A5019165896- Acute Ischemic Stroke Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- HIV-related health complications and treatments
- Clinical Laboratory Practices and Quality Control
- Ethics in Clinical Research
- Gestational Diabetes Research and Management
- Diabetes Management and Research
- Cardiovascular Health and Disease Prevention
- Lipoproteins and Cardiovascular Health
- Stroke Rehabilitation and Recovery
- Pregnancy and preeclampsia studies
- Air Quality and Health Impacts
- Global Public Health Policies and Epidemiology
- Liver Disease Diagnosis and Treatment
- Venomous Animal Envenomation and Studies
- Venous Thromboembolism Diagnosis and Management
- Municipal Solid Waste Management
- Molecular Biology Techniques and Applications
- Ultrasound and Hyperthermia Applications
- Radiology practices and education
- Meta-analysis and systematic reviews
- Ophthalmology and Visual Health Research
- Mycotoxins in Agriculture and Food
- Lipid metabolism and disorders
- Healthcare and Environmental Waste Management
Jos University Teaching Hospital
2015-2025
University of Jos
2015-2025
Federal Medical Centre
2017
Tygerberg Hospital
2016
Stellenbosch University
2016
National Health Laboratory Service
2016
BackgroundSub-Saharan Africa has the highest incidence, prevalence, and fatality from stroke globally. Yet, only little information about context-specific risk factors for prioritising interventions to reduce burden in sub-Saharan is available. We aimed identify characterise effect of top modifiable Africa.MethodsThe Stroke Investigative Research Educational Network (SIREN) study a multicentre, case-control done at 15 sites Nigeria Ghana. Cases were adults (aged ≥18 years) with confirmed by...
Abstract Background: Chronic liver disease (CLD) in the clinical context is a process affecting liver, which involves of progressive destruction and regeneration parenchyma, leading to fibrosis cirrhosis. Both FibroScan, an ultrasound study also known as transient elastography, Hyaluran test (biochemical test) are rapid safe non-invasive examinations can be used monitor degree progression fibrotic changes liver. Objective: The purpose this was compare fibrosis, measured on ultrasound-based...
Introduction Stroke is a prominent cause of death, disability, and dementia in sub-Saharan Africa (SSA). The Investigative Research Education Network works collaboratively with stroke survivors individuals serving as community controls to comprehensively characterize the genomic, sociocultural, economic behavioral risk factors for SSA. Purpose In this paper, we aim to: i) explore attitudes, beliefs, practices related Ghana Nigeria using process qualitative description; ii) propose actions...
Africa was previously insufficiently represented in the emerging discipline of biobanking despite commendable early efforts. However, with Human, Heredity, and Health (H3Africa) initiative, biorepository science has been bolstered, regional biobanks are springing up, awareness about is growing on continent. The Stroke Investigative Research Educational Network (SIREN) project a transnational, multicenter, hospital community-based study involving over 3000 cases controls recruited from 16...
Abstract Background Frequent fruit and vegetable consumption is considered a promising dietary behaviour that protects health. However, most existing studies about the factors associated with this phenomenon among Africans are based on single-country reports, apart from one meta-regression combining smaller studies. This study harmonized large datasets assessed frequency of in population. Methods Individual-level data sociodemographics, lifestyle diet 20 443 participants across five African...
To identify the qualitative and quantitative contributions of conventional risk factors for occurrence ischemic stroke its key pathophysiologic subtypes among West Africans.The SIREN (Stroke Investigative Research Educational Network) is a multicenter, case-control study involving 15 sites in Ghana Nigeria. Cases include adults aged ≥18 years with who were etiologically subtyped using A-S-C-O-D classification into atherosclerosis, small-vessel occlusion, cardiac pathology, other causes,...
Timeliness of laboratory results is crucial to patient care and outcome. Monitoring turnaround times (TAT), especially for emergency tests, important measure the effectiveness efficiency services. Laboratory-based clinical audits reveal opportunities improving quality. Our aim was identify most critical steps causing a high TAT cerebrospinal fluid (CSF) chemistry analysis in our laboratory.A 6-month retrospective audit performed. The duration each operational phase across work flow examined....
Snake bite is a neglected public health issue in many tropical and subtropical countries of the world. About 5.4 million snakebites occur each year, resulting 1.8 to 2.7 cases envenomation yearly. Hepatic markers have been reported rise 3-6 hours after injection venom experimental animals. This study aims biochemically assess ALT, AST GGT levels as biomarkers Echis ocellatus victims snake presenting at JUTH Comprehensive Health Centre Zamko 6hours post-bite compare with values those bitten...
Background: Aflatoxin B1causes damage to the DNA by alkylation of bases and P53 mutation. Exposure this mycotoxin is associated with development liver cancer. Measures reduce grain cereal contamination have been a focus however, effects these measures are still lagging behind exposure continues occur even in populations at risk developing cancer.
