cognitive function. We explored effect of enriched environment (EE) on transporter protein LRP1 receptor for advanced glycosylation end-products (RAGE) expression chronic deprived mice. randomly divided mice into four groups (n = 10), standard group (Ctrl group), (SD intervention...
Acute myocardial infarction (AMI) is a serious disease with high mortality. Stromal cell-derived factor 1 (SDF-1) can recruit circulating progenitor cell populations into damaged tissues. Bone marrow mesenchymal stem cells (BMSCs) have variety of cellular functions. We studied the ability SDF-1 to repair ischemia/reperfusion injury (IRI)-induced heart via regulating BMSCs proliferation in rats. Mouse were isolated and expanded. Cell apoptotic factors analyzed. The rats assigned control...