A5043790650- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Neonatal Health and Biochemistry
- Infant Nutrition and Health
- Congenital Anomalies and Fetal Surgery
- Tracheal and airway disorders
- Platelet Disorders and Treatments
- Respiratory Support and Mechanisms
- Urological Disorders and Treatments
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Cytomegalovirus and herpesvirus research
- Pediatric Hepatobiliary Diseases and Treatments
- Infant Development and Preterm Care
- Pneumonia and Respiratory Infections
- Intestinal Malrotation and Obstruction Disorders
- Orthopedic Infections and Treatments
- Acute Kidney Injury Research
- Respiratory viral infections research
- Multiple Sclerosis Research Studies
- Abdominal Trauma and Injuries
- Renal Diseases and Glomerulopathies
- Prenatal Substance Exposure Effects
- Methemoglobinemia and Tumor Lysis Syndrome
- Blood groups and transfusion
University of South Florida
2019-2024
Florida College
2023
United Hospital
2021
United Hospital Center
2021
Wichita State University
2021
University of Kansas
2021
Brookdale University Hospital and Medical Center
2021
Smt. N.H.L. Municipal Medical College
2021
Children's Hospital Central California
2021
University of Miami
2017-2019
The management practices of Respiratory Distress Syndrome (RDS) in the newborn have changed over time. We examine trends epidemiology, resource utilization, and outcomes (mortality bronchopulmonary dysplasia [BPD]) RDS preterm neonates ≤34 weeks gestational age (GA) United States.In this retrospective serial cross-sectional study, we used ICD-9 codes to classify infants GA between 2003 2014 from National Inpatient Sample as having or not. Trends prevalence defined by code (ICD9-RDS), length...
Hyperoxia plays a key role in the development of bronchopulmonary dysplasia (BPD), chronic lung disease preterm infants. Infants with BPD often have brain injury that leads to long-term neurodevelopmental impairment, but underlying mechanisms control BPD-induced impairment remain unclear. Our previous studies shown hyperoxia-induced rodents is associated inflammasome activation. Here, we tested hypothesis and mediated by activation, inhibition caspase-1, component inflammasome, attenuates...
To determine the trends in tracheostomy placement and resource use preterm infants less than or equal to 30 weeks gestational age (GA) with bronchopulmonary dysplasia (BPD) United States from 2008 2017.This was a retrospective, serial cross-sectional study using data NIS. Inclusion criteria were: GA weeks, hospitalization at 28 days of age, assignment International Classification Diseases, Ninth Revision, Clinical Modification (ICD9-CM) ICD10-CM codes for BPD tracheostomy. Trends utilization...
Background: Growth in preterm infants is compromised during the transition phase of nutrition, when parenteral nutrition (PN) volumes are weaned with advancing enteral (EN) feeds, likely due to suboptimal nutrient intakes this time. We implemented new PN guidelines designed maintain optimal and compared growth outcomes cohort a control group. Materials Methods: A chart review was conducted on born <32 weeks’ gestation, before (control group) after (study protocol neonatal intensive care...
Abstract Background Splenectomy is considered an effective treatment for immune thrombocytopenia (ITP) with 70–80% response rate. However, its current use limited in children ITP. It unclear if the rates of splenectomy have changed over time. Using a large nationally representative database, we aimed to study trends pediatric hospitalizations ITP, and factors associated during these encounters. Methods National (Nationwide) Inpatient Sample (NIS), international classification diseases (9th...
Bronchopulmonary dysplasia (BPD) remains the most common and serious chronic lung disease of premature infants. Severe BPD complicated with pulmonary hypertension (PH) increases mortality these Riociguat is an allosteric soluble guanylate cyclase stimulator approved by FDA for treating PH in adults. However, it has not been use neonates due to concern adverse effects on long bone growth. To address this we investigated if administration riociguat beneficial preventing hyperoxia-induced...
Although a growing body of evidence suggests that early transition to oral antimicrobial therapy is equally efficacious prolonged intravenous antibiotics for treatment acute pediatric osteomyelitis, little known about the trends in peripherally inserted central catheter (PICC) placements. Using national database, we examined incidence rates hospitalizations osteomyelitis United States from 2007 through 2016, as well PICC placement, length stay (LOS), and cost associated with these...
Objective Our objective was to determine whether objectively measured sleep-disordered breathing (SDB) during pregnancy is associated with an increased risk of adverse neonatal outcomes in a cohort nulliparous individuals. Study Design Secondary analysis the nuMom2b sleep disordered substudy performed. Individuals underwent in-home studies for SDB assessment early (6–15 weeks' gestation) and mid-pregnancy (22–31 gestation). defined as apnea-hypopnea index ≥5 events/h at either time point....
Infantile hypertrophic pyloric stenosis (IHPS) is the most common reason for abdominal surgery in infants; however, national-level data on incidence rate and resource use are lacking. We aimed to examine national trends hospitalizations IHPS its management United States from 2012 2016.We performed a retrospective serial cross-sectional study using National Inpatient Sample, largest health care database States. included infants aged ≤1 year assigned an International Classification of...
Objective. To determine if a positive result on pneumography, diagnosis of gastroesophageal reflux disease (GERD), or nontreatment those diagnosed with GERD antireflux medications predicts an increased recurrence risk apparent life-threatening event (ALTE) over the first 4 weeks follow-up. Methods. Secondary analysis prospective, observational study 300 infants ALTE. Results. The relative recurrent ALTE was 1.26 (95% confidence interval = 0.47-3.38) among abnormal versus normal 1.98...
OBJECTIVES: We examined the trends in rate of Henoch-Schönlein purpura (HSP) hospitalizations and associated resource use among children United States from 2006 through 2014. METHODS: Pediatric with HSP were identified by using International Classification Diseases, Ninth Revision, code 287.0 National Inpatient Sample. hospitalization was calculated US population as denominator. Resource determined length stay (LOS) hospital cost. used linear regression for trend analysis. RESULTS: A total...
To determine the causes, predictors, and trends of 30-day readmissions following hospitalizations for pediatric diabetic ketoacidosis (DKA) in United States (US) from 2010 to 2014.We used International Classification Diseases, ninth revision, Clinical Modification codes identify children with DKA aged 2 18 years National Readmission Database US. Patients who had readmission within 30 days after an index admission were included study. We combined similar diagnoses into clinically important...
Data from the academic medical centers in United States showing improvements survival of periviable infants born at 22 to 24 weeks GA may not be nationally representative since a substantial proportion preterm are cared for community hospital-based neonatal intensive care units. Our objective was examine national trends and other short-term outcomes among ≤24 gestational age (GA) 2009 2018.
Retinopathy of prematurity is a major cause morbidity in preterm infants but population-based studies to evaluate recent trends incidence the United States (US) are lacking. Moreover, previous did not include use anti-Vascular Endothelial Growth Factor medications. The objective was examine secular and treatment severe retinopathy (sROP) from 2009 2018.This population-based, serial cross-sectional study that utilized data National Inpatient Sample. inclusion criteria were with gestational...