A5003813624- Bipolar Disorder and Treatment
- Electroconvulsive Therapy Studies
- Schizophrenia research and treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Tryptophan and brain disorders
- Electrolyte and hormonal disorders
- Functional Brain Connectivity Studies
- Treatment of Major Depression
- Child and Adolescent Psychosocial and Emotional Development
- Coordination Chemistry and Organometallics
- Pharmacological Effects and Toxicity Studies
- Adolescent and Pediatric Healthcare
- Mental Health Treatment and Access
- Obsessive-Compulsive Spectrum Disorders
- Eating Disorders and Behaviors
- Cannabis and Cannabinoid Research
- Pregnancy and Medication Impact
- Epilepsy research and treatment
- Maternal and Perinatal Health Interventions
- COVID-19 Digital Contact Tracing
- Educational Technology and Assessment
- Fetal and Pediatric Neurological Disorders
- Sexuality, Behavior, and Technology
- COVID-19 and healthcare impacts
- Infant Health and Development
University of Ottawa
2022-2024
Ottawa Hospital
2022-2024
Royal Ottawa Mental Health Centre
2024
University of British Columbia
2019-2023
Vancouver General Hospital
2023
Ottawa Hospital Research Institute
2022
National Institute of Mental Health and Neurosciences
2012-2020
Bhopal Memorial Hospital & Research Centre
2017
Manipal Academy of Higher Education
2012
Kasturba Medical College, Manipal
2012
Background The Canadian Network for Mood and Anxiety Treatments (CANMAT) last published clinical guidelines the management of major depressive disorder (MDD) in 2016. Owing to advances field, an update was needed incorporate new evidence provide revised recommendations assessment MDD adults. Methods CANMAT convened a editorial group comprised academic clinicians patient partners. A systematic literature review conducted, focusing on reviews meta-analyses since 2016 guidelines....
Background: Several Western countries have established mother-baby psychiatric units for women with mental illness in the postpartum; similar facilities are however not available most low and medium income owing to high costs of such need specially trained personnel. Materials Methods: The first dedicated inpatient unit (MBU) was started Bengaluru, India, 2009 at National Institute Mental Health Neurosciences response growing needs mothers severe their infants. We describe unique challenges...
<h3>Importance</h3> Major depressive episodes in bipolar disorder are common and debilitating. Repetitive transcranial magnetic stimulation is well established the treatment of major disorder, intermittent theta burst (iTBS) protocol replacing conventional protocols because noninferiority reduced delivery time. However, iTBS has not been adequately studied and, therefore, its efficacy uncertain. <h3>Objective</h3> To determine whether to left dorsolateral prefrontal cortex (LDLPFC) safe...
Antidepressants are used to treat acute depression in patients with bipolar I disorder, but their effect as maintenance treatment after the remission of has not been well studied.We conducted a multisite, double-blind, randomized, placebo-controlled trial adjunctive escitalopram or bupropion XL compared discontinuation antidepressant therapy disorder who had recently depressive episode. Patients were randomly assigned 1:1 ratio continue antidepressants for 52 weeks switch placebo at 8 weeks....
Youth in vulnerable situations are known to have high rates of mental disorders but low help-seeking. Help-seeking is be influenced by health literacy (MHL), a key concept that important for the recognition and planning intervention.To explore MHL help-seeking patterns group young women an urban slum setting India.A total 337 between 16 19 years age belonging settings formed study sample. Two vignettes on depression self-harm were used assess: (a) disorder, (b) help-seeking, (c) knowledge...
Although dopamine is implicated in the pathophysiology of bipolar disorder (BD), precise alterations dopaminergic system remain unknown.To assess transporter (DAT) density striatum patients with BD current and recently remitted mania comparison to healthy control individuals its correlation severity manic symptoms.This cross-sectional study conducted a tertiary care referral center for mood disorders Vancouver, British Columbia, Canada, recruited 26 (9 mania; 17 mania) 21 matched...
Objective: Bipolar disorder (BD) is considered to be a common comorbid condition in subjects with obsessive-compulsive (OCD), but there limited literature on the prevalence of BD and its clinical correlates those primary diagnosis OCD.Methods: We studied sample consecutively registered outpatients attending specialty OCD clinic India over period 13 months. One hundred seventy-one patients were assessed systematically using structured semi-structured instruments.Results: The lifetime was 4%....
Objective: Lithium and valproate are commonly used either in monotherapy or combination with atypical antipsychotics maintenance treatment of bipolar I disorder; however, their comparative efficacy is not well understood. This study aimed to compare the lithium on mood stability antipsychotics. Methods: We performed a post hoc analysis using data from 52-week randomized double-blind, placebo-controlled trial, that recruited 159 patients recently remitted mania during adjunctive antipsychotic...
Aripiprazole, due to its partial agonist activity at the D2 receptors, is often recommended as drug of choice in patients who develop antipsychotic-induced hyperprolactinemia. We report a case female patient developed hyperprolactinemia while on treatment with aripiprazole. This agonistic aripiprazole could be dose related, and hence, higher doses, by itself can have dopamine antagonistic properties hence cause prolactin system abnormalities.
To report about delirium related to Cycloserine. Systematic assessment and management of a patient who developed during the course treatment for MDR-TB. An association was found with use Cycloserine development delirium. The this case is described. Patients MDR-TB receiving should be closely monitored neuropsychiatric side effects early recognition treatment.