A5030977661- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Hepatocellular Carcinoma Treatment and Prognosis
- Viral-associated cancers and disorders
- Aortic Disease and Treatment Approaches
- Chronic Lymphocytic Leukemia Research
- Colorectal Cancer Screening and Detection
- Mycotoxins in Agriculture and Food
- RNA modifications and cancer
- Immunodeficiency and Autoimmune Disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Animal Disease Management and Epidemiology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Hip and Femur Fractures
- COVID-19 and healthcare impacts
- HIV-related health complications and treatments
- Cardiac Valve Diseases and Treatments
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- Pharmaceutical Practices and Patient Outcomes
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Antibiotic Use and Resistance
Jos University Teaching Hospital
2016-2024
University of Jos
2016-2024
University Teaching Hospital
2021
Hepatocellular carcinoma (HCC) is an increasing cause of mortality in Nigeria among persons with HIV (PLH), as access to antiretroviral therapy (ART) improves. In this study we describe clinical, radiological, and laboratory characteristics Nigerian adults HCC, without HIV, examine how impacts survival.This prospective observational was conducted between August 2018 November 2021 at two hospitals [Jos University Teaching Hospital (JUTH) Lagos (LUTH)]. Subjects ≥18 years HCC diagnosed...
Approximately 80 million people live with chronic hepatitis B virus (HBV) infection in the WHO Africa Region. The natural history of HBV this population is poorly characterised, and may differ from patterns observed elsewhere due to differences prevailing genotypes, environmental exposures, co-infections, host genetics. Existing research largely drawn small, single-centre cohorts, limited follow-up time. Hepatitis Collaborative Network (HEPSANET) was established 2022 harmonise process...
Hepatocellular carcinoma (HCC) is an increasing cause of mortality in HIV-infected individuals. We compared host and tumour characteristics between HIV-uninfected Nigerians with HCC examined the impact HIV on survival.This prospective observational study was conducted at Jos University Teaching Hospital Jos, Nigeria, among adults (>18 years) enrolled September 2015 2017 followed until April 2019. Demographics, survival were subjects without HIV.101 (10 91 HIV-uninfected) [male 72%; median...
Infectious disease treatment and prevention are threatened by antimicrobial resistance (AMR) globally. The knowledge attitudes of doctors regarding AMR the responsible use antibiotics critical to improving prescribing behaviours mitigating danger that poses. This study aims assess practices in Nigeria AMR.
Background: Aflatoxin B1causes damage to the DNA by alkylation of bases and P53 mutation. Exposure this mycotoxin is associated with development liver cancer. Measures reduce grain cereal contamination have been a focus however, effects these measures are still lagging behind exposure continues occur even in populations at risk developing cancer.
 Objective: To quantify aflatoxin B1 population HIV infected patients without HCC.
 Method: This was cross-sectional study among 196 or...
ABSTRACT Objective In sub-Saharan Africa, hepatitis B is the principal cause of liver disease. Non-invasive biomarkers fibrosis are needed to identify patients requiring antiviral treatment. We assessed aspartate aminotransferase-to-platelet ratio index (APRI), gamma-glutamyl transferase-to-platelet (GPR) and FIB-4 diagnose significant cirrhosis in an individual patient data (IPD) meta-analysis. Design total, 3,549 from 12 cohorts HBsAg positive individuals 8 African countries were included....
Obesity is linked to non-communicable conditions. We looked at obesity using four definable criteria and their relationship biochemical inflammatory indicators of cardiovascular diseases (CVDs) in people living with HIV (PLHIV).
Background: The burden of chronic viral hepatitis among people living with human immunodeficiency virus (PLWH) and its association liver disease in Nigeria has been seldom explored. Our objective was to compare characteristics PLWH without significant fibrosis/cirrhosis, examining other risk factors. Methods: Cross-sectional study fibrosis/cirrhosis (transient elastography ≥ 9.3 kPa) between July 2018 August 2022. Data were compared participant groups logistic regression used determine...
Previous studies in Nigeria have reported the presence of hepatitis B virus (HBV) genotype E and availability immune escape mutants. There is a paucity data on chronic patients long-term antiviral therapy for HBV infection.
Background and Aim: One of the key components O ne Health approach to epidemic preparedness is raising awareness increasing knowledge emerging infectious diseases, prevention, risk reduction. However, related research can involve significant risks biosafety biosecurity. For this purpose, we organized a multidisciplinary hands-on workshop inform increase diseases mitigation. This study aimed describe process outcome training program using pproach across multi-specialty group in Nigeria....
Abstract Purpose: In Nigeria, over 3 million people are infected with HIV (prevalence rates 6.1-8.0%). Rates of co-infection HBV and HCV among HIV-infected common ranging from 9-12.3% (HBV) 6-20% (HCV). Given the high burden HIV/HBV co-infection, it is hypothesized that there HCC individuals in Nigeria. This abstract describes pattern liver diseases detected by abdominal ultrasound, including abnormalities suggestive HCC, a screening program. Methods: this cross-sectional study, all...