Xingru Zhao

ORCID: 0000-0002-9607-0227
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About
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Research Areas
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Ferroptosis and cancer prognosis
  • Phytochemical compounds biological activities
  • Radiomics and Machine Learning in Medical Imaging
  • Medical Imaging and Pathology Studies
  • Dental Radiography and Imaging
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Bioactive Compounds and Antitumor Agents
  • Respiratory Support and Mechanisms
  • Oral microbiology and periodontitis research
  • Phytochemistry and Bioactive Compounds
  • Dental Health and Care Utilization
  • Nutrition, Genetics, and Disease
  • Nutritional Studies and Diet
  • Tracheal and airway disorders
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Asthma and respiratory diseases
  • Medical Imaging Techniques and Applications
  • Long-Term Effects of COVID-19
  • Cancer, Lipids, and Metabolism
  • Genetic Associations and Epidemiology

Henan Provincial People's Hospital
2019-2025

Zhengzhou University
2019-2025

Nanjing University of Chinese Medicine
2024

Zhengzhou People's Hospital
2022

China has implemented the "tiered medical services" policy since 2015, while there is a paucity of data evaluating current status chronic obstructive pulmonary disease (COPD) management under system. Characteristics and treatments from 11,905 COPD patients in 88 hospitals across different tiers were included analyzed. We assessed statistical significance differences by one way analysis variance (ANOVA) for continuous variables with chi-squared test categorical variables. Patients primary...

10.1038/s41598-024-85010-x article EN cc-by-nc-nd Scientific Reports 2025-01-04

The relationship between periodontitis and cardiovascular disease (CVD) has been extensively studied, but the role of biological aging in this remains poorly understood. This study is dedicated to investigating effect on incidence CVD elucidating potential mediating aging. Furthermore, will seek elucidate causal association periodontitis, CVD, We included 3269 participants from National Health Nutrition Examination Survey (2009–2014) with diagnostic information composite events. Biological...

10.1186/s13148-024-01732-9 article EN cc-by-nc-nd Clinical Epigenetics 2024-08-24

Background Despite substantial progress in reducing the global burden of chronic obstructive pulmonary disease (COPD), traditional methods to promote understanding and management COPD are insufficient. We developed an innovative model based on internet things (IoT) for screening primary healthcare (PHC). Methods Electronic questionnaire IoT-based spirometer were used screen residents. defined individuals with a score 16 or higher as high-risk population, was diagnosed according 2021 Global...

10.1136/bmjresp-2023-001954 article EN cc-by-nc BMJ Open Respiratory Research 2024-04-01

Abstract Background Calotropis procera leaf is one of the plants commonly utilized in phytomedicine Nigeria. The present investigation explored use extracts on cell viability and apoptosis respectively. In this study, expression Cluster differentiation 146 (CD146) blood lung cancer patients regulatory T cells (Tregs) was determined. antioxidant anti-proliferative effects methanol Caloropis H1299 were investigated. Methods From flow cytometry, CD146+ evaluated using healthy patient,...

10.1186/s40816-021-00289-x article EN cc-by Clinical Phytoscience 2021-06-07

<title>Abstract</title> Background The relationship between periodontitis and cardiovascular disease (CVD) has been extensively studied, but the role of biological aging in this remains poorly understood. This study is dedicated to investigating effect on incidence CVD elucidating potential mediating aging. Furthermore, will seek elucidate causal association periodontitis, CVD, Methods We included 3269 participants from National Health Nutrition Examination Survey (2009–2014) with diagnostic...

10.21203/rs.3.rs-4734668/v1 preprint EN cc-by Research Square (Research Square) 2024-08-13

Computed tomography images are easy to misjudge because of their complexity, especially solitary pulmonary nodules, which diagnosis as benign or malignant is extremely important in lung cancer treatment. Therefore, there an urgent need for a more effective strategy diagnosis. In our study, we aimed externally validate and revise the Mayo model, new model was established.A total 1450 patients from three centers with nodules who underwent surgery were included study divided into training,...

10.1097/cm9.0000000000001507 article EN cc-by-nc-nd Chinese Medical Journal 2021-06-15

Abstract Background We aimed to comprehensively analyze the clinical value of immune-related eRNAs-driven genes in lung adenocarcinoma (LUAD) and find potential biomarkers for prognosis therapeutic response improve survival this malignant disease. Materials methods Pearson’s correlation analysis was performed identify genes. Cox regression least absolute shrinkage selection operator (LASSO) analyses were used construct prognostic risk signature. Gene Ontology (GO) Kyoto Encyclopedia Genes...

10.1007/s00432-024-05687-5 article EN cc-by Journal of Cancer Research and Clinical Oncology 2024-04-11

<title>Abstract</title> Introduction: Stroke is an acute cerebrovascular disease that seriously affects lifespan, and aging generally considered important risk factor for stroke. This study aimed to explore the association between biological stroke using well-validated measures of aging. Methods We employed methods Klemera-Doubal (KDMAge) phenotypic age (PhenoAge) as alternative in National Health Nutrition Examination Survey (NHANES) from 1999 2018. In order analyze data, we logistic...

10.21203/rs.3.rs-4994277/v1 preprint EN cc-by Research Square (Research Square) 2024-10-22

To the Editor: Transthoracic needle aspiration (TTNA) and bronchoscopy have been preferred methods for sampling of pulmonary nodules suspected lung cancer. However, despite having a higher diagnostic accuracy, TTNA has associated with high rate pneumothorax. Moreover, conventional low pneumothorax exhibited yield peripheral nodules, particularly <2 cm in size or those without bronchus leading directly to them. Thus, Herth et al[1] developed novel technique called bronchoscopic...

10.1097/cm9.0000000000002355 article EN cc-by-nc-nd Chinese Medical Journal 2023-05-10

10543 Background: Outcomes are suboptimal when molecularly-targeted therapies used in patient populations unselected for the molecular target. This pilot study examines correlation of positron emission tomography (PET) using 11C-labeled 4-N-(3-bromoanilino)-6,7-dimethoxyquinazoline (11C-PD153035), an imaging biomarker epidermal growth factor receptor (EGFR), with outcomes patients non-small cell lung cancer (NSCLC) treated EGFR tyrosine kinase inhibitor (TKI) erlotinib. Methods: Patients...

10.1200/jco.2011.29.15_suppl.10543 article EN Journal of Clinical Oncology 2011-05-20
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