A5075855363- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- HIV/AIDS drug development and treatment
- Autoimmune Neurological Disorders and Treatments
- Peripheral Neuropathies and Disorders
- Nutrition and Health in Aging
- COVID-19 Clinical Research Studies
- Cardiovascular Health and Disease Prevention
- Hepatocellular Carcinoma Treatment and Prognosis
- Diabetes and associated disorders
- Health and Well-being Studies
- Organ Transplantation Techniques and Outcomes
- Retinal and Optic Conditions
- Cardiac, Anesthesia and Surgical Outcomes
- Amino Acid Enzymes and Metabolism
- Cell death mechanisms and regulation
- Diet, Metabolism, and Disease
- Botulinum Toxin and Related Neurological Disorders
- Stroke Rehabilitation and Recovery
- Spinal Cord Injury Research
Hospital Fatuma Bourguiba Monastir
2023-2025
Cairo University
2011-2024
Children Cancer Hospital
2021
Center for HIV and Hepatogastroenterology
2018
Institute of Endemic Disease Control in Shandong Province
2013
Background Accurate distinction between stroke etiologic subtypes is critical for physicians to provide tailored treatment. The triglyceride-glucose (TyG) index, a marker of insulin resistance, has been associated with risk but its role in distinguishing remains unclear. We aimed assess the TyG index's ability differentiate cardioembolic (CE) from non-cardioembolic (NCE) strokes.
Background: Overweight and obesity are common illnesses that impact around one billion individuals worldwide, with a higher prevalence among women than males. The study's objectives were to determine the determinants of overweight students their knowledge on subject. Methods: A cross-sectional study was performed 500 intermediate high school (250 boys 250 girls) in classes 7-12 Duhok city, between November 12, 2023, December 6, 2023. Anthropometric measures taken, systematic questionnaire...
Liver stiffness measured by transient elastgraphy correlates with Hepatic vein pressure gradient, liver Stiffness value of 21 kpa predicts significant portal hypertension. Aim is to predict esophageal varices presence fibroscan and possible grading degree in HCV related cirrhotic patients.Thirty two patients were recruited, age > 18 years, BMI< 35, no history of: upper GI bleeding, hepatocellular carcinoma, abdominal collaterals, ascites. Patients underwent clinical examination, laboratory...
Hepatitis C virus (HCV) infection has major health impact worldwide and is a significant cause of chronic liver disease. In Egypt, HCV highly endemic (up to 15% the population); 91% patients are infected with genotype 4. Searching for new predictors response therapy mandatory decrease cost adverse effects current therapy.The aim this study was clarify usefulness serum leptin, adiponectin, insulin resistance (IR) as treatment in hepatitis 4 (HCVG4).One hundred HCVG4 who were candidates...
This study aim is to assess the prevalence of occult HCV infection among Egyptian patients with non alcoholic fatty liver disease (NAFLD) elevated AST and ALT, correlate presence severity disease. Patients Methods: After informed consent 27 elevateed enzymes diagnosed as NAFLD were examined for demographic, clinical, laboratory data Ultrasonography. Liver biopsy was done tested RNA in tissue. Genotyping using RFLP analysis PCR products 5'NCR positive cases. Results: tissue 11/27 (40.7%);...
Background and aim: Pancreatic cancer is the fourth leading cause of cancer-related death worldwide, with an overall 5-year survival <5% mainly due to presence advanced disease at time diagnosis. Therefore development valid biomarkers diagnose pancreatic in early stages urgent need. This study concerned sensitivity specificity serum ICAM 1 versus CA 19-9 differentiation between healthy subjects acohort patients chronic pancreatitis a focus on assessing validity diagnosis cancer. Methods: A...
