- Drug Solubulity and Delivery Systems
- Analytical Chemistry and Chromatography
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Photocatalysis Techniques
- Analytical Methods in Pharmaceuticals
- Polyoxometalates: Synthesis and Applications
- Carbon and Quantum Dots Applications
- Crystallization and Solubility Studies
- Protein purification and stability
- Advanced Nanomaterials in Catalysis
- Magnetism in coordination complexes
- Neuroinflammation and Neurodegeneration Mechanisms
- Water Quality Monitoring and Analysis
- Biological Activity of Diterpenoids and Biflavonoids
- X-ray Diffraction in Crystallography
- Inflammasome and immune disorders
- Phytochemistry and Biological Activities
- Lanthanide and Transition Metal Complexes
- Acute Kidney Injury Research
- Surface Modification and Superhydrophobicity
- Japanese History and Culture
- Nanocluster Synthesis and Applications
- Mobile and Web Applications
- Bioactive Natural Diterpenoids Research
- Bioactive natural compounds
Xinjiang Institute of Engineering
2017-2024
Xinjiang Technical Institute of Physics & Chemistry
2023
Xinjiang Academy of Forestry
2023
Xinjiang University
2023
Changsha Medical University
2023
Bristol-Myers Squibb (United States)
2003-2022
Chinese Academy of Sciences
2020-2021
Zhengzhou University of Light Industry
2019-2021
Nanjing University of Chinese Medicine
2021
Guangxi University of Science and Technology
2021
Lubrication plays a key role in successful manufacturing of pharmaceutical solid dosage forms; lubricants are essential ingredients robust formulations to achieve this. Although many failures operations caused by issues related lubrication, general, do not gain adequate attention the development formulations. In this paper, fundamental background on lubrication is introduced, which relationships between and friction/adhesion forces discussed. Then, application products processes discussed...
Kidney tubular epithelial cells are high energy-consuming that depend mainly on fatty acid oxidation for an energy supply. AMP-activated protein kinase (AMPK) is a key regulator of production in most cells, but the function AMPK acute kidney disease unclear. Here, we found rapid decrease Thr172-AMPKα phosphorylation after ischemia/reperfusion both vivo and vitro models. Mice with cell–specific AMPKα deletion exhibited exacerbated impairment apoptosis ischemia/reperfusion. deficiency was...
Numerous researches supported that oxidative stress and inflammation play important roles in the development of diabetic encephalopathy (DEP). Notoginsenoside R1 (NGR1), one major component Panax notoginseng, is believed to have anti-oxidative, anti-inflammatory neuroprotective properties. However, its effects against DEP underlying mechanisms are still unknown. In this study, db/db mice as well high-glucose (HG)-treated HT22 hippocampal neurons were used vivo vitro models estimate NGR1...
Abstract Pd nanoparticles (NPs) supported on Ti‐doped graphitic carbon nitride (g‐C 3 N 4 ) were synthesized by a deposition–precipitation route and subsequent reduction with NaBH . The features of the NPs studied XRD, TEM, FTIR, XPS, EXAFS 2 ‐physisorption measurements. It was found that had an average size 2.9 nm presented high dispersion surface g‐C Compared to loaded pristine , exhibited catalytic activity in formic acid dehydrogenation water at room temperature. enhanced could be...
Selective and visual detection of nitrite is realized through the inner-filter effect triggered by nitrite–thiol reaction based on green carbon dots.
Gly m Bd 28K, 30K and 60K are the major soybean (Glycine max (L.) Merr.) allergens limiting consumption of a good protein source for sensitive individuals. However, little is known about their temporal-spatial expression during seed development upon germination. The present data shows that soy accumulated in both embryonic axes cotyledon, but patterns differed depending on specific allergen. Allergens sooner to greater level cotyledons than axes. 28 began at 14 d after flowering, 7 earlier...
Drug-excipient compatibility studies lay the foundation for designing a chemically stable formulation clinical and commercial development. This article describes investigation of oxidative degradation encountered with compound A (a phenylalanine-drug complex) in capsule dosage form. Two wet- granulation formulations (2.5-mg 25-mg strengths) were developed using excipients that showed satisfactory stability from initial drug-excipient studies. Both strengths at 50 degrees C (closed) least 18...
CuO<sub>x</sub>/ERGO nanohybrids with diverse morphologies prepared by pH-regulated synthesis display tunable electrocatalytic ability towards nitrite sensing.
Compounds that target tumor epigenetic events are likely to constitute a prominent strategy for anticancer treatment. Histone deacetylase inhibitors (HDACis) have been developed as prospective candidates in drug development, and currently, many of them under clinical investigation. We assessed the efficacy now hydroxamate-based HDACi, YF-343, triple-negative breast cancer development studied its potential mechanisms.YF-343 was estimated novel HDACi by screening kit. The biological effects...
Spodoptera litura (tobacco caterpillar, S. litura) is a pest of great economic importance due to being polyphagous and world-distributed agricultural pest. However, practices involving chemical pesticides have caused resistance, resurgence, residue problems, highlighting the need for new, environmentally friendly methods control spread litura.This study aimed investigate gut poisoning grayanotoxin I, an active compound found in Pieris japonica, on litura, explore underlying mechanisms these...
AbstractThe reaction between manganese nitrate and N,Nʹ-(±)-ethylene-bis(salicylicyclohexanediaminate) ((±)-salcy) in dilute lacunary polyoxoanion [PW9O34]9− solution led to isolation of a new Mn-dimer, [Mn((±)-salcy)(N3)]2 (1). Structural analysis indicates that 1 represents the first salcy-based Mn-dimer complex. Magnetic susceptibility studies reveal shows single-molecule magnet (SMM) behavior from 2 5 K.Keywords: Schiff baseManganesePOM solutionMagnetic properties Additional...