Alexander K. T. Kirschner

ORCID: 0000-0002-9797-3073
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About
Contact & Profiles
Research Areas
  • Fecal contamination and water quality
  • Microbial Community Ecology and Physiology
  • Water Treatment and Disinfection
  • Vibrio bacteria research studies
  • Marine and coastal ecosystems
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Aquaculture disease management and microbiota
  • Bacteriophages and microbial interactions
  • Legionella and Acanthamoeba research
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Groundwater flow and contamination studies
  • Environmental DNA in Biodiversity Studies
  • Child Nutrition and Water Access
  • Antibiotic Resistance in Bacteria
  • Soil and Water Nutrient Dynamics
  • Gut microbiota and health
  • Wastewater Treatment and Nitrogen Removal
  • Urban Stormwater Management Solutions
  • Viral gastroenteritis research and epidemiology
  • Biosensors and Analytical Detection
  • Bacterial biofilms and quorum sensing
  • Protist diversity and phylogeny
  • Methane Hydrates and Related Phenomena
  • Mycobacterium research and diagnosis
  • Wastewater Treatment and Reuse

Medical University of Vienna
2016-2025

Karl Landsteiner University of Health Sciences
2018-2025

Interuniversity Cooperation Centre Water & Health
2015-2024

University of Veterinary Medicine Vienna
2023

TU Wien
2023

University of Oslo
2022

Institut für Hygiene und Umwelt
2019

University of Vienna
1997-2003

Summary The bacterioplankton diversity in large rivers has thus far been under‐sampled despite the importance of streams and as components continental landscapes. Here, we present a comprehensive dataset detailing along midstream D anube River its tributaries. Using 16 S rRNA ‐gene amplicon sequencing, our analysis revealed that bacterial richness evenness gradually declined downriver both free‐living particle‐associated communities. These shifts were also supported by beta analysis, where...

10.1111/1462-2920.12886 article EN Environmental Microbiology 2015-04-29

Global change has caused a worldwide increase in reports of Vibrio-associated diseases with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence human infections followed regional climatic trends outbreaks occurring during episodes unusually warm weather. Similar patterns were also observed affecting organisms such as fish, bivalves corals. Basic knowledge is still lacking the ecology evolutionary biology these bacteria well their virulence mechanisms. Current...

10.3389/fmicb.2015.00830 article EN cc-by Frontiers in Microbiology 2015-08-13

Legionella infections are among the most important waterborne with constantly increasing numbers of cases in industrialized countries, as a result aging populations, rising immunocompromised individuals and increased need for conditioned water due to climate change. Surveillance systems is based on microbiological culture-based techniques; however, it has been shown that high percentages populations not culturable. In past two decades, relevance such viable but non-culturable (VBNC)...

10.1016/j.watres.2018.01.058 article EN cc-by-nc-nd Water Research 2018-02-03

The global spread of antimicrobial resistance (AMR) in the environment is a growing health threat. Large rivers are particular concern as they highly impacted by wastewater discharge while being vital lifelines serving various human needs. A comprehensive understanding occurrence, and key drivers AMR along whole river courses largely lacking. We provide holistic approach studying spatiotemporal patterns hotspots antibiotic genes (ARGs) 2311 km navigable Danube River, combining longitudinal...

10.1016/j.watres.2024.121244 article EN cc-by Water Research 2024-01-31

Summary Spring water of two alpine karst aquifers differing in hydrogeology but nearby catchments were investigated for their bacterial population dynamics. Dolomite aquifer spring 1 (DKAS 1) represents a dolomitic‐limestone showing high average residence time and relative constant flow. Limestone 2 (LKAS 2) constitutes typical limestone with dynamic hydrological regime discharge. yielded constantly lower cell counts biomasses (median 15 × 10 6 cells l −1 0.22 µg C ) as the LKAS 63 1.1...

10.1111/j.1462-2920.2005.00810.x article EN Environmental Microbiology 2005-05-06

The abundance of virus-like particles in a backwater system the Danube River covered range 1.2 x 10(sup7) to 6.1 ml(sup-1) from 1992 1993. Measurements head diameters for these particles, all which were presumed be viruses, led four defined size classes, ranging <60 nm >150 nm. 60- <90-nm class contained largest fraction total (41%), followed by 90- <150-nm (33%). frequency classes was not significantly different between two years. bacteria with mature phages ranged 1 4% over...

10.1128/aem.61.10.3734-3740.1995 article EN Applied and Environmental Microbiology 1995-10-01

Aims: This study evaluated the applicability of standard faecal indicator bacteria (SFIB) for alpine mountainous water resources monitoring. Methods and Results: Escherichia coli, enterococci (ENTC) Clostridium perfringens were investigated by or frequently applied phenotypic genotypic methods in a broad range animal human sources large area. occurred only human, livestock carnivorous source groups relevant average concentrations (log 4·7–7·0 CFU g−1) but not herbivorous wildlife sources....

