A5063988537- Acute Ischemic Stroke Management
- Global Public Health Policies and Epidemiology
- Stroke Rehabilitation and Recovery
- Smoking Behavior and Cessation
- Ethics in Clinical Research
- Microbial Natural Products and Biosynthesis
- Blood Pressure and Hypertension Studies
- Fungal Biology and Applications
- Diverse Scientific Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Health and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Obesity, Physical Activity, Diet
- Cerebrovascular and Carotid Artery Diseases
- Air Quality and Health Impacts
- Biomedical Ethics and Regulation
- Anesthesia and Sedative Agents
- Mobile Health and mHealth Applications
- Plant Pathogens and Fungal Diseases
- Essential Oils and Antimicrobial Activity
- HIV-related health complications and treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- COVID-19 and healthcare impacts
- Oral Health Pathology and Treatment
- Coronary Artery Anomalies
Kwame Nkrumah University of Science and Technology
2016-2025
O. P. Jindal Global University
2025
Kwame Nkrumah University
2015-2024
University of Ghana
2020-2024
University of New Brunswick
2023
Tampere University
2023
Banaras Hindu University
2015-2022
Sawai ManSingh Medical College and Hospital
2020-2022
Iowa State University
2021
Lovely Professional University
2021
BackgroundSub-Saharan Africa has the highest incidence, prevalence, and fatality from stroke globally. Yet, only little information about context-specific risk factors for prioritising interventions to reduce burden in sub-Saharan is available. We aimed identify characterise effect of top modifiable Africa.MethodsThe Stroke Investigative Research Educational Network (SIREN) study a multicentre, case-control done at 15 sites Nigeria Ghana. Cases were adults (aged ≥18 years) with confirmed by...
The potential of mobile-health (mHealth) technology for the management hypertension among stroke survivors in Africa remains unexplored. We assessed whether an mHealth technology-enabled, nurse-guided intervention initiated patients within one month symptom onset is effective improving their blood pressure (BP) control.A two-arm pilot cluster randomized controlled trial involving 60 survivors, ≥18 years, with BP ≥140/90 mmHg at screening/enrollment visit a medical center Ghana. Participants...
Stroke exacts an immense toll in sub-Saharan Africa where there are few resources, and stroke prevention research is limited. The aim of this study to test the feasibility preliminary efficacy m-Health technology-enabled, nurse-guided intervention improving blood pressure (BP) control among Ghanaian patients within 1 month symptom onset.We conducted a 2-arm cluster pilot randomized controlled trial involving 60 recent survivors encountered single tertiary medical system Ghana. Subjects arm...
As the second leading cause of death and adult-onset disability, stroke is a major public health concern particularly pertinent in Sub-Saharan Africa (SSA), where nearly 80% all global mortalities occur, burden projected to increase coming decades. However, traditional emerging risk factors for SSA have not been well characterized, thus limiting efforts at curbing its devastating toll. The Stroke Investigative Research Education Network (SIREN) project aimed comprehensively evaluating key...
Background: Screen time has become an inevitable aspect of daily life due to increased technological access and changes in the social economic landscapes. The increase screen is associated with development various health conditions. Contextually, research on its impact been studied widely. Therefore, present study tried understand trends themes global aspects. Method: We adopted a bibliometric review, data were extracted from SCOPUS database, limiting it 2012-2023 (n =4077). final number...
Hypertension is the premier modifiable risk factor for recurrent stroke. In sub-Saharan Africa (SSA) where stroke burden escalating, little known about role of behavioral interventions in enhancing blood pressure (BP) control after Our objective to test whether an m-Health technology-enabled, nurse-led, multilevel integrated approach effective improving BP among Ghanaian patients within 1 month symptom onset compared with standard care.This two-arm cluster randomized controlled feasibility...
<h3>Objective</h3> To characterize risk factors for spontaneous intracerebral hemorrhage (sICH) occurrence and severity among West Africans. <h3>Methods</h3> The Stroke Investigative Research Educational Network (SIREN) study is a multicenter case-control involving 15 sites in Ghana Nigeria. Patients were adults ≥18 years old with CT-confirmed sICH age-, sex-, ethnicity-matched stroke-free community controls. Standard instruments used to assess vascular, lifestyle, psychosocial factors....
The endophytic fungi are an important source of bioactive natural products. This study includes evaluation antimicrobial activity and phytochemical analysis fungus ACQR8, recovered from the root tissues a folk medicinal plant Cissus quadrangularis L., which was identified as Fusarium proliferatum by microscopic molecular methods. showed broad spectrum antibacterial antifungal activities against variety human pathogens. To best our knowledge, this is first to record any sp. phytopathogens...
Endophytic fungi are the plant symbiont with highly diverse nature and poorly defined ecological importance in host fitness. Although there reports on isolation characterization of fungal endophytes from a variety hosts, is still no report Penicillium citrinum Azadirachta indica. In this study, an endophytic P. was isolated A. The purified fraction secondary metabolites characterized by combining TLC, GC-MS, 1H NMR 13C analyses. TLC identified as milbemycin. pure did not show any antioxidant...
The authors have completed and submitted the ICMJE Form for disclosure of Potential Conflicts Interest none was reported.
Extracellular synthesis of silver and gold nanoparticles using aqueous cell-free filtrate (CFF) endophytic Chaetomium globosum characterization its bioactive proteins.Temperature pH gradients were used to assess their effects on dimensions NPs. NPs tested in vivo for antibacterial activity. MALDI-TOF-MS/MS was CFF proteins.Fungal fabricated various shape under varied physicochemical conditions. Silver showed significantly (p ≤ 0.5) enhanced activity against Staphylococcus aureus Klebsiella...
Introduction Stroke is a prominent cause of death, disability, and dementia in sub-Saharan Africa (SSA). The Investigative Research Education Network works collaboratively with stroke survivors individuals serving as community controls to comprehensively characterize the genomic, sociocultural, economic behavioral risk factors for SSA. Purpose In this paper, we aim to: i) explore attitudes, beliefs, practices related Ghana Nigeria using process qualitative description; ii) propose actions...
Data on the burden of hypertension among people living with HIV (PLWH) in Africa are limited, especially after new expert consensus guidelines were published 2017. The authors sought to assess prevalence and factors associated PLWH. This is a cross-sectional study involving PLWH combination antiretroviral therapy (cART) (n = 250) compared sex-matched cART-naïve 201) Ghana. Hypertension was defined as blood pressure ≥ 140/90 mm Hg or use antihypertensive drugs. also assessed predictors using...
Ample fruit and vegetable (F&V) intake has been associated with a decreased risk of chronic disease. The health-enhancing effects increased F&V consumption, however, would be even more apparent if the consumption additionally led to lower unhealthy, high calorie snacks. Therefore, present study aimed investigate whether primary school-based intervention (the Dutch Schoolgruiten Project) that promoted could reduce snacks during school breaks.The applied longitudinal design baseline two...
Stroke is the leading cause of neurological hospital admissions in sub-Saharan Africa (SSA) and second death globally. The Investigative Research Education Network seeks to comprehensively characterize genomic, sociocultural, economic, behavioral risk factors for stroke build effective teams research address decrease burden other noncommunicable diseases SSA. One first steps this goal effectively engage communities that suffer high disease. purpose article describe plans elucidate...