A5005302180- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Ultrasound and Hyperthermia Applications
- Cancer, Hypoxia, and Metabolism
- Drug Solubulity and Delivery Systems
- Sleep and Wakefulness Research
- Urinary Bladder and Prostate Research
- Ocular Infections and Treatments
- Sleep and related disorders
- Ocular Surface and Contact Lens
- Cardiovascular Conditions and Treatments
- Circadian rhythm and melatonin
- Wound Healing and Treatments
- Agriculture, Plant Science, Crop Management
- Comparative Animal Anatomy Studies
- Amphibian and Reptile Biology
- Antifungal resistance and susceptibility
- Curcumin's Biomedical Applications
- Neonatal Respiratory Health Research
- Aquaculture disease management and microbiota
- Diabetes Management and Research
- Supramolecular Self-Assembly in Materials
- Phytochemical and Pharmacological Studies
- Congenital heart defects research
- Agriculture and Biological Studies
Cairo University
2004-2025
This study aimed to formulate diacerein loaded terpene-enriched invasomes (DCN-TINV) fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A: cholesterol concentration (%w/v), B: ethanol volume (mL) and C: phosphatidylcholine: drug ratio as the studied factors. Invasomes were constructed using thin film hydration technique. Herein, percent entrapment efficiency (EE%), particle size (PS), poly-dispersity index (PDI) zeta potential (ZP) statistically...
This work aimed to prepare Terconazole loaded proniosomes (TCZ-PNS) utilizing modified coacervation technique for the management of fungal keratitis. (TCZ) is a potent antifungal with poor aqueous solubility posing intricacies in its incorporation ocular formulations. A 23 factorial design was adopted probe independent formulation variables including A: Lecithin: cholesterol ratio, B: Surfactant: ratio and C: Span® 80 contribution (% total SAA). The formulae, generated by design, were...
Abstract The current study is regarding the development and characterization of Darifenacin-loaded self-assembled liquid crystal cubic nanoparticles (LCCN). An anhydrous approach was used for preparation these using a hydrotropic agent (propylene glycol), with minimal energy input. Upon dispersion in aqueous medium, system successfully transformed to cubosomal counterpart as depicted by transmission electron micrographs. A Box-Behnken design optimize formulation variables, namely A: amount...
Abstract Background Wound management is a critical procedure in veterinary practice. A wound an injury that requires the body’s cells’ alignment to break down due external assault, such as trauma, burns, accidents, and diseases. Re-epithelization, extracellular matrix deposition, especially collagen, inflammatory cell infiltration, development of new blood capillaries are four features used evaluate healing process. Using natural extract for preferred avoid side effects synthetic drugs. The...
Purpose: Development of hyaluronic acid conjugated metformin-phospholipid sonocomplexes (HA-MPS), a biphasic complexation product compiled for enhancing both the lipophilicity and targeting potential Metformin (MET) to CD44 receptors on pancreatic cancer. Methods: MET was chemically (HA) via amide coupling reaction. Then, HA physically Lipoid™S100 ultrasound irradiation. A combined D-optimal design implemented statistically optimize formulation variables. The HA-MPS were characterized...
This study aims to prepare drotaverine hydrochloride superporous hydrogel hybrid systems (DSHH systems) prolong its residence time in the stomach, provide extended release and reduce frequency of administration. Drotaverine (DRH) is a spasmolytic drug that suffers from brief due intestinal hypermotility during diarrheal episodes associated with gastrointestinal colics resulting low bioavailability repeated dosing. Eight DSHH were prepared using gas blowing technique. The evaluated regarding...
Abstract This study aimed to prepare a combined self-nanoemulsifying and self-assembled cubic nanoparticles (SNE/SAC) lyophilized tablet eliciting biphasic release pattern escorted with enhanced bioavailability for drugs hampered slow dissolution poor absorption. The antimuscarinic Darifenacin hydrobromide (DRF) was selected as model drug used treat overactive bladder-associated nocturia. DRF-SNE/SAC prepared so that upon reconstitution mixture of DRF-loaded nanoemulsion dispersion is...
To study the normal distribution of arteries that supply spinal cord cat, a colored latex solution was injectedin aorta ten adult cats. The specimens were dissected to expose in this species. main arterialsupplments ventral and dorsal arteries. These along their courses receivedseveral radicular arose from vertebral, intercostal lumbar Comparing resultsobtained with those commonly described humans, it is clear domestic cat shows great similarity mostrespects. However, marked variability...