A5030774408- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Gastrointestinal disorders and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastrointestinal motility and disorders
- Microscopic Colitis
- Inflammatory Bowel Disease
- Diverticular Disease and Complications
- Colorectal Cancer Screening and Detection
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Pancreatic and Hepatic Oncology Research
- Platelet Disorders and Treatments
- HIV/AIDS Research and Interventions
- Blood groups and transfusion
- Foreign Body Medical Cases
- Intestinal and Peritoneal Adhesions
- Genetic factors in colorectal cancer
- Hemostasis and retained surgical items
- Diagnosis and treatment of tuberculosis
University of Lagos
2016-2024
Lagos University Teaching Hospital
2016-2024
Federal Medical Centre
2020
Brookdale University Hospital and Medical Center
2020
Lancet Laboratories
2020
University of Calabar
2020
Lagos State University Teaching Hospital
2016
Lagos State Health Service Commission
2011
Hepatocellular carcinoma (HCC) is an increasing cause of mortality in Nigeria among persons with HIV (PLH), as access to antiretroviral therapy (ART) improves. In this study we describe clinical, radiological, and laboratory characteristics Nigerian adults HCC, without HIV, examine how impacts survival.This prospective observational was conducted between August 2018 November 2021 at two hospitals [Jos University Teaching Hospital (JUTH) Lagos (LUTH)]. Subjects ≥18 years HCC diagnosed...
Introduction Recurrent abdominal pain (RAP) is a common reason for referral to the paediatric gastroenterology unit and attending physician needs be able rule out an organic cause when evaluating any child with this condition. The aim of study was describe endoscopic findings in children who presented Lagos University Teaching Hospital (LUTH) RAP. Methods This prospective descriptive which conducted from January 2015 July 2018 at Paediatric Gastroenterology department Paediatrics endoscopy...
Dyspepsia is prevalent in the community. Guidelines recommend early endoscopy dyspeptic patients who are older than 55 years, or have alarm features. There a lack of data on with features Nigeria.A retrospective study endoscopic findings adults dyspepsia and features, between August 1st 2017 July 31st 2018 Lagos, Nigeria. Data were analysed using Statistical Package for Social Sciences, version 23.0. The sensitivity, specificity, positive predictive value, negative value calculated.One...
Background. Paediatric endoscopy is now standard care in the developed world for management of gastrointestinal (GI) disorders. However, developing countries remains an underutilised tool. Objective. To determine indications and spectrum endoscopic findings children seen at Lagos University Teaching Hospital, Nigeria. Methods. The upper GI ≤16 years old, referred procedure from June 2013 to 2016, were documented. yield these was also determined. Results. In total 71 during study period....
Background: There is need for the appropriate use of gastroscopy.
 Objective: To determine appropriateness upper gastrointestinal endoscopy, and its association with significant endoscopyfindings in our environment.
 Methods: This was a prospective study subjects who underwent gastroscopy at two centers south-western Nigeria betweenAugust 2020 August 2021. Indications were classified as either or inappropriate according to ASGE guidelines, gastroscopic findings not significant,...
Background: Hepatitis C virus is an important cause of chronic liver disease with 71 million people worldwide living HCV infection as at 2015. Nigeria has the second largest burden HIV in Africa, 3.2 Nigerians HIV/AIDS 2016. Most infected hepatitis are asymptomatic and often unaware their infection. This study was conducted to determine prevalence risk factors for infections among apparently healthy individuals Lagos.Materials methods: a retrospective which antibodies determined who...
Lower gastrointestinal bleeding (LGIB) (hematochezia) is an important indication for colonoscopy, and may be caused by hemorrhoids, diverticulosis, tumors.The aim of this study was to compare the endoscopic findings in young (<50 years) versus older subjects (≥50 with LGIB Nigeria.This a retrospective all adults from January 2017 December 2019 Lagos, Nigeria. The records two centers that deliver outpatient services were ploughed biodata, presenting complaints these individuals. These data...
Background: The upsurge in the reported cases of diverticular disease (DD) has led to a re-appraisal earlier held views that it was rare entity Nigeria. advent colonoscopy contributed no small way this change. We sought determine clinical characteristics, indications for colonoscopy, and intra-procedural findings among these patients. Materials Methods: A retrospective cross-sectional study carried out on records from four private endoscopy units based Lagos State, were drawn 5-year period...
