Mengxiang Zhao

ORCID: 0000-0002-9823-0917
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About
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Research Areas
  • Composting and Vermicomposting Techniques
  • Banking stability, regulation, efficiency
  • Immune Cell Function and Interaction
  • MicroRNA in disease regulation
  • RNA modifications and cancer
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Epigenetics and DNA Methylation
  • Cancer Immunotherapy and Biomarkers
  • Selenium in Biological Systems
  • Nematode management and characterization studies
  • Cancer-related gene regulation
  • Peptidase Inhibition and Analysis
  • Glioma Diagnosis and Treatment
  • Corporate Finance and Governance
  • Plant Reproductive Biology
  • Cancer, Hypoxia, and Metabolism
  • Constructed Wetlands for Wastewater Treatment
  • Proteoglycans and glycosaminoglycans research
  • Circular RNAs in diseases
  • Inflammasome and immune disorders
  • IL-33, ST2, and ILC Pathways
  • Antibiotic Resistance in Bacteria
  • Wastewater Treatment and Reuse
  • State Capitalism and Financial Governance
  • Hypothalamic control of reproductive hormones

Northwest A&F University
2022-2024

Southwestern University of Finance and Economics
2023

Nanjing University
2019-2022

Objectives: Integrins, the coordinator of extracellular and intracellular signaling, are often found to be aberrant in tumors can reshape tumor microenvironment. Although previous studies showed that integrin beta 2 (ITGB2) is important for host defense, its expression profile role tumors, especially cancer associated fibroblasts (CAFs) still unknown. Methods: Immunofluorescence stain fluorescence activated cell sorting were used analyze ITGB2 oral squamous carcinoma (OSCC). RT-PCR western...

10.7150/thno.47901 article EN cc-by Theranostics 2020-01-01

Abstract The Pattern Of Invasion (POI) of tumor cells into adjacent normal tissues clinically predicts postoperative metastasis/recurrence early oral squamous cell carcinoma (OSCC), but the mechanisms underlying development these subtypes remain unclear. Focusing on highest score POIs (Worst POI, WPOI) present within each tumor, we observe a disease progression-driven shift WPOI towards high-risk type 4/5, associated with mesenchymal phenotype in advanced OSCC. 4-5-derived cancer-associated...

10.1038/s41467-022-32787-y article EN cc-by Nature Communications 2022-08-31

MLL2 (mixed-lineage leukemia 2) is recognized as an essential role in regulating histone 3 lysine 4 tri-methylation (H3K4me3) mammalian cells. It frequently mutated to promote developmental diseases and tumor initiation. However, the expression pattern of its clinical significance for patients with early-stage oral squamous cell carcinoma (OSCC) remain totally unknown.Eighty-five samples primary OSCC were enrolled this retrospective study, immunohistochemistry (IHC) was performed detect...

10.1111/jop.12969 article EN Journal of Oral Pathology and Medicine 2019-10-29

Programmed cell death 4 (PDCD4) as a tumor suppressor gene inhibits growth and metastasis of cancer cells, which involved with eIF4A1, the inhibitor translation initiation. Although prognosis early-stage oral squamous carcinoma (OSCC) is generally better, but many patients occur recurrence after surgery. Understanding clinical expression pattern PDCD4/eIF4A1 signal would provide diagnostic biomarker target therapy premise for OSCC patients.Immunohistochemical analysis was performed on 69...

10.2147/cmar.s223273 article EN cc-by-nc Cancer Management and Research 2019-11-01

CD38 belongs to the ribosyl cyclase family and is expressed on various hematological cells involved in immunosuppression tumor promotion. Although targeting antibodies has been approved for treatment of multiple myeloma, function solid tumor, oral squamous cell carcinoma (OSCC) etc., not investigated.This retrospective study included 92 OSCC samples analyzed spatial distribution by immunohistochemistry (IHC). The values diagnosis prognosis were evaluated. Additionally, 53 preoperative...

10.3389/fonc.2021.687430 article EN cc-by Frontiers in Oncology 2021-06-15

10.1016/j.frl.2024.105817 article EN Finance research letters 2024-07-10

Reelin, an extracellular glycoprotein, is expressed on neuronal cells and participates in migration during brain development. Recently, Reelin also has a vital role carcinogenesis. However, its oral squamous cell carcinoma (OSCC) remains to be explored. The purpose of this study was explore the roles OSCC.The expression cancer-associated fibroblasts (ReelinCAF) tumor (ReelinTC) analyzed by Gene Expression Omnibus (GEO) database. Immunohistochemistry (IHC) used detect spatial pattern 75...

10.3389/fonc.2021.692390 article EN cc-by Frontiers in Oncology 2021-08-17

Both academics and industry experts are interested in identifying groups of funds most likely to outperform others the future. This study gathers data on actively managed mutual from 2007 2021 China construct portfolios superior using fund confidence set (FCS) algorithm proposed by Grønborg et al. (2021). Carhart’s four-factor model (Carhart, 1997) Lian’s (Lian al., 2021) adopted compared. generally outperforms model, indicating a better characterization Chinese market. Unlike Grønborg’s FCS...

10.2139/ssrn.4548131 preprint EN 2023-01-01
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