A5023532155- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Dental Radiography and Imaging
- HIV/AIDS oral health manifestations
- Oral Health Pathology and Treatment
- Dental Implant Techniques and Outcomes
- Oral and gingival health research
- Nutrition and Health in Aging
- Dental Research and COVID-19
- Salivary Gland Disorders and Functions
- Sirtuins and Resveratrol in Medicine
- Periodontal Regeneration and Treatments
- Endodontics and Root Canal Treatments
- Nutritional Studies and Diet
- Cleft Lip and Palate Research
- Bone and Dental Protein Studies
- Temporomandibular Joint Disorders
- Cardiovascular Health and Risk Factors
- Dental Anxiety and Anesthesia Techniques
- Anorectal Disease Treatments and Outcomes
- Dental materials and restorations
- Colorectal and Anal Carcinomas
- Neuroendocrine regulation and behavior
- Autophagy in Disease and Therapy
- Neuroinflammation and Neurodegeneration Mechanisms
University of Hong Kong
2020-2025
Shanghai Jiao Tong University
2021-2024
Shanghai Ninth People's Hospital
2021-2024
Fuzhou University
2024
National Clinical Research Center for Digestive Diseases
2022-2024
Shanghai Stomatological Hospital
2024
Prince Philip Dental Hospital
2021-2023
National Clinical Research
2021
To assess the diagnostic utility of an oral rinse active matrix metalloproteinase-8 (aMMP-8) point-of-care test (POCT) for differentiating periodontal health, gingivitis, as well different stages and grades periodontitis.The aMMP-8 index was undertaken in 408 consecutive adults, followed by a full-mouth examination. The reference standard 2017 World Workshop classification diseases. Sensitivity, specificity, area under receiver operating characteristic curve (AUROC) were assessed.68.6%...
This randomized controlled clinical trial was designed to compare the accuracy of machine-vision (MV)-based dynamic navigation (DN)-assisted immediate implant placement with conventional freehand technique.A total 24 subjects requiring in maxillary anterior teeth were randomly assigned either control (freehand by an experienced surgeon, n = 12) or test group (MV-DN, 12). Implant platform, apex, angular, and depth deviations respect prosthetically guided digital planning differences insertion...
Assessment of biomarkers, specifically active matrix metalloproteinase-8 (aMMP-8), in saliva/oral rinses is a promising diagnostic approach for periodontal health and disease. Different oral fluids have specific advantages limitations. This study investigates the effect sampling different on accuracy an aMMP-8 point care test (POCT).Unstimulated whole saliva, first, second rinse were sequentially taken from 95 consecutive adults. was quantitatively determined with lateral flow immunoassay...
To describe periodontal and functional characteristics of subjects diagnosed with different stages periodontitis to associate measures masticatory function quality life stage.This was a cross-sectional study on convenience sample 214 seeking oral care in hospital setting. They received full-mouth intra-oral examination including dental charting by single calibrated examiner who also established the stage diagnosis. Subjects were assessed using OHIP-14, validated dysfunction questionnaire,...
To develop a multiclass non-clinical screening tool for periodontal disease and assess its accuracy differentiating health, gingivitis different stages of periodontitis.A cross-sectional diagnostic study on convenience sample 408 consecutive subjects was conducted by applying three index tests estimating features the health-disease spectrum: self-administered questionnaire, an oral rinse activated matrix metalloproteinase-8 (aMMP-8) point-of-care test (POCT) determination gingival bleeding...
ABSTRACT Aim Masticatory dysfunction due to tooth loss is a potentially modifiable risk for mortality, but the pathway behind that remains be investigated. This prospective study aimed examine role of diet and ageing in associations between chewing capacity long‐term mortality. Methods Data were obtained from participants (aged ≥ 20) National Health Nutritional Survey (NHANES 1999–2010, n = 22,900). The mortality follow‐up ended on 31 December 2019. Chewing was determined by number...
Previous studies have focused on the association of single vitamin intake with periodontitis. However, consumption vitamins is commonly in form mixtures. The relationship between multiple and prevalence periodontitis needs to be investigated. In this cross-sectional study, 8512 participants full-mouth periodontal examination records (vitamins A, B1, B2, B6, B12, C, D, E, K) data from US National Health Nutrition Examination Survey (NHANES, 2009-2014) datasets were included. GLM Bayesian...
To clinically validate a self-reported questionnaire for periodontal disease and assess its accuracy differentiating health different stages of periodontitis.A Chinese (Cantonese) version was prepared by translating validating the original English questions proposed Centers Disease Control Prevention/American Academy Periodontology (CDC/AAP). The utility CDC/AAP individual assessed against full-mouth examination. Periodontal case definition based on 2017 World Workshop classification...
To investigate the association of number natural teeth with overall dietary diversity and nutritional status in a nationally representative study among older adults China.A cross-sectional analysis was conducted community-dwelling aged 65 years or from Chinese Longitudinal Healthy Longevity Study. According to self-reported teeth, participants were categorized into ≥20, 10-19, 1-9 edentulous. Dietary score (DDS) constructed based on intake frequencies 10 food groups assessed by simplified...
To assess the accuracy of self-reported gingival bleeding on brushing (GBoB) for differentiating between periodontal health and disease explore optimal haemoglobin concentration that enables visual detection GBoB.Self-assessment GBoB was conducted in supervised sessions 408 consecutive adults. The levels saliva/toothpaste slurry (TPS) were analysed, followed by a full-mouth examination. Periodontal diagnoses made based 2017 classification diseases. Gingival inflammation defined as presence...
The relationship between periodontitis and cardiovascular disease (CVD) has been extensively studied, but the role of biological aging in this remains poorly understood. This study is dedicated to investigating effect on incidence CVD elucidating potential mediating aging. Furthermore, will seek elucidate causal association periodontitis, CVD, We included 3269 participants from National Health Nutrition Examination Survey (2009–2014) with diagnostic information composite events. Biological...
To report the 36-month follow-up of a trial comparing adjunct xenogenic collagen matrix (CMX) or connective tissue graft (CTG) to coronally advanced flaps (CAF) for coverage multiple adjacent recessions.125 subjects (61 CMX) with 307 recessions in 8 centres from parent were followed-up 36 months. Primary outcome was change position gingival margin. Multilevel analysis used centre, subject and tooth as levels baseline parameters covariates.No differences observed between randomized...
Bleeding on brushing (BoB) is an important sign of gingival inflammation. Recently, the use intelligent toothbrushes and oral health Apps has shown potential to improve periodontal health. In context introduction Internet things network power-driven in a supportive care programme, aim this study was (a) audit adoption retention new technology; (b) preliminarily assess feasibility gather data BoB associate them with clinical parameters.100 subjects different case diagnoses participating (SPC)...
Objective To analyse the microbiome composition of health and gingivitis in Chinese undergraduates with high-throughput sequencing. Methods Sequencing 16S rRNA gene amplicons was performed MiSeq system to compare subgingival bacterial communities from 54 subjects 12 periodontally healthy controls. Results A total 1,967,372 sequences representing 14 phyla, 104 genera, 96 species were detected. Analysis similarities (Anosim) test Principal Component (PCA) showed significantly different...
Abstract Aim Treatment of periodontitis, a chronic inflammatory disease driven by biofilm dysbiosis, remains challenging due to patients' poor performance and adherence the necessary oral hygiene procedures. Novel, artificial intelligence‐enabled multimodal‐sensing toothbrushes (AI‐MST) can guide practices in real‐time transmit valuable data clinicians, thus enabling effective remote monitoring guidance. The aim this trial was assess effect such system as an adjunct clinical practice...