A5068196186- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Advances in Oncology and Radiotherapy
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Nuclear Physics and Applications
- Boron Compounds in Chemistry
- Lung Cancer Diagnosis and Treatment
- Effects of Radiation Exposure
- Breast Cancer Treatment Studies
- Radiation Detection and Scintillator Technologies
- Health and Medical Research Impacts
- Radiology practices and education
- Management of metastatic bone disease
- Radiation Effects and Dosimetry
- Biomedical and Engineering Education
- Diversity and Career in Medicine
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Cancer Studies
- Radiopharmaceutical Chemistry and Applications
- Innovations in Medical Education
- Glioma Diagnosis and Treatment
- Atomic and Subatomic Physics Research
- Advanced X-ray and CT Imaging
- Endometrial and Cervical Cancer Treatments
Wayne State University
2015-2024
The Barbara Ann Karmanos Cancer Institute
2015-2024
American Society for Radiation Oncology
2023
Wayne State College
2018
Michigan State University
2012
Vanderbilt University Medical Center
2012
The University of Texas MD Anderson Cancer Center
2012
Harper University Hospital
1999-2009
Radiation Oncology Associates
2002-2004
TetraLogic Pharmaceuticals (United States)
2001
AAPM Task Group 119 has produced quantitative confidence limits as baseline expectation values for IMRT commissioning. A set of test cases was developed to assess the overall accuracy planning and delivery treatments. Each uses contours targets avoidance structures drawn within rectangular phantoms. These tests were planned, delivered, measured, analyzed by nine facilities using a variety systems. facility had passed Radiological Physics Center credentialing IMRT. The agreement between...
Visualization and detection of early-stage gynecological malignancies represents a challenge for imaging due to limiting factors including tissue accessibility, device ease use, accuracy modalities. In this work, we introduce miniaturized phased-array ultrasound photoacoustic endoscopic probe which is capable providing structural, functional, molecular data the characterization gynecologic disease. The proposed consists 64-element transducer coupled fiber-optic light delivery system...
The cone-beam computed tomography (CBCT) imaging modality is an integral component of image-guided adaptive radiation therapy (IGART), which uses patient-specific dynamic/temporal information for potential treatment plan modification. In this study, offline process the IGART framework has been implemented that consists deformable image registration (DIR) and its validation, dose reconstruction, accumulation verification. This study compares differences between planned estimated delivered...
Spine SBRT involves the delivery of very high doses radiation to targets adjacent spinal cord and is most commonly delivered in a single fraction. Highly conformal planning accurate such plans imperative for successful treatment without catastrophic adverse effects. End–to‐end testing an important practice evaluating entire process from simulation through delivery. We performed end‐to‐end set representative spine planned using four different systems (TPSs) evaluate various capabilities each....
Since the publication of AAPM Task Group (TG) 148 on quality assurance (QA) for helical tomotherapy, there have been many new developments tomotherapy platform involving treatment delivery, on-board imaging options, motion management, and planning systems (TPSs). In response to a need guidance control (QC) QA these technologies, Therapy Physics Committee commissioned TG 306 review changes make recommendations related technology updates. The specific objectives this were (1) update, as...
There are numerous commercial radiotherapy systems capable of delivering single fraction spine radiosurgery/SBRT. We aim to compare the capabilities several these deliver this treatment when following standardized criteria from a national protocol. Four distinct target lesions representing various case presentations metastases were contoured in both thoracic and lumbar an anthropomorphic SBRT phantom. Single radiosurgery/SBRT plans designed for each with our platforms. Plans prescribed 16 Gy...
Several adverse effects have been reported in the literature associated with total body irradiation (TBI). Reports of TBI primarily drawn from single-institution retrospective analyses. We report, to our knowledge, one largest cohorts patients treated using multiple preparative chemotherapy and radiation regimens.A chart review was performed for all 705 at institution 1995 2017. Based on availability records, 622 (88%) had sufficient evaluable documentation analysis. Patients received 1 4...
There is a clear need for established standards medical physics residency training. The complexity of techniques in imaging, nuclear medicine, and radiation oncology continues to increase with each passing year. It therefore imperative that training requirements competencies are routinely reviewed updated reflect the changing environment hospitals clinics across country. In 2010, AAPM Work Group on Periodic Review Medical Physics Residency Training was formed charged updating Report Number...
