A5102915608- Frailty in Older Adults
- Cardiac Health and Mental Health
- Nutrition and Health in Aging
- Magnetism in coordination complexes
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Lanthanide and Transition Metal Complexes
- Electron Spin Resonance Studies
- Hip and Femur Fractures
- Stroke Rehabilitation and Recovery
- Dental Implant Techniques and Outcomes
- Dental Health and Care Utilization
- Advanced Glycation End Products research
- Estrogen and related hormone effects
- Lung Cancer Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Cancer and Skin Lesions
- Heart Failure Treatment and Management
- Advanced Radiotherapy Techniques
- Neurological Disorders and Treatments
- Lung Cancer Treatments and Mutations
- Salivary Gland Disorders and Functions
- Dental Trauma and Treatments
- Rabies epidemiology and control
- Diabetes Management and Research
Nagoya City University
2025
Juntendo University
2018-2025
Osaka Rosai Hospital
2024
Osaka University
2002-2022
Juntendo University Shizuoka Hospital
2018
University of Electro-Communications
2010-2012
Japanese Red Cross Nagoya Daini Hospital
2002
Red Cross Hospital
2002
Osaka City University
2000
Heterometallic coordination compounds [Cu(II)(L)(C(3)H(6)O)Ln(III)(NO(3))(3)] and [V(IV)O(L)(C(3)H(6)O)Ln(III)(NO(3))(3)] (abbreviated as LnCu LnV, respectively; H(2)L = N,N'-bis(3-methoxysalicylidene)-1,3-diamino-2,2-dimethylpropane; Ln Gd, Tb, Dy, Ho, Er) were synthesized, the X-ray crystallographic analysis shows that their structures are isomorphous for each series. The single-molecule magnet behavior was observed TbCu DyCu, activation energies of magnetization reversal 42.3(4) 11.5(10)...
The advanced glycation end products (AGEs), which can be assessed through skin autofluorescence (SAF), have been linked to chronic kidney disease (CKD), diabetes mellitus (DM), and aging. However, it is unknown how frailty SAF levels are associated with cardiovascular (CVD). We enrolled 1,000 consecutive CVD patients who participated in phase II cardiac rehabilitation (CR) underwent assessment of between November 2015 September 2017 at Juntendo University Hospital. Of these, 48 were excluded...
Abstract Background and Aims Durvalumab plus tremelimumab (Dur/Tre) therapy is expected to have good therapeutic efficacy for patients with unresectable hepatocellular carcinoma (u‐HCC). We previously reported that the neutrophil‐to‐lymphocyte ratio (NLR) during atezolizumab bevacizumab in u‐HCC was a useful marker predicting response. Therefore, we investigated whether NLR Dur/Tre could predict treatment outcomes u‐HCC. Design The present study included 64 treated evaluated their initial...
The 4f-3d exchange couplings were definitively and precisely determined in the dinuclear complexes (Ln-M) involving double μ-oxo-bridges, by means of combined high-frequency electron paramagnetic resonance pulsed-field magnetization techniques, revealing a monotonic decrease ferromagnetic J(Ln-Cu) order atomic number, (64)Gd to (68)Er.
Abstract Background Advanced glycation end-products, indicated by skin autofluorescence (SAF) levels, could be prognostic predictors of all-cause and cardiovascular mortality in patients with diabetes mellitus (DM) renal disease. However, the clinical usefulness SAF levels heart failure (HF) who underwent cardiac rehabilitation (CR) remains unclear. This study aimed to investigate associations between MACE risk HF CR. Methods enrolled 204 consecutive had undergone CR at our university...
The Kihon Checklist is a useful screening tool for assessing frailty in older individuals. However, the clinical significance of cardiac rehabilitation patients remains unclear. present study aimed to evaluate relationship between and parameters who participated rehabilitation.We enrolled 845 consecutive (584 men, mean age 71 years) at Juntendo University Hospital, Tokyo, Japan, November 2015 October 2017. were divided into non-frailty (n = 287), pre-frailty 270) 288) groups according their...
Abstract Background Advanced glycation end products (AGEs) are associated with aging, diabetes mellitus (DM), and other chronic diseases. Recently, the accumulation of AGEs can be evaluated by skin autofluorescence (SAF). However, relationship between SAF levels exercise capacity in patients cardiovascular disease (CVD) remains unclear. This study aimed to investigate association tissue clinical characteristics, including capacity, CVD. Methods We enrolled 319 consecutive CVD aged ≥40 years...
