A5053332840- Celiac Disease Research and Management
- Microscopic Colitis
- Gastrointestinal disorders and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Helicobacter pylori-related gastroenterology studies
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- Digestive system and related health
- Galectins and Cancer Biology
- Esophageal and GI Pathology
- Immunodeficiency and Autoimmune Disorders
- Lymphatic Disorders and Treatments
- Intestinal Malrotation and Obstruction Disorders
- Multiple and Secondary Primary Cancers
- Microbial Metabolites in Food Biotechnology
- Gastroesophageal reflux and treatments
- Pancreatic and Hepatic Oncology Research
- Eosinophilic Esophagitis
- Head and Neck Anomalies
- Liver Disease and Transplantation
- Abdominal Surgery and Complications
- Abdominal vascular conditions and treatments
- Diverticular Disease and Complications
St. Antonius Ziekenhuis
2008-2023
Amsterdam UMC Location Vrije Universiteit Amsterdam
2005-2009
In-Q-Tel
2009
Hy-Line (United States)
2007
Vrije Universiteit Amsterdam
2007
Center for HIV and Hepatogastroenterology
2006
Meander Medisch Centrum
2003-2005
This guideline presents recommendations for the management of coeliac disease (CD) and other gluten-related disorders both in adults children. There has been a substantial increase prevalence CD over last 50 years many patients remain undiagnosed. Diagnostic testing, including serology biopsy, should be performed on gluten-containing diet. The diagnosis is based combination clinical, serological histopathological data. In group children may made without biopsy if strict criteria are...
Coeliac disease may be regarded as refractory (RCD) when symptoms persist or recur despite strict adherence to a gluten-free diet. RCD subdivided into types I and II with phenotypically normal aberrant intraepithelial T-cell population, respectively. seems respond well azathioprine/prednisone therapy. is usually resistant any known therapy transition enteropathy-associated lymphoma (EATL) common.To provide further insight the development of EATL, by reporting on long-term survival risk EATL...
There is a need for consensus on the recommendations follow-up of children and adolescents with celiac disease. Objectives: To gather current evidence to offer management. Methods: The Special Interest Group Celiac Diseases European Society Paediatric Gastroenterology Hepatology Nutrition formulated ten questions considered be essential care. A literature search (January 2010–March 2020) was performed in PubMed or Medline. Relevant publications were identified potentially eligible studies...
OBJECTIVE Patients with refractory celiac disease can develop enteropathy-associated T-cell lymphoma (EATL) or ulcerative jejunitis. Double-balloon enteroscopy allows examination of the small bowel. We prospectively assessed value this technique in patients a tertiary referral center. METHODS Small bowel was performed total 21 consecutive for lesions like ulcerations (high risk). Biopsy specimens were taken from such and examined at three different levels scope insertion depth. Tissue...
Objective. Enteropathy-associated T-cell lymphomas (EATLs) are non-Hodgkin of the small bowel, which specifically associated with coeliac disease (CD). To our knowledge no studies have previously reported on overall incidence EATLs in general population. The aim this study was to investigate EATL and demographic characteristics patients Netherlands. Material methods. A survey nation-wide network registry histo- cytopathology reports Netherlands (PALGA) performed. We included all detected...
AIM:To evaluate cladribine [2-chlorodeoxyadenosine (2-CdA)] therapy in refractory celiac disease (RCD) Ⅱ. METHODS:An open-label cohort-study of RCD Ⅱ patients treated with 2-CdA was performed between 2000 and 2010.Survival rate, enteropathy associated T-cell lymphoma (EATL) occurrence, clinical course, histological immunological response rates were evaluated. RESULTS:Overall, 32 included a median follow-up 31 mo.Eighteen responded well to 2-CdA.Patients responsive had statistically...
Background Data are scarce on the efficacy and safety of motorized spiral enteroscopy (MSE). No data available utility this technique in patients with surgically altered gastrointestinal (GI) anatomy. We aimed to evaluate MSE suspected small-bowel disease, including those GI Methods A multicenter prospective observational, uncontrolled study evaluated consecutive pathology an indication for diagnostic and/or therapeutic intervention. Results total 170 (102 men; median age 64 years, range...
Refractory coeliac disease (RCD) is being currently defined as persisting or recurring villous atrophy with crypt hyperplasia and increased intra-epithelial lymphocytes in spite of a strict gluten-free diet for more than 12 months when severe symptoms necessitate intervention independently the duration dietary therapy. Two categories RCD are recognized: type I without aberrant T cells II detected by immunophenotyping intestinal mucosa. In contrast to patients high percentage cells, seem...
<h3>Objective</h3> The aim was to determine the prevalence of small-bowel neoplasia in asymptomatic patients with Lynch syndrome (LS) by video capsule endoscopy (VCE). <h3>Design</h3> After obtaining informed consent, proven gene mutation carriers aged 35–70 years were included this prospective multicentre study Netherlands. Patients previous surgery excluded. bowel preparation, VCE performed. videos read two independent investigators. If significant lesions detected, an endoscopic procedure...
Validated nonbiopsy methods to assure duodenal mucosal healing in celiac disease are lacking, yet ongoing injury is associated with anemia, osteoporosis, and lymphoma. Most providers utilize clinical data as surrogates of status avoid additional esophagogastroduodenoscopy. The reliability such predict recovery has been incompletely evaluated. aim this study was rigorously assess patterns histologic at follow-up correlate findings data. Gastrointestinal pathologists from 13 centers evaluated...
Refractory celiac disease (RCD) is being defined as persisting or recurring villous atrophy with crypt hyperplasia and increased intraepithelial lymphocytes (IELs) in spite of a strict gluten-free diet (GFD) for >12 months when severe symptoms necessitate intervention independent the duration GFD. RCD may not respond primarily secondarily to All other causes malabsorption must be excluded additional features supporting diagnosis CD looked for, including presence antibodies untreated state...
Coeliac disease (CD) is a chronic immune-mediated small intestine enteropathy precipitated by gluten in genetically predisposed individuals. Adult presentation often atypical and malabsorption of vitamins minerals common, with consequent disturbance bone metabolism. We aim to evaluate laboratory deficiencies related metabolism the relationship between severity histological damage degree mass loss at diagnosis CD.A retrospective cross-sectional study 176 adult coeliac patients was carried...
Wieke HM Verbeek*a, Marco WJ Schreursb, Otto J Visserc, B Mary E von Blombergd, Abdulbaqi Al-Tomae & Chris JJ Mulderfa VU University Medical Center, Department of Gastroenterology and Hepatology, PO Box 7057, 1007 MB, Amsterdam, The Netherlands. b Pathology, Immunological Laboratory, De Boelelaan 1117, 1081 HV, c Hematology, HV d e St Antonius Hospital, 2500, 3430 EM, Nieuwegein, f