Background and aim. DNA methylation plays a critical role in the control of important cellular processes. The present study assessed impact promoter (PM) some genes on antiviral response to therapy it's relation presence fibrosis HCV-4 infected patients from Egypt. Material methods. Clinical, laboratory histopathological data 53 who were subjected combined collected; classified according their treatment status. profiles studied groups determined using following genes: APC, P14ARF, P73, DAPK,...
Hepatitis C virus (HCV) and diabetes mellitus (DM) are prevalent diseases worldwide, associated with significant morbidity, mortality, mutual association. The aims of this study were as follows: (i) find the prevalence DM among 71 806 Egyptian patients chronic HCV infection its effect on liver disease progression (ii) using data mining routine tests to predict hepatic fibrosis in diabetic infection.A retrospective multicentered included laboratory histopathological collected by National...
Objectives The introduction of direct acting antivirals (DAAs) has resulted in very high sustained virological response rates (SVR) patients with chronic hepatitis-C (CHC). There are still a minority who fails to achieve SVR. This study aims identify simple factors associated nonresponse DAAs using routine pretreatment workup. Methods A retrospective included 10 655 CHC were candidates for anti-viral therapy. Pretreatment demographics, laboratory results, ultrasonography and FIB-4were...
BACKGROUND AND RATIONALE FOR THE STUDY: Chronic HCV is a major cause of HCC development. Caspase Recruitment Domains (CARD) protein modules that regulate apoptosis and play an important role in various carcinogenesis processes, our aim to assess the possible CARD9, CARD10 only (COP) progression liver fibrosis pathogenesis Egyptian chronic patients.130 patients were recruited classified into 4 groups; I: HCV, II: active hepatitis, III: cirrhosis, IV: related HCC. Biochemical, virological...
We aimed at determination of the usefulness elastography [acoustic radiation force impulse (ARFI) and FibroScan] for evaluation nonalcoholic fatty liver disease (NAFLD) patients.A prospective cross-sectional study included 60 biopsy-proven NAFLD patients (mean age: 45 years) was carried out. All were subjected to lab works, biopsy, measurement stiffness by ARFI FibroScan steatosis controlled attenuation parameter (CAP). CAP measurements adjusted presence or absence diabetes according...
A polymorphism in the microsomal triglyceride transfer protein (MTP) is associated with hepatic fibrosis, and carriers showed higher levels of steatosis, hepatitis C virus (HCV) RNA advanced fibrosis. The aim this study was to MTP expression pattern HCV patients impact on response antiviral therapy.One hundred consecutive naive genotype 4 were recruited receive therapy, 40 control subjects also recruited. Demographic, laboratory, histopathology data collected. DNA isolated, samples subjected...
Abstract Background We evaluated the validity of some non-invasive scores and ultrasound findings to predict fibrosis steatosis in a cohort NAFLD patients who underwent liver biopsy. Ninety-seven were enrolled classified into NASH (66) simple groups (31) based on ROC curves constructed for Fibrosis-4 index (FIB4), aspartate aminotransferase platelet ratio ( APRI), score (NFS) prediction, also (hepatic index; HSI, fatty FLI) ultrasonographic subcutaneous visceral adipose tissue measurements...
Background: The present study aimed at evaluation of changes in estimated glomerular filtration rate (eGFR) among chronic Hepatitis C virus (HCV) patients with kidney disease (CKD) Stages 3–5 who were treated 12 weeks ritonavir-boosted paritaprevir, ombitasvir plus ribavirin.Methods: Changes renal functions compared across follow up time points (baseline, SVR4, and SVR8). Data on on-treatment adverse events (AEs), serious AEs, laboratory abnormalities, treatment discontinuation...
Survival of hepatocellular carcinoma (HCC) differs between regions and countries according to the different underlying factors degree standard care that enables early diagnosis management. Our aim was identify most potent predictive survival in Egyptian HCC patients receiving curative or palliative treatments.This retrospective study included 1302 attending multidisciplinary clinic, Cairo University, February 2009 December 2016. Clinical, laboratory, tumor characteristics, treatment data...