A5023776184- Congenital Heart Disease Studies
- Cardiovascular Syncope and Autonomic Disorders
- Congenital Diaphragmatic Hernia Studies
- Blood Pressure and Hypertension Studies
- Cardiovascular Issues in Pregnancy
- Congenital heart defects research
- Cardiac Structural Anomalies and Repair
- Hormonal Regulation and Hypertension
- Vascular anomalies and interventions
- Coronary Artery Anomalies
- Aortic Disease and Treatment Approaches
- Kawasaki Disease and Coronary Complications
- Connective tissue disorders research
- Pulmonary Hypertension Research and Treatments
- Mechanical Circulatory Support Devices
- Tracheal and airway disorders
- Hemoglobinopathies and Related Disorders
- Viral Infections and Immunology Research
- Renin-Angiotensin System Studies
- Mitochondrial Function and Pathology
- Cardiomyopathy and Myosin Studies
- Blood groups and transfusion
- Heart Failure Treatment and Management
- Inflammasome and immune disorders
- Renal and Vascular Pathologies
Maimonides Medical Center
2007-2024
University of Colorado Anschutz Medical Campus
2024
New York University
2023
Bellevue Hospital Center
2023
Long Island University
2023
Boston Children's Hospital
2006
NewYork–Presbyterian Hospital
1995-1996
Cornell University
1995-1996
Research advances over the past 30 years have confirmed a critical role for genetics in etiology of dilated cardiomyopathies (DCMs). However, full knowledge genetic architecture DCM remains incomplete. We identified candidate causal gene, C10orf71, large family with 8 patients by whole-exome sequencing. Four loss-of-function variants C10orf71 were subsequently an additional group of492 sporadic from 2 independent cohorts. was found to be intrinsically disordered protein specifically...
Introduction: Hypoplastic Left Heart Syndrome (HLHS) is the leading indication for heart transplant and most common cause of cardiovascular death in infants, yet our understanding immunologic alterations HLHS inadequate. In this study we aimed to (1) assess whether peripheral blood immune cells (PBMCs) from patients display a pro-inflammatory phenotype, (2) identify specific factors associated with inflammation HLHS, (3) investigate interaction between PBMCs cardiomyocytes. Methods: were...
Introduction Coronavirus disease 2019 (COVID-19) is known to cause cardiac abnormalities in adults. Cardiac are well-described multisystem inflammatory syndrome children, but effects children with acute COVID-19 less understood. In this multicenter study, we assessed the of among hospitalized (<21 years) admitted three large healthcare systems New York City. Methods We performed a retrospective observational study. examined electrocardiograms, echocardiograms, troponin, or B-type natriuretic...
Cervical aortic arch (CAA) and retro-aortic innominate vein (RAIV) are rare entities which can be associated with one another in a structurally normal heart. Less well recognized is the fact, that third entity may often present as well, since abnormalities common CAA. Hence, these three (CAA, RAIV, an anomaly - this case post-ductal coarctation) triad. We first prenatal diagnosis of triad explained by embryological origins discussed along instructive aspects management.
A 20-year-old woman presented with mental retardation and a history of stroke related to moyamoya disease at the age 8 years. She had cognitive impairment which became more pronounced after stroke. This patient’s parents were first cousins six close family relatives strokes in their 60s or 70s. The 16-year-old sister learning disability, chronic muscle pain, an ECG suggestive previous hypoxemic heart injury. two sisters similar dysmorphic facial appearance including prominent philtrum,...
Objectives: To explore the difference in ascending aortic dilatation between subgroups of bicuspid valve (BAV) patients with and without coarctation aorta (CoA). Methods: Our echocardiographic database (1993–2006) was searched for BAV CoA (Group A) B). Measurements at annulus, root, sinotubular junction, were obtained each patient, body surface area-adjusted Z-score values compared. Exclusion criteria included more than mild stenosis or regurgitation, previous balloon valvuloplasty, complex...