- Dental Health and Care Utilization
- Dental Implant Techniques and Outcomes
- Oral microbiology and periodontitis research
- Dental materials and restorations
- Geriatric Care and Nursing Homes
- Dental Education, Practice, Research
- Connective tissue disorders research
- Temporomandibular Joint Disorders
- Dental Erosion and Treatment
- Hepatitis C virus research
- interferon and immune responses
- Obstructive Sleep Apnea Research
- Systemic Lupus Erythematosus Research
- Economic and Environmental Valuation
- dental development and anomalies
- Renal function and acid-base balance
- Cleft Lip and Palate Research
- Liver Disease Diagnosis and Treatment
- Aging and Gerontology Research
- Asthma and respiratory diseases
- Cytokine Signaling Pathways and Interactions
- Nutritional Studies and Diet
- Patient Satisfaction in Healthcare
- Pediatric health and respiratory diseases
- CNS Lymphoma Diagnosis and Treatment
National University of Singapore
2018-2025
National Dental Centre of Singapore
2024
Niigata University
2017-2018
Osaka University
2010-2017
Osaka Dental University
2014-2016
Cork University Hospital
2014
Keio University
1996-2007
Kure Kyosai Hospital
1957
To summarize and discuss how geriatric dentistry has been addressed in dental schools of different countries regarding to (1) teaching students at the predoctoral level; (2) advanced training, (3) research.A convenience sample faculty members from a selection high, upper-middle lower-middle income were recruited complete survey. The survey had 5 open-ended main topics, asked about size their elderly population, general information education; number dentistry, methods; (4) training dentistry;...
Introduction: In long-term care settings (LTCs), oral health often remains fragmented from other geriatric services. Medical practitioners (MPs) typically take the lead in addressing medical aspects of plans, making it essential for them to understand importance and collaborate with dental professionals. However, little is known about MPs’ perceptions toward management LTCs. This qualitative study aimed gain an in-depth understanding views on LTCs explore challenges collaborating...
Crown-root ratio (CRR) is commonly recorded when planning prosthodontic procedures. However, there a lack of longitudinal clinical data evaluating the association between CRR and tooth survival. The aim this practice-based study was to assess impact on survival abutment teeth for removable partial dentures (RPDs). Data were collected from 147 patients provided with RPDs at dental hospital in Japan. In total, 236 clasp-retained 856 analyzed. Survival assessed using Kaplan-Meier methods Cox’s...
Abstract Aim Removable partial dentures ( RPD s) may have a negative impact on oral health and the potential to cause further tooth loss, especially of abutment teeth. However, no evidence indicates effective interval regular periodontal maintenance after provision. This practice‐based cohort study aimed examine visits survival Materials Methods One hundred ninety‐two patients had been previously provided with 304 new clasp‐retained s at Osaka University Dental Hospital, Japan. Using...
There has been a growing interest in the association between number of teeth and dietary intake older populations. However, people around age 80 y have frequently lost most their teeth, dental prostheses replacing missing play an important role masticatory function. Therefore, function cannot be evaluated by alone. The occlusal force complete arches is index function, reflecting not only but effect removable dentures. purpose this cross-sectional study was to determine relative importance...
Objectives To address the following research questions: (i) What is current situation and future vision on oral healthcare service in nursing homes (NHs) Singapore? (ii) are enablers to achieve vision? (iii) How do views differ between dentists with without clinical experiences NHs? Background Oral services NHs need reflect perspectives of a diverse range stakeholders establish shared goals, however there scarce evidence in‐depth dentists’ insights. Material methods Dentists were purposively...
Whereas most of studies investigating relationship between oral health and atherosclerosis have focused on periodontitis, very few them were examined about occlusal status natural teeth which possibly influence dietary habit. The primary aim this cross-sectional study was to investigate the association support posterior prevalence in community-dwelling septuagenarians. Also, second test hypothesis that intake key nutrients for prevention would a mediating effect atherosclerosis. population...
Abstract While aging simulation suits have been used in healthcare education to promote empathy for older adults, little has published on learning outcomes specific geriatric dental patients. We designed a seminar utilising customised ageing suit help students empathise with several disabilties their adult patients may face.
Oral healthcare service is not well integrated with existing policy in nursing homes (NHs) globally. This qualitative study aimed to identify dentists' perspectives on structural and system barriers that hinder oral (OHC) provision seniors NHs Singapore understand the consequences of these barriers.
The effect of IFN-alpha on the growth 5 hepatoma cell lines and a normal liver-derived line were examined. IFN dose-dependently inhibited except for HLE PLC/PRF/5 in which inhibition only occurred at high concentration over 10,000 IU/ml. induced G1 arrest these cells according to upregulation p21WAF-1 expression, is concentration. receptor was well expressed all lines. DNA rearrangement IRF-1 detected by Southern blotting, while IRF-2 gene preserved. IFN-induced expressions compared between...
Seventy-one cases of bronchial asthma were classified into three types: bronchospasm, bronchospasm-hypersecretion and bronchiolar obstruction types. The characteristics each type studied in relation to patient age at onset the disease. In 71 subjects studied, most frequent was bronchospasm followed by type. Intractable frequently observed least Most patients under 50 years showed characteristically accompanied blood eosinophilia when years. type, incidence intractable high age, but not...
Abstract Background Oral healthcare service provision for dependent older adults is often poor. For dental services to provide more responsive and equitable care, evidence-based approaches are needed. To facilitate future research, the development application of a core outcome set would be beneficial. The aim this study develop oral health research involving adults. Methods A multi-step process consensus methods including key stakeholders will undertaken. This involve identifying potentially...
There is no “gold-standard” material for the operative management of root caries. The aim this study was to determine if clinical performance Biodentine would be acceptable restoration caries in older adults. A randomized controlled trial conducted comparing a calcium silicate cement (Biodentine), high-viscosity glass ionomer (Fuji IX GP Extra), and resin-modified II LC). Of 334 volunteers assessed eligibility, 249 were excluded. total 303 lesions 85 participants randomized, with 151...
We recently reported promoter polymorphisms in the IRF-1 gene, an interferon-inducible gene that plays important role host antiviral function. The activity was shown to be different between polymorphisms. In this study, we investigated relationship and response interferon monotherapy for chronic hepatitis C. Eighteen patients with a low initial viral load or C virus (HCV) genotype non-1b received 6-months course of interferon-beta monotherapy. mutations treatment were investigated. type...
Abstract Background Hepatitis C virus (HCV) easily undergoes genomic changes, especially in the hypervariable region (HVR) N‐terminus of E2/NS1 region. The quasispecies nature HCV may have important biological implications relation to viral persistence; however, relationship between disease activity chronic infection and development complexity yielded conflicting results. We explored changes HVR‐1 natural course with without elevation serum alanine transaminase (ALT) levels. Materials...