A5045639442- Intracranial Aneurysms: Treatment and Complications
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and Carotid Artery Diseases
- Neurological Complications and Syndromes
- Cardiovascular Health and Disease Prevention
- Vascular Malformations Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Meningioma and schwannoma management
- Cerebrovascular and genetic disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Aortic Disease and Treatment Approaches
- Spinal Fractures and Fixation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Angiogenesis and VEGF in Cancer
- Oropharyngeal Anatomy and Pathologies
- Venous Thromboembolism Diagnosis and Management
- Head and Neck Surgical Oncology
- Surgical Simulation and Training
- Neurological Disease Mechanisms and Treatments
- Cerebrospinal fluid and hydrocephalus
- Spinal Hematomas and Complications
- Pharmacovigilance and Adverse Drug Reactions
University of Toyama
2016-2025
Toyama University Hospital
2011-2022
Neurological Surgery
2021
Stony Brook University
2021
Shinshu University
2021
Oxford University Press (United Kingdom)
2020
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2018
Kawasaki Hospital
2008
Background/Objectives: The accumulation of uric acid in arteriosclerotic plaques has recently attracted attention. Because the interaction between hyperuricemia and atherosclerosis is complex, details remain obscure. We aimed to elucidate clinical effect monosodium urate monohydrate (MSU) deposition on carotid plaques. Methods: This study enrolled 89 patients with MSU deposits were confirmed using Gomori’s methenamine silver staining endarterectomy (CEA) specimens. To evaluate macrophage...
Surgical revascularization is known to reduce the incidence of further ischemic and hemorrhagic events in patients with moyamoya disease, but majority previous studies report only short-term (< 5 years) outcomes. Therefore, this study authors aimed evaluate late (5-20 outcomes after superficial temporal artery middle cerebral (STA-MCA) anastomosis indirect bypass (encephalo-duro-myo-arterio-pericranial synangiosis [EDMAPS]).
OBJECTIVE Plaque composition, but not degree of stenosis, may play a key role in the development recurrent ischemic events patients with symptomatic mild (< 50%) carotid artery stenosis. This multicenter prospective cohort study was aimed to determine their clinical and radiological features evaluate benefits endarterectomy (CEA) for them. METHODS included 124 cerebrovascular or retinal ipsilateral Best medical therapy (BMT) administered all participants. CEA stenting implemented at each...
Background This study aimed to explore how clinical and radiological profiles of patients undergoing carotid endarterectomy (CEA) have changed over the past 40 years. Methods We included our three Japanese case series CEA in late 1980s ( n = 73), 2000s 142), 2010s 108). precisely compared patients’ demographics, features, findings, short- long-term outcomes among cohorts. was performed with general anesthesia, routine use an internal shunt tube, intraoperative monitoring using somatosensory...
This study was aimed to analyze the outer diameter of involved arteries in moyamoya disease, using three-dimensional (3D) constructive interference steady state (CISS) and direct surgical inspection. Radiological evaluation performed 64 patients with disease. As controls, six severe middle cerebral artery (MCA) stenosis 17 healthy subjects were also recruited. On 3D-CISS, quantified supraclinoid portion internal carotid (C1), horizontal portions MCA (M1) anterior (A1), basilar artery. The...
Abstract BACKGROUND Fragile, dilated moyamoya vessels are the main source of hemorrhagic stroke in disease (MMD). However, prevalence largely differs between Asian and western countries, although underlying pathophysiology has not been clarified. OBJECTIVE To systematically analyze difference collateral angioarchitectures Japanese European Caucasians with MMD. METHODS This study included 71 patients MMD, including (n = 41) 30). Using preoperative cerebral angiography, developments...
This study aimed to assess longitudinal changes in the collateral channels originating from lenticulostriate artery (LSA), posterior communicating (PCoA), and anterior choroidal arteries (AChA PChA, respectively) during disease progression and/or aging. The impact of on onset type was also examined.
Abstract BACKGROUND The grading system for moyamoya disease is not established. OBJECTIVE To assess the usefulness of a recently proposed stratifying clinical severity and predicting postoperative morbidity in adult disease. METHODS We investigated 176 hemispheres from 89 patients who were diagnosed with Japan. Their data analyzed using Berlin minor modifications. After summarizing numerical values digital subtraction angiography (1-3 points), magnetic resonance imaging (0-1 single-photon...
The mechanisms underlying acute cerebrovascular syndrome in patients with carotid artery stenosis remain unclear.To assess the relationships among infarct localization, hemodynamics, and plaque components.This prospective study included 38 resulting from ipsilateral stenosis. Cerebral localization was categorized into 3 patterns (cortical, border zone, mixed pattern). Carotid components were evaluated T1-weighted magnetic resonance imaging time-of-flight imaging. blood flow (CBF) reactivity...
The calibers of donor arteries can change dynamically after bypass surgery in patients with moyamoya disease (MMD). present study aimed to evaluate the cutoffs caliber changes associated good surgical revascularization and assess impact clinical factors potentially related development.