Background The accurate determination of low density lipoprotein cholesterol (LDL-c) is pertinent in clinical practice. Most laboratories employ the Friedewald formula, for convenient estimation LDL-c, despite its shortfalls. Different formulae have been proposed use, more but LDL-c. Here, we compare a new formula recently by de Cordova et al., with that and LDL-c determined homogeneous assay. We also assess performance at very TG levels against modified recommended Ahmadi al. Methods A...

Abstract Early notification of critical values by the clinical laboratory to treating physician is a requirement for accreditation and essential effective patient management. Many laboratories automatically repeat value before reporting it prevent possible misdiagnosis. Given today’s advanced instrumentation quality assurance practices, we questioned validity this approach. We performed an audit repeat-testing in our assess significant differences between initial repeated test results,...

The incidence of metabolic syndrome (MetS), is rapidly increasing in developing countries. However, the epidemiology MetS not well reported pediatric and young adult population. We determined prevalence its components among overweight obese Nigerian adolescents adults presenting for university admission.A cross-sectional study was performed. Blood pressure readings were taken while participants seated. Anthropometric measures waist circumference, weight height also using standard protocols...

Inadequately completed laboratory test request forms contribute to preanalytical errors and limit the advice of pathologists when interpreting results. Educating clinicians about this has been proposed by several studies as a strategy reduce occurrence.We aimed determine effectiveness such education on prevalence adequately forms.This was quasi-experimental study conducted at chemical pathology Lagos University Teaching Hospital, Nigeria. Incoming were audited for period 1 month looking out...

South Africa has the highest burden of tuberculosis (TB) in World Health Organization (WHO) African region. Using traditional TB diagnostic tools, diagnosis pleural (PTB) is highly unrewarding. Elevated levels fluid adenosine deaminase (FADA) have been shown to be useful PTB; however, similar may found some other medical conditions leading misdiagnosis. Following queries from clinicians concerning likely high false-positive (FP) rate FADA our laboratory, we performed a retrospective audit...

Insulin-induced type III hypersensitivity reactions (HSRs) are exceedingly rare and pose complex diagnostic management challenges. We describe a case of 43-year-old woman with 1 diabetes mellitus (DM), severe insulin resistance, subcutaneous nodules at injection sites, accompanied by elevated anti-insulin IgG autoantibodies. Treatment involved therapeutic plasma exchange (TPE) intravenous immunoglobulin (IVIg) as bridge therapy, followed long-term immunosuppression, which reduced...

Introduction The need for timely patient management has led to the proliferation of point-of-care testing (POCT) within health care facilities. However, POCT is often implemented without supervision by laboratory personnel, which raises concern about quality its results. aim this study was determine practices in several Nigerian tertiary hospitals. Materials and Method This a descriptive 61 sites at 5 hospitals across Nigeria. Research laboratories self-monitoring were excluded. Data...

Abstract Introduction/Objective Lipoid pneumonia is an uncommon inflammatory lung lesion resulting from the aspiration of endogenous or exogenous oily substances. It has no age sex preponderance, and its mode presentation non- specific. Radiologic imaging findings may mimic that a malignant lesion. Methods We report case 69-year-old female with history chronic obstructive pulmonary disease, rheumatoid arthritis 30-pack year smoking. She was being followed for enlarging PET positive...

Background: Critical value notification (CVN) entails notifying doctors or other laboratory users of aberrant results that threaten the patient’s life and any values for which reporting delays could negatively impact health. practices in clinical laboratories Nigeria sub-Saharan Africa are largely unknown.Objective: We conducted a nationwide survey to obtain baseline information on CVN practice by Nigeria’s laboratories.Methods: This cross-sectional study was among purposively selected...

Abstract Introduction/Objective Paragangliomas are tumors originating from the neural crest. Most benign and arise various locations in body. Extra-adrenal paragangliomas as sporadic cases most settings or part of heredofamilial syndromes about one-quarter cases. Succinate dehydrogenase subunit B (SDHB) gene mutations associated with an aggressive clinical disease course pheochromocytoma/paraganglioma. Methods We present a 41-year-old male former smoker history growing right upper lung...

Introduction: Paragangliomas are tumors originating from the neural crest. Most of them benign and arise various locations in body. Extra-adrenal paragangliomas as sporadic cases most settings or part heredofamilial syndromes about one-quarter cases. Succinate dehydrogenase subunit B (SDHB) gene mutations associated with an aggressive clinical disease course pheochromocytoma/paraganglioma.Methods: We present a 41-year-old male former smoker history growing right upper lung nodule on chest...

Introduction: Angiosarcoma of the gastrointestinal tract is a rare, aggressive malignant neoplasm vascular origin. Commonly, this tumor occurs due to metastases from other sites like head and neck region soft tissue. When occurring as primary intestines, entity poses diagnostic dilemma its non-specific clinical presentation, coupled infiltrative features that may occur without an obvious lesion amenable routine interventions. The findings autopsy surgical case with brief review relevant...