A5029848975- Plant Molecular Biology Research
- Plant Reproductive Biology
- Tree Root and Stability Studies
- Leaf Properties and Growth Measurement
- Polysaccharides and Plant Cell Walls
- Plant nutrient uptake and metabolism
- Cellular Mechanics and Interactions
- Microtubule and mitosis dynamics
- Greenhouse Technology and Climate Control
- Remote Sensing in Agriculture
- Plant Gene Expression Analysis
- Cell Image Analysis Techniques
- Genetics and Plant Breeding
- Crop Yield and Soil Fertility
- DNA and Biological Computing
- Modular Robots and Swarm Intelligence
- Bioenergy crop production and management
- Hippo pathway signaling and YAP/TAZ
- Plant Pathogens and Fungal Diseases
- Neurobiology and Insect Physiology Research
- Advanced Fluorescence Microscopy Techniques
- Genetic Mapping and Diversity in Plants and Animals
- Visual perception and processing mechanisms
- Biocrusts and Microbial Ecology
- Plant Parasitism and Resistance
University of Bern
2012-2020
University of East Anglia
2009-2013
Max Planck Institute for Plant Breeding Research
2013
University of Calgary
2013
Norwich Research Park
2012-2013
John Innes Centre
2013
Morphogenesis emerges from complex multiscale interactions between genetic and mechanical processes. To understand these processes, the evolution of cell shape, proliferation gene expression must be quantified. This quantification is usually performed either in full 3D, which computationally expensive technically challenging, or on 2D planar projections, introduces geometrical artifacts highly curved organs. Here we present MorphoGraphX (www.MorphoGraphX.org), a software that bridges this...
Shape-Shifting Signals Although orthogonal signaling systems seem to direct various developmental processes, few tissues remain in the same shape as they are at initiation that of final form. Arabidopsis leaves free cell migrations complicate animal development, and thus allowed Kuchen et al. (p. 1092 ) track model trajectory leaf growth under a variety perturbations. Varying values parameters their produced outputs different shapes ranging from obcordate, ovate, oval elliptic, offered...
Significance During plant growth and development, the gene expression that promotes does not always spatially correlate with observed growth. This suggests additional factors guide morphogenesis. Here we propose mechanical cues play an instructive role test our hypothesis by using a full 3D cellular-level finite-element simulation model of mature Arabidopsis embryo. We demonstrate size, shape, arrangement cells all influence their ability to grow in response growth-promoting expression....
The mechanisms that generate dynamic spatial patterns within proliferating tissues are poorly understood, largely because of difficulties in unravelling interactions between cell specification, polarity, asymmetric division, rearrangements, and growth. We address this problem for stomatal spacing plants, which offer the simplifying advantage cells do not rearrange. By tracking lineages gene activities over extended periods, we show limited stem behavior precursors depends on maintenance...
The regulation of organ size constitutes a major unsolved question in developmental biology. wing imaginal disc Drosophila serves as widely used model system to study this question. Several mechanisms have been proposed an impact on final size, but they are either contradicted by experimental data or cannot explain number key observations and may thus be missing crucial elements. We modeled regulatory network that integrates the experimentally confirmed molecular interactions underlying...
Tissue cell polarity plays a major role in plant and animal development. We propose that fundamental building block for tissue is the process of intracellular partitioning, which can establish individual absence asymmetric cues. Coordination polarities may then arise through cell-cell coupling, operate directly, membrane-spanning complexes, or indirectly, diffusible molecules. Polarity anchored to tissues organisers located at boundaries. show how this partitioning-based framework be applied...
How complex developmental-genetic networks are translated into organs with specific 3D shapes remains an open question. This question is particularly challenging because the elaboration of in essence a mechanics. In plants, this means how genetic circuitry affects cell wall. The mechanical properties wall and their spatial variation key factors controlling morphogenesis plants. However, these difficult to measure investigating relation regulation challenging. To properties, one must...
Polar auxin transport lies at the core of many self-organizing phenomena sustaining continuous plant organogenesis. In angiosperms, shoot apical meristem is a potentially unique system in which two main modes auxin-driven patterning—convergence and canalization—co-occur coordinated manner fully three-dimensional geometry. epidermal layer, convergence points form, from canalized towards inner tissue. Each these patterning processes has been extensively investigated separately, but integration...
TTef [Eragrostis tef (Zucc.) Trotter] is an important crop in the Horn of Africa, particularly Ethiopia, where it a staple food for over 60 million people. However, productivity remains extremely low part due to its susceptibility lodging. Lodging displacement plant from upright position, and exacerbated by rain, wind application fertilizer. In order address issue global security, especially greater insight into causes lodging needed. this study, we combine modelling biomechanical...
The regulation of organ size constitutes a major unsolved question in developmental biology.The wing imaginal disc Drosophila serves as widely used model system to study this question.Several mechanisms have been proposed an impact on final size, but they are either contradicted by experimental data or cannot explain number key observations and may thus be missing crucial elements.We modeled regulatory network that integrates the experimentally confirmed molecular interactions underlying...
Abstract How complex developmental-genetic networks are translated into organs with specific 3D shapes remains an open question. This question is particularly challenging because the elaboration of in essence a mechanics. In plants, this means how genetic circuitry affects cell wall. The mechanical properties wall and their spatial variation key factors controlling morphogenesis plants. However, these difficult to measure investigating relation regulation challenging. To properties, one must...
Abstract Polar auxin transport lies at the core of many self-organizing phenomena sustaining continuous plant organogenesis. In angiosperms, shoot apical meristem is a potentially unique system in which two main modes auxin-driven patterning— convergence and canalization—co-occur coordinated manner fully three-dimensional geometry. epidermal layer, points form, from canalized towards inner tissue. Each these patterning processes has been extensively investigated separately, but integration...