A5029093689- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Immune Cell Function and Interaction
- Research studies in Vietnam
- Posttraumatic Stress Disorder Research
- Migration, Health and Trauma
- T-cell and B-cell Immunology
- HIV/AIDS drug development and treatment
- Racial and Ethnic Identity Research
- HIV, TB, and STIs Epidemiology
- Vietnamese History and Culture Studies
- Infectious Diseases and Tuberculosis
- Substance Abuse Treatment and Outcomes
- Psychosomatic Disorders and Their Treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Hepatitis B Virus Studies
- Sex work and related issues
- Opioid Use Disorder Treatment
- Cytokine Signaling Pathways and Interactions
- Adolescent Sexual and Reproductive Health
- Immunotherapy and Immune Responses
- Maternal Mental Health During Pregnancy and Postpartum
- Child and Adolescent Psychosocial and Emotional Development
- Global Cancer Incidence and Screening
National Institute Of Hygiene And Epidemiology
2008-2024
Weatherford College
2023
Hoa Sen University
2021
Ministry of Health
2008-2015
Karolinska Institutet
2007-2011
Counseling Center
2004
Suffolk University
2001-2003
Harvard University
1997-1998
The purpose of this study was to determine in Vietnamese ex-political detainees newly arrived into the United States a) prevalence torture and psychiatric symptoms b) dose-effect relationships between cumulative experience posttraumatic stress disorder (PTSD) major depression. population included (N = 51) a comparison group 22). All respondents received culturally validated instruments with known psychometric properties including versions Hopkins Symptom Checklist-25 Harvard Trauma...
Abstract We examined the feasibility, acceptability, and therapeutic efficacy of a culturally adapted cognitive–behavior therapy (CBT) for twelve Vietnamese refugees with treatment‐resistant posttraumatic stress disorder (PTSD) panic attacks. These patients were treated in two separate cohorts six staggered onset treatment. Repeated measures Group × Time ANOVAs between‐group comparisons indicated significant improvements, large effect sizes (Cohen's d ) all outcome measures: Harvard Trauma...
The aim of this study was to investigate the validity Harvard Trauma Questionnaire (HTQ) and depression sub‐scale Hopkins Symptom Checklist‐25 (HSCL‐25) in screening for post‐traumatic stress disorder (PTSD) major depressive (MDD) among Vietnamese former political prisoners (POWs). population included POWs ( n = 51) who migrated Boston metropolitan area between January 1990 July 1992 under Special Released Re‐education Center Detainees Resettlement Program. criterion HTQ assessing PTSD...
The aim of this study was to examine the validity posttraumatic stress disorder (PTSD) among Vietnamese refugees. population included 74 refugees who had resettled in metropolitan Boston area. previously validated Harvard Trauma Questionnaire used assess traumatic events and trauma-related symptoms. number experienced positively correlated with severity PTSD-related symptoms population. Internal consistency estimates principal components analysis provided results that generally supported...
Background An estimated 120,000 HIV-associated cryptococcal meningitis (CM) cases occur each year in South and Southeast Asia; early treatment may improve outcomes. The World Health Organization (WHO) recently recommended screening HIV-infected adults with CD4<100 cells/mm3 for serum antigen (CrAg), a marker of infection, areas high CrAg prevalence. We evaluated prevalence cost-effectiveness this strategy northern southern Vietnam. Methods Serum samples were collected stored during 2009–2012...
ObjectiveTo study patterns and determinants of HIV prevalence risk-behaviour characteristics in different population groups four border provinces Viet Nam.Methods We surveyed during April-June 2002.We used stratified random-cluster sampling collected data concomitantly on status risk behaviours.The included were female sex workers (n = 2023), injecting drug users 1391), unmarried males aged 15-24 years 1885) categories mobile 1923).Findings found marked geographical contrasts prevalence,...
Background In countries where antiretroviral therapy has been available or is being rapidly expanded, the World Health Organization (WHO) recommends surveillance for transmitted HIV drug resistance (HIVDR) by threshold methods using specimens from antenatal clinics voluntary counselling and testing (VCT) sites. The aim of this study was to implement HIVDR survey in VCT sites Vietnam, prevalence high. Estimating infected population will enable appropriateness current regimens be assessed...
Surveying 60 Vietnamese patients with either current or past post-traumatic stress disorder, this article aims to phenomenologically characterize the syndrome of `hit by wind' in a multidimensional manner. This includes determining patient conceptualization profiling episodes suffered previous month, and presenting case vignettes. Eighteen (30%) at least one episode last month; all 18 had month that met panic attack criteria. For patients, 33 criteria were experienced month. these episodes,...
Abstract The aim of this study was to examine the validity posttraumatic stress disorder (PTSD) among Vietnamese refugees. population included 74 refugees who had resettled in metropolitan Boston area. previously validated Harvard Trauma Questionnaire used assess traumatic events and trauma‐related symptoms. number experienced positively correlated with severity PTSD‐related symptoms population. Internal consistency estimates principal components analysis provided results that generally...
