Chang Woo Lee

ORCID: 0000-0002-9905-680X
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About
Contact & Profiles
Research Areas
  • Semiconductor materials and devices
  • Metal and Thin Film Mechanics
  • 3D IC and TSV technologies
  • Electronic Packaging and Soldering Technologies
  • Diamond and Carbon-based Materials Research
  • Copper Interconnects and Reliability
  • Semiconductor Quantum Structures and Devices
  • Magnetic and transport properties of perovskites and related materials
  • Integrated Circuits and Semiconductor Failure Analysis
  • Advanced materials and composites
  • Advanced Surface Polishing Techniques
  • Additive Manufacturing and 3D Printing Technologies
  • Ferroelectric and Piezoelectric Materials
  • Organic Light-Emitting Diodes Research
  • Metallurgy and Material Forming
  • Semiconductor materials and interfaces
  • Advancements in Semiconductor Devices and Circuit Design
  • Advanced Sensor and Energy Harvesting Materials
  • Quantum Dots Synthesis And Properties
  • Thin-Film Transistor Technologies
  • Phase-change materials and chalcogenides
  • Chalcogenide Semiconductor Thin Films
  • Silicon Carbide Semiconductor Technologies
  • GaN-based semiconductor devices and materials
  • Transition Metal Oxide Nanomaterials

Yonsei University
2018-2023

University of Washington
2023

Korea Research Institute of Bioscience and Biotechnology
1999-2022

Kookmin University
2004-2020

Dong-A University
2014-2020

Korea Institute of Machinery and Materials
2012-2017

Kyung Hee University
2011-2015

Gyeongsang National University
2014

Kwangwoon University
2014

Korea Institute of Industrial Technology
2014

Leucyl-tRNA synthetase (LRS) is known to function as leucine sensor in the mammalian target of rapamycin complex 1 (mTORC1) pathway. However, pathophysiological significance its activity not well understood. Here, we demonstrate that for mTORC1 activation LRS can be decoupled from catalytic activity. We identified compounds inhibit leucine-dependent pathway by specifically inhibiting GTPase activating LRS, while affecting For further analysis, selected one compound, BC-LI-0186, which binds...

10.1038/s41467-017-00785-0 article EN cc-by Nature Communications 2017-09-25

Even low-intensity blue light emitted by display devices exerts hazardous effects on RPE cells, which might be solved if contain less short wavelength light.

10.1039/c7ib00032d article EN Integrative Biology 2017-01-01

In the defective SiC epitaxial layer, work function variation was observed by Kelvin probe force microscopy (KPFM), and difference came from of polytype disordered surface.

10.1039/c9nr10126h article EN Nanoscale 2020-01-01

Design procedures are presented for the snubber circuit in power electronic circuits by considering reverse recovery process of thyristor. The thyristor turnoff model, whose parameters determined best fitting to device characteristics given on data sheets, is applied analyze behavior with and without a saturable reactor during time device. Based exact expressions derived various quantities interest including maximum stress, dv/dt, energy loss device, total plus associated circuit. Utilizing...

10.1109/63.17965 article EN IEEE Transactions on Power Electronics 1988-10-01

To achieve a high capacitance density for embedded decoupling capacitor applications, the aerosol deposition (AD) process was applied as thin film process. BaTiO3 films were fabricated on Cu substrates by AD at room temperature, and thickness reduced to confirm limit of critical minimum dielectric properties. As result, that less than 1-μm thick showed unstable electric properties owing their leakage currents. Therefore, overcome this problem, causes currents investigated. In study, it...

10.1186/1556-276x-7-264 article EN cc-by Nanoscale Research Letters 2012-05-22

The p38 mitogen activated kinase (MAPK) signaling pathway plays an essential role in regulating many cellular processes, including inflammation, cell differentiation, and death. Here, we report that the hepatitis C virus (HCV) core inhibits Fas-mediated pathway. activation is suppressed core-expressing HepG2 lines, as well hepatocytes of transgenic mice. In addition, protein blocked apoptosis signal-regulating 1 (ASK1), a major upstream MAPKKK p38. Treatment specific inhibitor (SB203580) or...

10.1016/s1016-8478(23)15058-8 article EN cc-by-nc-sa Molecules and Cells 2002-06-01

When the partial pressure ratio of WF6:NH3:H2 is 2:1:50, (111) and (200) oriented tungsten nitride (W2N) thin films can be deposited by plasma enhanced chemical vapor deposition resistivity as-deposited 95–100 μm cm. In order to improve adhesion (W) films, this W2N glue layer interposed between W Si. The acoustic emission-load graphs obtained scratch test method show that strengths on layers are apparently improved from 1–2 9–11 N. more adhesive contact attributed introduction nitrogen...

10.1063/1.107880 article EN Applied Physics Letters 1992-08-03

In order to investigate the dielectric strength properties of BaTiO3 films with nano-scale grains uniform grain size and no voids, were fabricated a thickness 1 μm by an AD process, sintered at 800, 900, 1000 °C in air reducing atmosphere. The have superior due their high density without any voids. addition, based on investigation leakage current (intrinsic) properties, it was confirmed that sintering conditions atmosphere largely increase currents generated electrons doubly ionized oxygen...

10.1063/1.4851675 article EN Journal of Applied Physics 2014-01-06

The aim of this study was to investigate the anti-tumor activity KBH-A42, a novel synthetic histone deacetylase (HDAC) inhibitor. KBH-A42 shown significantly suppress proliferation all 14 human cancer cell lines tested. Among these lines, leukemia line K562 most sensitive, whereas UM-UC-3 bladder cells were least sensitive. Additionally, in tumor xenograft model using Balb/c nude mice, inhibit growth tumors, although it only slightly inhibited tumors. results flow cytometry analysis and...

10.3892/ol.2011.430 article EN Oncology Letters 2011-09-28

Robust massless Dirac states with helical spin textures were realized at the boundaries of topological insulators such as van der Waals (vdW) layered Bi2Se3 family compounds. Topological properties can be controlled by varying film thickness, external stimuli, or environmental factors. Here, we report single-crystal-quality growth ultrathin films on flexible polyimide sheets and manipulation vdW gap. X-ray diffraction unambiguously demonstrates that under uniaxial bending stress gap...

10.1021/acs.jpcc.8b06296 article EN The Journal of Physical Chemistry C 2018-09-28

Skin-based wearable devices have gained significant attention due to advancements in soft materials and thin-film technologies. Nevertheless, traditional electronics often entail expensive intricate manufacturing processes rely on metal-based substrates that are susceptible corrosion lack flexibility. In response these challenges, this paper has emerged with an alternative substrate for electrodes its cost-effectiveness scalability manufacturing. Paper-based offer attractive solution their...

10.3390/s23249727 article EN cc-by Sensors 2023-12-09
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