The purpose of this work is to present the results a margin reduction study involving dosimetric and radiobiologic assessment cumulative dose distributions, computed using an image guided adaptive radiotherapy based framework. Eight prostate cancer patients, treated with 7–9, 6 MV, intensity modulated radiation therapy (IMRT) fields, were included in study. workflow consists cone beam CT (CBCT) localization, deformable registration CBCT simulation datasets (SIM-CT), reconstruction...
The contribution of radiation oncology to the future cancer treatment depends significantly on our continued clinical progress and research advancements. Such relies multidisciplinary collaboration among oncologists, medical physicists radiobiologists. Cultivating collaborative educational opportunities these three disciplines further investing in infrastructure used train both clinicians researchers will therefore help us improve care. This article evaluates success a short-term environment...
This study investigates the influence of multileaf collimator (MLC) leaf width on intensity modulated radiation therapy (IMRT) plans delivered via segmented (SMLC) technique. IMRT were calculated using Corvus treatment planning system for three brain, prostate, and pancreas cases widths 0.5 1 cm. Resulting differences in plan quality complexity are presented here. Plans a cm chosen over seven out nine based clinical judgment. Conversely, optimization results revealed superior objective...
Purpose To experimentally simulate IMRT delivery using two human cell models in vitro and test the hypothesis that a loss effective dose resulting from prolongation of megavoltage x‐ray treatment time would be greatly reduced corresponding simulations higher‐LET radiation. Methods The effect prolonging fraction was investigated PC‐3 prostate HGL21 glioblastoma tumor lines. Cells were irradiated with x rays conventional linear accelerator or neutrons clinical radiotherapy beam maintained at...
A commercial electron Monte Carlo (eMC) dose calculation algorithm has become available in Eclipse treatment planning system. The purpose of this work was to evaluate the eMC and investigate clinical implementation beam modeling performed for energies 6, 9, 12, 16, 20 MeV a Varian Trilogy all applicator sizes accuracy evaluated homogeneous water phantom, solid phantoms containing lung bone materials, an anthropomorphic phantom. In addition, compared between pencil (PB) algorithms same system...
Purpose: Both spatial and biological information are necessary in order to perform true optimization of a treatment plan for predicting clinical outcome. The goal this work is develop an enhanced evaluation tool which incorporates parameters retains dose information. Methods: A software system developed provides with novel combination features. It hyper‐radiosensitivity using the induced‐repair model applies new concept convolution filter (DCF) simulate wash‐out effects due cell migration,...
The purpose of this work is to develop metrics for evaluation medical physics graduate student performance, assess relationships between success and other quantifiable factors, determine whether performance can be accurately predicted by admissions statistics. A cohort 108 students from a single institution were rated after matriculation based on final scores in specific courses, first year Grade Point Average (GPA), the program exit exam, oral review sessions, faculty rating. Admissions...
We investigate the relationship between various parameters in Monaco MLC model and dose calculation accuracy for an Elekta Agility MLC. The vendor-provided modeling procedure - completed first with external vendor participation then exclusively in-house was used combination our own procedures to several sets of determine their effect on distributions point-dose measurements. Simple plans provided were elucidate specific mechanical characteristics MLC, while ten complex treatment five IMRT...
PurposeValue-based care is increasingly informing treatment decisions in radiation oncology. Although reimbursement differences have been examined for accelerated whole breast irradiation (AWBI) and conventional (CWBI), the cost of delivery poorly understood. This article describes our experience evaluating costs altered fractionation early-stage cancer using a time-driven activity-based costing (TDABC) model.Methods MaterialsProcess maps were developed 2 regimens, AWBI (42.5 Gy 16 fractions...
A dual miniature tissue‐equivalent proportional counter (TEPC) system has been developed to facilitate microdosimetry for Boron Neutron Capture Therapy (BNCT). This designed specifically allow the analysis of single event charged particle spectrum in phantom high intensity BNCT beams and provide this microdosimetric information with excellent spatial resolution. Paired A‐150 ‐loaded TEPCs 12.3 mm 3 collecting volumes have constructed. These more accurate neutron dosimetry than current...