Decreased memory B-cell maintenance during HIV-1 infection has been associated with the viraemia-induced accumulation of activated B cells, sensitive to Fas-mediated apoptosis. We aimed at clarifying whether other subsets might also be affected by an increased Fas expression in HIV-1-infected patients, and we studied possible contribution viraemia, lymphopenia or T-cell activation upregulation on cells. analysed have collaborative effects dysregulation modulatory molecules,...
To investigate the nature of recent HIV outbreaks among injecting drug users (IDUs) near Vietnam-China border, we genetically analyzed 24 HIV-positive blood specimens from 2 northern provinces Vietnam (Lang Son and quang Ninh) adjacent to China where IDUs were first detected in late 1996. Genetic subtyping based on gag (p17) env (C2/V3) sequences revealed that CRF01_AE is a principal strain circulating throughout Vietnam, including border. The majority Quang Ninh Lang showed significant...
Introduction Given the overlapping modes of transmission HIV, hepatitis B virus (HBV), and C (HCV), understanding burden relationship these infections is critical for an effective response. Representative data on among males who inject drugs (MWID), key high-risk population HIV in Vietnam, are currently lacking. Methods Data stored specimens from Vietnam's 2009-2010 Integrated Biologic Behavioral Survey, a cross-sectional study populations, were used this analysis. Plasma samples tested HBV,...
Interleukin-7 (IL-7) concentrations are increased in the blood of CD4+ T cell depleted individuals, including HIV-1 infected patients. High IL-7 levels might stimulate activation and, as we have shown earlier, can prime resting to CD95 induced apoptosis well. infection leads B abnormalities via (Fas) death receptor pathway and loss memory cells. Peripheral cells not sensitive for IL-7, due lack IL-7Ra expression on their surface; however, here demonstrate that high concentration...
Abstract. Thang PH, Ruffin N, Brodin D, Rethi B, Cam PD, Hien NT, Lopalco L, Vivar Chiodi F (Karolinska Institutet, Stockholm, Sweden; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam; San Raffaele Scientific Institute, Milan, Italy). The role IL‐1β in reduced IL‐7 production by stromal epithelial cells: a model for impaired T‐cell numbers the gut during HIV‐1 infection. J Intern Med 2010; 268 : 181–193. Objectives. Interleukin (IL)‐7 is key cytokine homeostasis. Stromal cells,...
PERSPECTIVE article Front. Immunol., 05 January 2012Sec. HIV and AIDS volume 2 - 2011 | https://doi.org/10.3389/fimmu.2011.00090
Introduction Increasing access to viral load (VL) monitoring is essential fight HIV epidemics. In remote settings in Vietnam, using dried blood spot (DBS) sampling for specimen collection could improve the situation. Here, people who inject drugs (PWID) represent many newly antiretroviral therapy (ART)-initiated patients. The goals of this evaluation were evaluate if VL and rate virological failure differed between PWID non-PWID. Methods Prospective cohort study patients initiated on ART...
Serum IL-7 levels correlate with T-cell depletion in HIV-infected individuals. In some patients, we observed that serum decreases upon progression to AIDS, suggesting a role for maintenance sporadic cases. Interestingly, were significantly lower stable long-term non-progressors (LTNP) than patients who lost the LTNP status 3-year follow-up (P < 0.001), indicating concentration might be valuable marker of state.
Abstract Introduction : In Vietnam, HIV testing services had been available only at provincial and district health facilities, but not the primary facilities. Consequently, access to limited especially in rural areas. 2012, Vietnam piloted decentralization integration of commune stations (CHSs). As a part this pilot, three‐rapid test algorithm was introduced CHSs. The objective study assess performance implementation quality assurance measures prevent misdiagnosis, Methods (Determine...
As CD8+CD28- T cells have been associated with dendritic and cell suppression, we analyzed whether an increase in numbers during HIV-1 infection could lead to impaired responses. In contrast the in-vitro generated suppressors, peripheral blood of both HIV-infected noninfected individuals promoted activation. The accumulation may thus contribute accelerated inflammatory reactions immune
A household-based population study interviewed 2,553 women and 1,984 men aged 15–49 years in urban (Ho Chi Minh City) rural (Thai Binh) provinces Viet Nam between July August 2005. The survey response rate was high—approximately 97% of households 93% adults overall, with a >92% acceptance HIV testing among eligible adults. unadjusted estimated prevalence 0.3% (confidence interval [CI]: 0.1–0.6%) Thai Binh 0.7% (CI: 0.3–1.3) Ho City (HCMC), compared the national estimates projections 0.352%...
Modelling suggests that early diagnosis and immediate antiretroviral therapy (ART) among key populations would have a substantial impact in reducing HIV transmission mortality Vietnam. An implementation research project of "test-and-treat" people who inject drugs (PWID) was developed to inform effective roll-out such interventions."Test-and-treat" offered PWID two high burden provinces, Thai Nguyen Thanh Hoa. The interventions comprised the offer biannual testing ART, irrespective CD4 count....