María Laura Garrido
- Liver Disease Diagnosis and Treatment
- Alcohol Consumption and Health Effects
- Liver Disease and Transplantation
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis C virus research
- Liver Diseases and Immunity
- SARS-CoV-2 and COVID-19 Research
- Urinary Tract Infections Management
- Drug-Induced Hepatotoxicity and Protection
- Veterinary medicine and infectious diseases
- Hepatitis B Virus Studies
- Brucella: diagnosis, epidemiology, treatment
Mayo Clinic in Arizona
2024
University of Louisville
2024
Centro Científico Tecnológico - San Luis
2021-2024
Universidad de Sevilla
1983
•AH hepatitis is associated with multi-organ failure and high short-term mortality.•MELD 3.0 predicted 30- 90-day mortality better compared the MELD-Na score mDF.•MELD was not superior to MELD ABIC scores in predicting mortality, but its classification accuracy similar between countries.•MELD best predictor of renal replacement therapy requirements other models. Background & AimsModel for End-Stage Liver Disease (MELD) predicts alcohol-associated (AH) could underestimate severity women...
Background and Aims: Alcohol-associated hepatitis (AH) poses significant short-term mortality. Existing prognostic models lack precision for 90-day Utilizing artificial intelligence in a global cohort, we sought to derive validate an enhanced model. Approach Results: The Global AlcHep initiative, retrospective study across 23 centers 12 countries, enrolled patients with AH per National Institute Alcohol Abuse Alcoholism criteria. Centers were partitioned into derivation (11 centers, 860...
Alcohol-associated hepatitis (AH) corresponds to a severe entity with high short-term mortality; however, few studies have been published in patients moderate AH. This study aimed characterize AH global study, identifying prognostic factors and survival at 30, 90, 180 days. Multi-center retrospective cohort which included (2009-2019). Moderate was defined as MELD 20 presentation. We used competing-risk models liver transplantation competing risk assess variables associated mortality. 564 (24...
Alcohol-associated hepatitis (AH) is a severe entity with mortality of up to 30–50% at 1 month. Pentoxifylline combined steroids has not demonstrated benefits in AH. Some studies have suggested that pentoxifylline may be beneficial the subgroup patients acute kidney injury (AKI) and However, there no solid evidence its benefit this setting. This study aimed determine use AH AKI. Global retrospective cohort study, including AKI admission (2009–2019). We used competing-risk models liver...
Autoimmune liver diseases (AILD), including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and sclerosing (PSC), are chronic immune-mediated conditions. This study aimed to assess the reality of AILD in Latin America (LA). A web-based survey consisting 35 questions on was distributed hepatologists affiliated with ALEH through social media. total 65 participated survey. The most treated region AIH. Widely available antibodies for diagnosis included anti-mitochondrial (100%),...
Alcohol-associated hepatitis (AH) is a severe entity associated with high mortality. Corticosteroids might be used in cases disease and several dynamic models can predict mortality response to corticosteroids AH patients. However, there no consensus on the best of them. This study aimed evaluate corticosteroid treatment based short-term patients worldwide cohort. A retrospective cohort (between 2009 – 2019). We included who received calculated Lille model day 4 (Lille-4), 7 (Lille-7)...
We analyze the case of a 49-year-old male patient who presented with clinical signs acute hepatitis an initial suspicion autoimmune etiology. Laboratory findings demonstrated positive antinuclear antibody, anti-smooth muscle antibody and high serum gamma globulin. Histology liver biopsy revealed changes compatible hepatitis, which associated International Autoimmune Hepatitis Group score 7, determined initiation treatment Meprednisolone Azathioprine. During follow-up, we received serological...