 Objective: To quantify aflatoxin B1 population HIV infected patients without HCC.
 Method: This was cross-sectional study among 196 or...
Background: Low and medium income countries (LMICs) especially in sub-Saharan Africa face unique challenges screening diagnosing hyperglycaemia pregnancy. The implications of applying the 2013 WHO modifications for assessing pregnancy low resource settings are not known. We evaluated significance these recent changes classification among pregnant Nigerian women.Methods: reviewed records Oral glucose tolerance test conducted on 600 women at Jos University Teaching Hospital (JUTH) between July...
The global prevalence of type 2 diabetes is increasing. Dyslipidaemia a known complication mellitus manifesting frequently as cardiovascular diseases and stoke. Elevation small, dense low density lipoprotein has been recognised component the atherogenic phenotype associated with complications. We speculate that elevation this particle may be antecedent phenotype. This study therefore aims to determine pattern dyslipidaemia among patients in Jos, North-Central Nigeria. One hundred seventy-six...
HIV/AIDS is an increasingly important cause of cardiovascular (CVD) morbidity world-wide. We sought to evaluate the prevalence CVD risk factors in HIV positive (HIV+) adults and assessment these risks using Framingham score (FRS). A cross-sectional study adult clients clinic at Jos University Teaching Hospital. One hundred fifty HIV+ selected randomly with 50 (age sex matched) negative (HIV-) participants were enrolled. Relevant history, physical examination biochemical investigations...
human immunodeficiency virus (HIV) is evolving into a leading cause of cardiovascular diseases (CVD) in sub-Saharan Africa (SSA) where the burden HIV remains high. Atherosclerosis underlie progression to CVD. We therefore examined prevalence subclinical atherosclerosis and its association with traditional non-traditional risk factors for CVD Nigerian HIV-infected adults.this was cross-sectional study involving randomly selected stable patients undetectable viral load attending clinics at Jos...
Biomass use in small unit combustion systems such as for space heating or cooking could lead to ineffective mixing and potential problems arising from emissions of gaseous particulate pollutants. We therefore conducted a study measure pollution levels public kitchens using biomass fuel ascertain their air quality indices. Markers indoor CO, SO2, H2S, PM2.5 PM10 were measured eleven (11) selected secondary schools over period four months by set active sampling devices. It is revealed that the...
Background: Asbestos is identified as a hazardous substance of public health concern and has led to its regulation or ban in many countries. Local international politics have hampered the outright this While UK USA did not out rightly but regulated use, most developing countries continue production, sale use asbestos mostly due economic reasons. The objective review identify previous publications on highlighting effects bordering regulation. Also recommend measures curtail especially...
The prevalence and usefulness of MetS in determining CVD risk at-risk populations are influenced by its definition. In a cohort HIV-positive Nigerians, we evaluated based on various defining criteria, their agreement with one another, association to endpoint, Carotid-Intimal-Media-Thickness (CIMT).
Obesity is linked to non-communicable conditions. We looked at obesity using four definable criteria and their relationship biochemical inflammatory indicators of cardiovascular diseases (CVDs) in people living with HIV (PLHIV).
Background: Antenatal healthcare providers’ (AHPs) knowledge about hyperglycaemia in pregnancy (HIP) and its screening best practices affect the management of affected pregnant women. We assessed HIP associated factors amongst first line AHPs.
 Methods: This descriptive cross-sectional study involved 188 Doctors, Nurses Community Health providers directly providing antenatal care at all levels health Jos, Plateau State, Nigeria, selected through total sampling technique.
 Result: A...
Since actual metal emissions can be assessed using Particulate matter (PM) as a proxy, monitoring and controlling compounds in biomass is essential for determining their quantities potential health effects. Using low volume respirable dust sampler, indoor ambient metal-bearing particles were quantified in-situ collected from nine (9) randomly selected public kitchens of boarding secondary schools Jos, Plateau State. Atomic absorption spectrometry (AAS) was used to determine the amounts...
Introduction The need for timely patient management has led to the proliferation of point-of-care testing (POCT) within health care facilities. However, POCT is often implemented without supervision by laboratory personnel, which raises concern about quality its results. aim this study was determine practices in several Nigerian tertiary hospitals. Materials and Method This a descriptive 61 sites at 5 hospitals across Nigeria. Research laboratories self-monitoring were excluded. Data...
Background: To determine the challenges in diagnostic support for adequate fluid and electrolyte (F/E) management a poor-resource critical care setting.Methods: This cross-sectional survey was conducted between March May 2017 one hundred four (104) doctors practicing tertiary hospitals North-central Nigeria. These were currently working Accidents Emergency Units (A/E), Intensive (ICU) Children have worked at least two months prior to study. They given structured questionnaire fill return....