A5101714130- Liver Disease Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
- Tryptophan and brain disorders
- Piperaceae Chemical and Biological Studies
- Gout, Hyperuricemia, Uric Acid
- Advanced MRI Techniques and Applications
- Stress Responses and Cortisol
- Alzheimer's disease research and treatments
- Metal complexes synthesis and properties
- Medicinal Plants and Neuroprotection
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Alcohol Consumption and Health Effects
- Anesthesia and Pain Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Airway Management and Intubation Techniques
- Traditional Chinese Medicine Analysis
- Metal-Organic Frameworks: Synthesis and Applications
- Cholinesterase and Neurodegenerative Diseases
- Respiratory Support and Mechanisms
- Lipid metabolism and disorders
- Neuroendocrine regulation and behavior
- Medical Imaging Techniques and Applications
- Cardiac Arrest and Resuscitation
- Healthcare and Venom Research
Tianjin First Center Hospital
2023-2025
Tianjin Medical University
2023-2025
Nankai University
2023-2025
Shenzhen Institutes of Advanced Technology
2022-2024
Chinese Academy of Sciences
2022-2024
Chang Gung Memorial Hospital
2024
Beijing University of Chinese Medicine
2022-2024
Zhejiang Chinese Medical University
2023
Chongqing University of Technology
2022
Liaoning Normal University
2006-2020
In the present study, antidepressant-like effects of piperine (PIP) and its derivative, antiepilepsirine (AES), were investigated in two depressive models: forced swimming test (FST) tail suspension (TST). To further explore mechanisms underlying their activities, brain monoamine levels oxidase A B (MAO-A MAO-B) activities also determined. The research results for first time indicated that after weeks chronic administration, PIP AES at doses 10-20 mg/kg significantly reduced duration...
Background: Maslinic acid (MA), a pentacyclic triterpenoid compound derived from leaves and fruits of Olea europaea, bears multi-pharmacological properties. Our previous studies found that MA exerted cardioprotective effect by modulating oxidative stress, inflammation, apoptosis during myocardial ischemia-reperfusion injury (MIRI). Nevertheless, data regarding the anti-ferroptosis effects on MI/RI remains unidentified Aim Study: This study aimed to explore ferroptosis induced MI/RI, with...
Background: Metabolic syndrome (MetS) is a prevalent health condition in Taiwan that places individuals at higher risk of cardiovascular disease, diabetes, and stroke. Therefore, the identification factors associated with MetS crucial. The aim this study was to investigate association uric acid Taiwanese community middle-aged elderly population. Methods: This cross-sectional enrolled residents aged 50–90 years living one community. All subjects received standardized personal interview,...
Two transition metal (Zn, Cu) complexes with a Schiff base (salicylideneglycine) and 1,10-phenanthroline: (C9H7NO3)Zn(C12H8N2)(H2O) (1) (C9H7NO3)Cu(C12H8N2) (2) have been synthesized characterized, including crystal structures, spectral characterization, thermogravimetric analyses quantum chemistry calculations. X-ray crystallographic analysis shows the zinc to be six-coordinate mode, forming slightly distorted octahedral geometry. The structure of 2 can evaluated by Addison distortion index...
Purpose. As one of the most common chronic liver diseases, metabolic dysfunction-associated fatty disease (MAFLD) had different prognoses between mild and moderate-severe levels. Serum uric acid to serum creatinine ratio (sUA/Cr) can reflect overall status body. To explore a convenient indicator screen MAFLD distinguish severity disease, this study analyzed correlation sUA/Cr MAFLD. Methods. 228 participants were enrolled divided into 2 groups, including non-MAFLD group group, based on...
Two new isostructural copper(II)–zinc(II) complexes, [CuZnLBr2] (1) and [CuZnLCl2] (2) (H2L = N,N′-bis(4-methoxysalicylidene)cyclohexane-1,2-diamine), have been synthesized characterized by elemental analyses, infrared spectroscopy, single-crystal X-ray diffraction. Both complexes crystallize in the P-1 space group. The Cu each complex is four-coordinate square planar with two imines phenolates of L. Zn tetrahedral L halides (Br for 1 Cl 2). superoxide dismutase (SOD) activity indicates that...
Introduction: Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic disease, which usually associated with type 2 diabetes mellitus (T DM) and obesity. However, incidence of MALFD in non-obese individuals without T DM increasing, pathogenesis unclear. Serum uric acid to creatinine ratio (sUA/Cr) can reflect overall metabolic status. This study aims observe association between sUA/Cr MAFLD DM. Methods: A total 21,996 were included this study. The subjects...
Accurate and reproducible assessment of left ventricular (LV) volumes is important in managing various cardiac conditions. However, patients are required to hold their breath multiple times during data acquisition, which may result discomfort restrict motion, potentially compromising the accuracy detected results. Accelerated imaging techniques can help reduce number holds needed, improving patient comfort reliability LV assessment. This study aimed prospectively evaluate feasibility with a...
According to the latest consensus statement, fatty liver complicated by specific metabolic abnormalities can be diagnosed as dysfunction-associated disease (MAFLD) in nonobese patients without type 2 diabetes mellitus (T2DM). However, hyperuricemia (HUA), a manifestation of disorders, is excluded from diagnostic criteria. This study explored association between HUA and MAFLD T2DM. A total 28,187 participants were recruited Examination Center China-Japan Friendship Hospital 2018 2022 divided...
This study aims to evaluate pharmacological and behavioral interventions for the treatment of fatigue in Parkinson's disease (PD) patients.We systematically searched PubMed, PsycINFO, Web Science, EMBASE, CNKI, Wan fang, VIP up July 31, 2022. We used Revman 5.3 software meta-analysis. The outcomes included Fatigue Severity Scale (FSS) (PFS). mean difference (MD) 95% confidence intervals (CI) were collected or calculated.Thirteen randomized controlled trials (RCTs) with a total 1758 patients...
We propose VRL3, a powerful data-driven framework with simple design for solving challenging visual deep reinforcement learning (DRL) tasks. analyze number of major obstacles in taking approach, and present suite principles, novel findings, critical insights about DRL. Our has three stages: stage 1, we leverage non-RL datasets (e.g. ImageNet) to learn task-agnostic representations; 2, use offline RL data limited expert demonstrations) convert the representations into more task-specific 3,...
Objective Metabolic dysfunction-associated fatty liver disease (MAFLD) affects 25% of the population without approved drug therapy. According to latest consensus, MAFLD is divided into three subgroups based on different diagnostic modalities, including Obesity, Lean, and Type 2 diabetes mellitus (T DM) subgroups. This study aimed find out optimum non-invasive metabolism-related indicators respectively predict its Design 1058 Chinese participants were enrolled in this study. Anthropometric...