A5101399253- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Gastric Cancer Management and Outcomes
- Infectious Diseases and Tuberculosis
- Gastrointestinal Tumor Research and Treatment
- Pneumonia and Respiratory Infections
- Pancreatic and Hepatic Oncology Research
- Diagnosis and treatment of tuberculosis
- Genetic factors in colorectal cancer
- Breastfeeding Practices and Influences
- Chemical Safety and Risk Management
- Antibiotics Pharmacokinetics and Efficacy
- Alcohol Consumption and Health Effects
- Nutrition and Health in Aging
- RNA and protein synthesis mechanisms
- Colorectal Cancer Treatments and Studies
- Liver Disease Diagnosis and Treatment
- Hemoglobinopathies and Related Disorders
- Metastasis and carcinoma case studies
- Enhanced Recovery After Surgery
- Esophageal Cancer Research and Treatment
- Respiratory and Cough-Related Research
- Fatty Acid Research and Health
- Clinical Nutrition and Gastroenterology
- Neonatal Health and Biochemistry
Gates Foundation
2024
Sichuan Cancer Hospital
2014-2024
First People’s Hospital of Jingmen
2023
Beijing Shijitan Hospital
2016-2021
Capital Medical University
2016-2021
Shandong Provincial Hospital
2020
Shandong First Medical University
2020
Nanjing University of Chinese Medicine
2019
Beijing Center for Disease Prevention and Control
2010-2018
Chinese Center For Disease Control and Prevention
2016-2017
AIM:To compare the short-term outcomes of patients who underwent proximal gastrectomy with jejunal interposition (PGJI) those undergoing total Roux-en-Y anastomosis (TGRY). METHODS:From January 2009 to 2011, thirty-five PGJI, and forty-one TGRY.The surgical efficacy follow-up were compared between two groups.RESULTS: There no differences in demographic clinicopathological characteristics.The mean operation duration postoperative hospital stay PGJI group statistically longer than TGRY (P =...
The present study was aimed to evaluate whether IgG, IgM and IgA antibodies levels detected against a novel Mycobacterium tuberculosis polyprotein 38 F-64 F (with being the abbreviation for 38kD-ESAT6-CFP10 64 Mtb8.4-MPT64-TB16.3-Mtb8) are suitable diagnosing active tuberculosis, monitoring efficacy of chemotherapy on TB patients. In this study, total 371 patients without treatment were selected categorized into S+/C+ group (n = 143), S-/C+ 106) or S-/C- 122). A series serum samples...
Detection of circulating Mycobacterium tuberculosis (M. tuberculosis) antigens is promising in Tuberculosis (TB) diagnosis. However, not a single antigen marker has been found to be widely expressed all TB patients. This study aimed prepare broadly reactive polyclonal antibodies targeting multiple markers (multi-target antibodies) and evaluate their efficacies diagnosis.A fusion gene consisting 38kD, ESAT6, CFP10 was constructed overexpressed. The polyprotein used as an immunogen elicit...
Background The purpose of this study was to evaluate the performance BACTEC MGIT 960 (M960) system compared with proportion method (PM) on Löwenstein-Jensen (L-J) medium in a peripheral laboratory China for testing Mycobacterium tuberculosis (MTB) susceptibility streptomycin (SM), isoniazid (INH) rifampicin (RIF) and ethambutol (EMB) combination known as SIRE. Methods 205 clinical isolates MTB SM, INH, RIF EMB performed M960 system. drugs were tested at following concentrations: 1.0 µg/ml...
Abstract Irritable bowel syndrome (IBS) is a common disorder of unknown etiology. Studies have found close relation between IBS and microRNAs (miRNAs), but the study concerning relationship miR‐181c‐5p in still blank. Thus, this aims to explore role via interleukin 1α (IL1A). Initially, microarray analysis was used retrieve genes related predict miRNAs regulating IL1A gene. model then established with abdominal withdraw reflection (AWR) Bristol stool grading mice measured. Afterwards,...
We examined colon cancer patients who received soluble dietary fiber enteral nutrition (SDFEN) to evaluate the feasibility and potential benefit of early SDFEN compared EN. Sixty were confirmed as having with histologically accepted radical resection randomized into an group EN group. The postoperative complications, length hospital stay (LOH), days for first fecal passage, difference in nutritional status, immune function inflammatory reaction between pre-operation post-operation all...
Abstract Background Tuberculosis is one of the most infectious diseases in world. Molecular typing methods such as spoligotyping, and VNTR (variable number tandem repeats), IS 6110 NTF region LSP (large sequence polymorphisms) analysis are generally useful tools for resolution various issues related to classical epidemiology Mycobacterium tuberculosis ( M. ). Methods To determine transmission characteristics strains isolated Beijing, China, their genetic relationships, especially those among...
Objective A retrospective study comparing the diagnostic performance of BACTEC™ MGIT™ 960 system (M960 system; BD Worldwide, Franklin Lakes, NJ, USA) with Löwenstein–Jensen (L–J) culture to detect mycobacteria in sputum specimens from patients suspected pulmonary tuberculosis (TB). Methods Sputum samples were analysed for presence acid-fast bacilli (AFB). Samples inoculated into M960 and L–J culture. Positive cultures examined AFB. Results The method detected significantly more positive than...
Rapid and accurate diagnosis of pulmonary tuberculosis (PTB) is an unresolved problem worldwide, especially for sputum smear− (S−) cases. In this study, five antigen genes including Rv3871, Rv3874, Rv3875, Rv3876, Rv3879 were cloned from Mycobacterium ( Mtb ) RD1 overexpressed to generate fragments. These antigens their combinations investigated PTB serodiagnosis. 298 serum samples collected active patients, 117 smear+ (S+) culture+ (C+) cases, 101 S−/C+ 80 S−/C− The IgG levels the measured...
Objective To compare the diagnostic performance of manual BACTEC™ Mycobacteria Growth Indicator Tube (MGIT™) system (M-MGIT) with automated MGIT™ 960 (A-MGIT) and Löwenstein-Jensen (L-J) culture method in detecting mycobacteria sputum specimens from patients suspected pulmonary tuberculosis (TB). Methods For this cross-sectional study, samples were taken aged ≥18 years attending a TB clinic Beijing, China between July 2015 October 2016. Processed inoculated into MGIT systems L-J medium for...
729 Background: This study conducted a large-scale multi-center analysis using real-world data from China to comprehensively investigate the clinical characteristics and prognosis of patients with deficient mismatch repair (dMMR) or high microsatellite instability (MSI-H) gastric colorectal cancer undergoing curative surgery. Additionally, we analyzed postoperative adjuvant treatment effects recurrence/metastasis patterns. Methods: We retrospectively 1800 dMMR and/or MSI-H confirmed by...
Objective To investigate the latest situation in period 2006-2008 of drug resistance tuberculosis among migratory population Chaoyang district Beijing.Methods All sputum culture-positive specimens from were collected.Drug susceptibility Mycobacterium to M,H,R and E tested by proportion method.Results Drug 371 isolates tested.Total wag 22.4%(83/371),the primary acquired 17.5%(58/331)and 62.5%(25/40)respectively.The multi-drug was 5.9%(22/371);the 4.2%(14/331)and 20.0%(8/40).The higher treated...