- Genetics, Aging, and Longevity in Model Organisms
- Circadian rhythm and melatonin
- CRISPR and Genetic Engineering
- Vitamin D Research Studies
- Epigenetics and DNA Methylation
- Air Quality and Health Impacts
- Per- and polyfluoroalkyl substances research
- Medical Image Segmentation Techniques
- Photosynthetic Processes and Mechanisms
- Cancer Immunotherapy and Biomarkers
- Cerebrovascular and Carotid Artery Diseases
- Ferroptosis and cancer prognosis
- Neurobiology and Insect Physiology Research
- Medical Imaging Techniques and Applications
- Spaceflight effects on biology
Nanyang Technological University
2024
Shanxi Medical University
2024
Second Hospital of Shanxi Medical University
2024
West China Medical Center of Sichuan University
2022-2023
Olfactory integration is important for survival in a natural habitat. However, how the nervous system processes signals of two odorants present simultaneously to generate coherent behavioral response poorly understood. Here, we characterize circuit basis form olfactory Caenorhabditis elegans . We find that presence repulsive odorant, 2-nonanone, threat strongly blocks attraction other odorants, such as isoamyl alcohol (IAA) or benzaldehyde, signal food. Using forward genetic screen, found...
The auto-labeling of coronary artery segments plays an important role in the diagnosis cardiovascular diseases. Due to high degree complexity and diversity structures, it is still a very challenging task after many years exploration study. In this paper, we propose hierarchical scheme based on PointNet++ models new topological structural features for automatic labeling segments. inputs are 3D centerline points extracted from CTCA images, outputs correspondent label indexes. include two...
Numerous studies have demonstrated that immune cell infiltration is a significant predictor in the prognosis of those with breast cancer. This study aimed to develop prognostic model for undifferentiated cancer using immune-related markers. Differentially expressed genes (DEGs) and factors were identified from The Cancer Genome Atlas (TCGA) database. immune-associated filtered GeneCards Least absolute shrinkage selection operator (LASSO) Cox proportional hazards regression employed select...
Sodium azide (NaN 3 ) is widely used as an anesthetic in the C. elegans community for studying animal behavior. It not known whether other azides can function anesthetics. This quite important labs which NaN a convenient choice, such all located China, where under tight regulation, and alternative anesthetics need to be characterized. In present study, we focused on another three azides, potassium (KN ), trimethylsilyl (TMSA), diphenyl phosphoryl (DPPA), are regulated China. We characterized...
The miniMOS technique has been widely used in the C. elegans community to generate single copy insertions. A worm is considered as a potential insertion candidate if it resistant G418 antibiotics and does not express co-injected fluorescence marker. If expression of extrachromosomal array very low, possible for be mistakenly identified candidate, this low level can still confer resistance without producing detectable signal from co-injection This may increase workload identifying locus...