A5061408186- Environmental Toxicology and Ecotoxicology
- Marine Biology and Environmental Chemistry
- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- bioluminescence and chemiluminescence research
- Marine Toxins and Detection Methods
- Marine Biology and Ecology Research
- Neuropeptides and Animal Physiology
- Insect and Pesticide Research
- Advanced biosensing and bioanalysis techniques
- Receptor Mechanisms and Signaling
- Dental materials and restorations
- Orthopaedic implants and arthroplasty
- Pharmaceutical and Antibiotic Environmental Impacts
- Marine Ecology and Invasive Species
- Pesticide and Herbicide Environmental Studies
- Isotope Analysis in Ecology
- Environmental Chemistry and Analysis
- Microplastics and Plastic Pollution
- Peptidase Inhibition and Analysis
- Aquaculture Nutrition and Growth
- Parasite Biology and Host Interactions
- interferon and immune responses
- Toxic Organic Pollutants Impact
- Insect Pest Control Strategies
Japan Fisheries Research and Education Agency
2013-2024
Showa University
2000-2013
Ehime University
2009-2013
Hokkaido University
2013
Health Sciences University of Hokkaido
2005-2012
Nihon University
2012
Hiroshima University
2003-2006
Showa Pharmaceutical University
1992-2005
We evaluated the median lethal concentrations (LC50s) of pyrithione (PT) antifoulants copper (CuPT) and zinc (ZnPT) to a teleost, red sea bream (Pagrus major), crustacean, toy shrimp (Heptacarpusfutilirostris). The 96-h LC50 values CuPT ZnPT, on basis actual concentrations, were 9.3 98.2 R.g/L, respectively, for 2.5 120 microg/L, shrimp. Histological observations revealed that secondary lamellae gill filaments experimental fish heavily damaged after exposure PTs, suggesting fatal hypoxemia...
This paper develops a mathematical model for describing the within-plate variation as RSD (relative standard deviation) of absorbance measurements in wide concentration range competitive ELISA and proposes method determining limit detection (LOD) quantitation (ROQ). The 17 alpha-hydroxyprogesterone is taken an example. theoretical description involves analyte independent variable error sources parameters which concern pipetting measurement. Our can dispense with repeated experiments real...
In 1998, during a toxicological surveillance of various marine fouling organisms in Hiroshima Bay, Japan, specimens the ribbon worm, Cephalothrix simula (Nemertea: Palaeonemertea) were found. These worms contained toxins with extremely strong paralytic activity. The maximum toxicity terms tetrodotoxin (TTX) was 25,590 mouse units (MU) per gram for whole worm throughout monitoring period. main toxic component isolated and recrystallized from an acidified methanolic solution. crystalline...
The purpose of this study is to compare in vivo retention BMP-2 and bone induction HAp (porosity: 60–80%, pore size: 100–600 μm, sintering temperature: 800°C, surface area: 1 m2 /g) β-TCP 75%, 100–400 tem
Abstract The aim of this study is to estimate the increase bone‐inductive potency by human demineralized dentin matrix (DDM) with recombinant bone morphogenetic protein‐2 (BMP‐2). Human teeth were crushed, completely in 0.6 M HCl, and freeze‐dried. tooth‐derived material called DDM. shape DDM was a particle type its size varied from 0.4 0.8 mm. BMP‐2 dose‐dependent rat subcutaneous tissues demonstrated that volume induced marrow increased at manner. time‐course induction (5.0 μg)/DDM (70 mg)...
Capitella teleta Blake et al., 2009 is an opportunistic capitellid originally described from Massachusetts (USA), but also reported the Mediterranean, NW Atlantic, and North Pacific, including Japan. This putatively wide distribution had not been tested with DNA sequence data; intraspecific variation in morphological characters diagnostic for species assessed specimens non-type localities, status of Japanese population(s) was uncertain. We examined morphology mitochondrial COI (cytochrome c...
Dentin matrix is well known as the most insoluble collagen in human body. We already confirmed osteoinductive property by granules of demineralized dentin (DDM) histologically. Human DDM and root-dentin (DRD) mass were prepared from adult vital teeth. The hard tissue induction alone or DRD was estimated at 4 weeks after implantation. induced bone cartilage independently. In addition, bioassay recombinant BMP-2 (5.0 µg)/DDM µg)/DRD mouse subcutaneous intramuscular tissues, respectively....
Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide expressed in the central nervous system and peripheral organs. Previous studies revealed role distribution of PACAP rodent testis, however, its presence human testis testicular germ cell tumors not known. We used RT-PCR immunohistological observations to investigate whether tissue contain PACAP. The mRNAs for receptors were detected total RNA extracted from testes. immunoreactivity was observed spermatogonia spermatids...
We used a teleost fish, the mummichog (Fundulus heteroclitus), to conduct early life-stage toxicity testing for copper pyrithione (CuPT). Fertilized eggs were exposed CuPT at various concentrations 50 d under continuous flow-through conditions. Hatchability, survival, growth, and morphologic abnormalities measured. Hatchability did not differ significantly between any experimental group control groups. Survival growth reduced in groups 2 or 4 microg/L CuPT. During test, abnormalities, such...
We compared the anatomy of holotype palaeonemertean Cephalothrix simula (Iwata, 1952) with that holotypes hongkongiensis Sundberg, Gibson and Olsson, 2003 fasciculus 1952), as well additional specimens from Fukue (type locality C. simula) Hiroshima, Japan. While there was no major morphological discordance between these specimens, we found discrepancies actual morphology some statements in original description respect to supposedly species-specific characters. Our observation indicates three...
Purpose: Extensive research is actively ongoing for development of an ideal bone substitute that meets the gold standard. Tooth was selected as a donor site evaluation potentials in substitutes based on its similar chemical compositions to alveolar bone. Previous studies have evaluated inorganic components autogenous tooth graft material (AutoBT) and osteoconductivity. In continuation from previous studies, current study conducted analysis organic osteoinductivity AutoBT. Methods: Forty-six...