Florencia Pollarsky
A5086080438- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Alcohol Consumption and Health Effects
- Drug-Induced Hepatotoxicity and Protection
- Cardiovascular Disease and Adiposity
- Folate and B Vitamins Research
- Liver Diseases and Immunity
- Hepatitis C virus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cystic Fibrosis Research Advances
- Nutrition and Health in Aging
- Organ Transplantation Techniques and Outcomes
- Genetic Syndromes and Imprinting
Western University
2024
University of Louisville
2024
London Health Sciences Centre
2024
University of Buenos Aires
2020-2023
•AH hepatitis is associated with multi-organ failure and high short-term mortality.•MELD 3.0 predicted 30- 90-day mortality better compared the MELD-Na score mDF.•MELD was not superior to MELD ABIC scores in predicting mortality, but its classification accuracy similar between countries.•MELD best predictor of renal replacement therapy requirements other models. Background & AimsModel for End-Stage Liver Disease (MELD) predicts alcohol-associated (AH) could underestimate severity women...
Background and Aims: Alcohol-associated hepatitis (AH) poses significant short-term mortality. Existing prognostic models lack precision for 90-day Utilizing artificial intelligence in a global cohort, we sought to derive validate an enhanced model. Approach Results: The Global AlcHep initiative, retrospective study across 23 centers 12 countries, enrolled patients with AH per National Institute Alcohol Abuse Alcoholism criteria. Centers were partitioned into derivation (11 centers, 860...
We aimed to evaluate the effect of acute-on-chronic liver failure (ACLF) on patients' 1-year post-liver transplant (LT) survival. In addition, we evaluated ACLF development post-LT chronic kidney disease (CKD) and early allograft dysfunction (EAD).A retrospective cohort patients who underwent transplantation from 2010 2016 was studied. EASL-CLIF's definition used. The risk death, CKD, EAD estimated with regression models weighted by inverse probability weighting considering recipients'...
Alcohol-associated hepatitis (AH) corresponds to a severe entity with high short-term mortality; however, few studies have been published in patients moderate AH. This study aimed characterize AH global study, identifying prognostic factors and survival at 30, 90, 180 days. Multi-center retrospective cohort which included (2009-2019). Moderate was defined as MELD 20 presentation. We used competing-risk models liver transplantation competing risk assess variables associated mortality. 564 (24...
Alcohol-associated hepatitis (AH) is a severe entity with mortality of up to 30–50% at 1 month. Pentoxifylline combined steroids has not demonstrated benefits in AH. Some studies have suggested that pentoxifylline may be beneficial the subgroup patients acute kidney injury (AKI) and However, there no solid evidence its benefit this setting. This study aimed determine use AH AKI. Global retrospective cohort study, including AKI admission (2009–2019). We used competing-risk models liver...
Alcohol-associated hepatitis (AH) is a severe entity associated with high mortality. Corticosteroids might be used in cases disease and several dynamic models can predict mortality response to corticosteroids AH patients. However, there no consensus on the best of them. This study aimed evaluate corticosteroid treatment based short-term patients worldwide cohort. A retrospective cohort (between 2009 – 2019). We included who received calculated Lille model day 4 (Lille-4), 7 (Lille-7)...
Fibrosis staging in patients with nonalcoholic fatty liver disease (NAFLD) is carried out through the application of stepwise algorithms but there little real-world data on their use. Our aim was to calculate number NAFLD and indeterminate or high risk for fibrosis, assessed noninvasive scores, that consequently underwent further evaluation. A cross-sectional multicenter cohort study conducted evaluated by hepatologists within time frame June 1 July 31, 2018. The FIB-4 fibrosis scores were...
Fibrosis staging in patients with nonalcoholic fatty liver disease (NAFLD) is carried out through the application of stepwise algorithms but there little real-world data on their use. Our aim was to calculate number NAFLD and indeterminate or high risk for fibrosis, assessed noninvasive scores, that consequently underwent further evaluation.
Although most cases of HCC occur in patients with advanced liver disease and there are effective screening methods, health policies aimed at preventing detecting not often on the agenda government initiatives policies. This study to explore HCC-related population-wide public policies, treatment availability, epidemiological surveillance, awareness campaigns Americas. We conducted a 43-item survey about among experts from 12 countries. Questions were classified into four categories: civil...