To document the clinical presentation, endoscopic diagnosis, and Sheffield scores of children with gastrointestinal (GI) bleeding who were referred for endoscopy at Lagos University Teaching Hospital. The participants needed based on criteria according to also documented.This study analyzed records 111 GI retrospectively from January 2013 2021, while 9 recruited prospectively February 2021 March 2022. Receiver operating curves area under curve generated test ability predict rebleeds,...
Inflammatory bowel disease (IBD) is a chronic and life-long characterized by gastrointestinal tract inflammation caused the interplay of host’s genetic predisposition, immune responses, various environmental factors. It diarrhea, among other symptoms. Its spectrum comprises Crohn’s (CD), Ulcerative Colitis (UC), indeterminate colitis (IC). occurs in two peaks, first at 15-25 years, second 40-60 years. rarely reported extremes age. Here we report case 93-year-old woman with previously...
Abstract Background: The link between hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) has been well established. There is a dearth of scientific data on the important phenomenon familial clustering these diseases in sub-Saharan Africa. This study evaluated prevalence risk HBV first-degree relatives spouses patients with HCC. Materials Methods: case–control was conducted Nigerian hospital. A total 211 confirmed 110 HCC 212 matched controls were consecutively recruited....
Background: The burden of chronic viral hepatitis among people living with human immunodeficiency virus (PLWH) and its association liver disease in Nigeria has been seldom explored. Our objective was to compare characteristics PLWH without significant fibrosis/cirrhosis, examining other risk factors. Methods: Cross-sectional study fibrosis/cirrhosis (transient elastography ≥ 9.3 kPa) between July 2018 August 2022. Data were compared participant groups logistic regression used determine...
Inflammatory bowel disease (IBD), though well described in the Caucasian population, is rarely encountered black African children. The aim of this study was to increase awareness emerging condition children and highlight constraints management a resource-limited setting like Nigeria.This included an audit with IBD who were seen between January 2015 February 2020 at Lagos University Teaching Hospital (LUTH). clinical records aged one 16 years presented recurrent abdominal pain, weight loss,...
Introduction: Colonoscopy is the standard investigation for assessing colonic disease, with moderate yield. The American Society Gastrointestinal Endoscopy (ASGE) published guidelines to tailor appropriate use of colonoscopy. aims this study were determine frequency at which colonoscopy was performed an indication based on ASGE´s 2012 guidelines, and if there association appropriateness endoscopic findings.
The term “microscopic colitis” (MC) is used to describe a chronic inflammatory bowel disease that includes two main subtypes based on histopathologic features: collagenous and lymphocytic. Scientific literature replete with documentation of the from various regions world. However, condition rarely described in black African patients. We herein present details clinical aspects endoscopic findings 3 Nigerian patients lymphocytic variant MC. A short review clinical, endoscopic, pathologic...
A 68-year-old woman presented with a three-week history of upper abdominal discomfort, vomiting coffee ground substance, and passage tarry stools. There were no typical risk factors for gastroduodenal or liver disease. Gastroscopy done showed fishbone impacted in the wall pyloric opening its free end abutting on duodenum resulting duodenal ulcer. Antral erosions also noted. Retrieval forceps used to retrieve fishbone. The patient did not remember eating any fish containing meal, there was...
Background: Upper gastrointestinal bleeding (UGIB) is a common indication for endoscopy. We aimed to describe the endoscopic findings in patients referred our center with UGIB. Methods: This was singlecenter retrospective study of UGIB between August 1, 2017, and April 30, 2019, Lagos, Nigeria. Data were analyzed using Statistical Package Social Sciences version 23.0.Results: Eight hundred thirty-two underwent endoscopy, which 129 (16%) UGIB, occurred twice as frequently males. Melena most...
Abstract Background and Objectives: Recent guidelines from international gastroenterology bodies recommend that upper gastrointestinal endoscopy (UGIE) should not be routinely performed in patients with dyspepsia who are younger than 60 years old as the yield for major abnormalities is low. The objectives of this study were to determine spectrum UGIE findings document association alarm features them. Materials Methods: This a retrospective records adult at five centers Lagos, Nigeria,...
Abstract Purpose: In Nigeria, over 3 million people are infected with HIV (prevalence rates 6.1-8.0%). Rates of co-infection HBV and HCV among HIV-infected common ranging from 9-12.3% (HBV) 6-20% (HCV). Given the high burden HIV/HBV co-infection, it is hypothesized that there HCC individuals in Nigeria. This abstract describes pattern liver diseases detected by abdominal ultrasound, including abnormalities suggestive HCC, a screening program. Methods: this cross-sectional study, all...