Background/Aim: Radiotherapy-induced malfunction of pacemakers and cardiac defibrillators has been reported, corresponding guidelines have developed in various countries. Although several studies reported the effects radiotherapy patients with implantable left ventricular assist device (LVAD), its safety remains unclear. Herein, we report three cases stereotactic ablative (SABR) using CyberKnife for early-stage lung cancer LVAD. Case Report: Three their 50s or 60s, including two women one...
Cardiac rehabilitation (CR) is categorized as a class I recommendation in the guidelines for management of patients with cardiovascular disease (CVD). However, penetration rate outpatient CR low Japan. We designed pilot study to evaluate safety and feasibility tele-CR using remote biological signal monitoring system.
The frailty state consists of not only physical but also psycho-emotional problems, such as cognitive dysfunction and depression well social problems. However, few reports have examined the relationship between anxiety levels in elderly patients undergoing cardiac rehabilitation (CR).We analyzed 255 (mean age: 74.9 ± 5.8 years, 67% male) who participated early phase II CR at Juntendo University Hospital. At beginning CR, carried out self-assessments based on Kihon Checklist (KCL) State Trait...
Arterial stiffness contributes to the development of cardiovascular disease (CVD). However, relationship between arterial and exercise tolerance in CVD patients with preserved ejection fraction (pEF) those reduced EF (rEF) is unclear. We enrolled 358 who participated cardiac rehabilitation underwent cardiopulmonary testing at Juntendo University Hospital. After excluding 195 had undergone open heart surgery 20 mid-range EF, were divided into pEF (n = 99) rEF 44) groups. was assessed using...
Summary Although the shortened dental arch ( SDA ) concept has been known to all over world, acceptance of as an oral health standard can be questionable from patients' point view, even if it is biologically reasonable. Furthermore, because insurance system covers removable partial dentures RPD s) for citizens in Japan, patients seem prefer receive prosthetic treatment replace missing teeth. However, there were few field surveys investigate usage rate s Japan. The purpose this study was...
Peak oxygen uptake (peak VO2 ) and heart rate reserve (HRR) are independent prognostic markers of cardiovascular disease. However, the impact peak HRR on long-term prognosis after off-pump coronary artery bypass grafting (OP-CABG) remains unclear.To determine in patients OP-CABG.We enrolled 327 (mean age, 65.1 ± 9.3 years; male, 80%) who underwent OP-CABG participated early phase II cardiac rehabilitation. All participants cardiopulmonary exercise testing (CPET) at beginning such Overall, 48...
The Japanese Ministry of Health, Labour and Welfare reported that the overall constipation complaint rates among men women are 2.5% 4.6%, respectively. To evaluate impact on patients with cardiovascular diseases, we investigated association between frailty components in undergoing cardiac rehabilitation (CR).We enrolled 102 consecutive late phase II CR (mean age: 62.7 ± 13.4 years; 68 (67%) were men). We clinical characteristics, observed defecation status evaluated assessed by Kihon...
Pneumoperitoneum (PP), or air within the abdominal cavity, is frequently a harbinger of serious pathology and often represents visceral perforation. We herein report case combined massive intraperitoneal free air, pneumothorax pneumomediastinum but emergency laparotomy was negative. A sixty-seven-year-old man found unconscious on road after being hit by car. On arrival, he showed swelling head flail chest. Computed tomography (CT) demonstrated cerebral contusion, multiple bilateral rib...
We evaluated the effectiveness and safety of stereotactic ablative radiotherapy (SABR) delivered using Cyberknife in patients with stage I non-small-cell lung cancer.The clinical results 153 161 cancers treated CyberKnife between May 2014 August 2020 at Osaka University Hospital were retrospectively analyzed. The median age was 80 years (range=48-99 years). Nine (5.6%) had interstitial pneumonia. radiation dose 52 Gy (range=40-70 Gy) 4-10 fractions, follow-up extended to 21.4 months...
The patient was a 60-year-old male fell whose head and left chest hit the ground after falling from height of 2 m. He complained shoulder pain regaining consciousness. On arrival, he showed bloody otorrhea, tenderness, limited range motion due to pain. Emergency roentgenography revealed multiple rib fractures, clavicular fracture with decreased radiolucency in lung field, suggesting contusion. When being transported for computed tomography, suddenly displayed ventricular tachycardia pulse...
Cardiac rehabilitation refers to a long-term, multifaceted, comprehensive program designed optimize patient's physical, psychological, social, and vocational status. Early mobilization in intensive care units have become an established position the Japanese medical insurance system since "early addition (5,000 yen/patient/day, 14-day upper limit)" was newly revision of treatment fees FY2018.