10.1111/j.1365-2672.2010.04788.x article EN Journal of Applied Microbiology 2010-06-08

Spread and persistence of antibiotic resistance pose a severe threat to human health, yet there is still lack knowledge about reservoirs resistant bacteria in the environment. We took opportunity Joint Danube Survey 3 (JDS3), world's biggest river research expedition its kind 2013, analyse samples originating from different sampling points along whole length river. Due high clinical relevance, we concentrated on characterization Pseudomonas spp. evaluated profiles which were isolated eight...

10.3389/fmicb.2016.00586 article EN cc-by Frontiers in Microbiology 2016-05-03

The microbial faecal pollution of rivers has wide-ranging impacts on a variety human activities that rely appropriate river water quality. Thus, detailed knowledge the extent and origin is crucial for watershed management to maintain safe use. In this study, levels were monitored by standard indicator bacteria (SFIB) along 2580 km stretch Danube, world's most international river, as well Danube's important tributaries. To track pollution, host-associated Bacteroidetes genetic marker qPCR...

10.1016/j.watres.2017.07.052 article EN cc-by-nc-nd Water Research 2017-07-22

This was a detailed investigation of the seasonal occurrence, dynamics, removal and resistance human-associated genetic Bacteroidetes faecal markers (GeBaM) compared with ISO-based standard indicator bacteria (SFIB), human-specific viral one phage in raw treated wastewater municipal domestic origin. Characteristics selected activated sludge treatment plants (WWTPs) from Austria Germany were studied detail (WWTPs, n = 13, connected populations 3 to 49000 individuals), supported by...

10.1016/j.watres.2015.12.031 article EN cc-by-nc-nd Water Research 2015-12-19

In a clinical setting it seems to be normal these days that relevant proportion or even the majority of different bacterial species has already one more acquired antibiotic resistances. Unfortunately, overuse antibiotics for livestock breeding and medicine also altered wild-type resistance profiles many in environmental settings. As matter fact, getting contact with resistant bacteria is no longer restricted hospitals. Beside food production, aquatic environment might play an important role...

10.1371/journal.pone.0165820 article EN cc-by PLoS ONE 2016-11-03

ABSTRACT Vibrio cholerae non-O1/non-O139 strains have caused several cases of ear, wound, and blood infections, including one lethal case septicemia in Austria, during recent years. All these had a history local recreational activities the large eastern Austrian lake Neusiedler See. Thus, monitoring program was started to investigate prevalence V. over Genetic analyses isolated revealed presence variety pathogenic genes, but no did we detect cholera toxin gene or toxin-coregulated pilus...

10.1128/aem.01739-07 article EN Applied and Environmental Microbiology 2008-02-02

Legionella pneumophila is known as the causative agent of Legionnaires' disease and free-living amoebae (FLA) can serve vehicles for legionellae. The aim this study was to screen industrial waters occurrence FLA their co-occurrence with A total 201 water samples, including 129 cooling 72 process waters, 30 lubricants were included in study. Treated screened periodically, pre post treatment. Altogether, 72.6% samples positive FLA, acanthamoebae being most prevalent (in 23.9% samples) followed...

10.1016/j.ejop.2014.04.002 article EN cc-by-nc-nd European Journal of Protistology 2014-05-13

Abstract DNA aptamers generated by cell-SELEX against bacterial cells have gained increased interest as novel and cost-effective affinity reagents for cell labelling, imaging biosensing. Here we describe the selection identification of using a combined approach based on cell-SELEX, state-of-the-art applications quantitative real-time PCR (qPCR), next-generation sequencing (NGS) bioinformatic data analysis. This is demonstrated Enterococcus faecalis ( E. ), which served target in eleven...

10.1038/s41598-020-77221-9 article EN cc-by Scientific Reports 2020-12-01

In Serbia less than 13% of collected municipal wastewaters is being treated before their release in the environment. This includes all wastewater discharges from Belgrade (capital city Serbia; population 1,700,000). Previous research has identified impacts raw on Danube River, and this study investigated if such also provided a pathway for SARS-CoV-2 RNA material. Samples were during most critical circumstances that occurred so far within COVID-19 pandemics Serbia. Grab composite samples...

10.1016/j.scitotenv.2021.146967 article EN cc-by-nc-nd The Science of The Total Environment 2021-04-08

Cryptosporidium parvum is a pathogen causing gastrointestinal infections, occasionally leading to death in immunocompromised individuals. It can contaminate surface water and groundwater, consequently drinking supplies, through agricultural activities such as cattle dairy farming or the spreading of manure fertilizer. The importance removing C. by filtration great interest because its long-term persistence oocysts resistance chemical disinfection owing thick cell wall. This relevant for both...

10.5194/egusphere-egu25-3798 preprint EN 2025-03-14

Transboundary rivers are crucial resources for drinking water, recreation, and irrigation. However, wastewater emissions global environmental demographic changes can impair raw water quality pose risks to public health. This study aims assess the impact of from treatment plants, combined sewer overflows (CSOs), inland waterway transport on microbiological safety along upper Danube River Basin (DRB).To achieve this, we developed a stochastic mathematical model trace pathogen load throughout...

10.5194/egusphere-egu25-8167 preprint EN 2025-03-14
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