A5100649363- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Corneal Surgery and Treatments
- Renal Transplantation Outcomes and Treatments
- Urinary Bladder and Prostate Research
- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Foot and Ankle Surgery
- Cancer, Lipids, and Metabolism
- Urinary and Genital Oncology Studies
- Pediatric Urology and Nephrology Studies
- Urologic and reproductive health conditions
- Renal and Vascular Pathologies
- Tendon Structure and Treatment
- Organ Transplantation Techniques and Outcomes
- Urological Disorders and Treatments
- Nutrition and Health in Aging
- Pelvic floor disorders treatments
- Renal and related cancers
- Cancer Genomics and Diagnostics
- Kidney Stones and Urolithiasis Treatments
- Gastric Cancer Management and Outcomes
- Organ Donation and Transplantation
Yonsei University
2016-2025
Severance Hospital
2018-2025
Pusan National University
2001-2024
Pusan National University Hospital
2022-2024
Government of the Republic of Korea
2018-2024
Ulsan College
2011-2023
University of Ulsan
2011-2023
Ulsan University Hospital
2012-2023
Korea Advanced Institute of Science and Technology
2023
Boramae Medical Center
2021
The aim of this study was to determine whether implantable collamer lens (ICL) implantation correct myopia is an effective and safe surgical option even after long-term follow up.A retrospective observational carried out.A total 281 eyes 145 myopic patients were included in the study.Patients underwent ICL had follow-up period at least 5 years (87 ± 18.9 months).Outcome measures uncorrected corrected distance visual acuities, refraction for evaluation efficacy, safety, stability...
We compared early continence recovery after surgical treatment of prostate cancer with Retzius sparing robot-assisted radical prostatectomy and conventional prostatectomy.Robot-assisted was done by a single surgeon in 1,863 cases between October 2005 May 2018 using the technique 1,150 713, respectively. To compare outcomes groups propensity score matching performed 9 preoperative variables, including age, body mass index, specific antigen, biopsy Gleason Grade Group, clinical T stage, volume...
AIM:To evaluate the natural history of subepithelial lesions. METHODS:We reviewed medical records 104 159 patients who underwent upper gastrointestinal endoscopy at Center for Health Promotion Samsung Medical between 1996 and 2003.Subepithelial lesions were detected in 795 (0.76%); 252 followed using 82.5 ± 29.2 mo (range, 12-160 mo; median, 84 1st quartile, 60 3rd 105 mo).The median interval follow-up was 12 6-105 24 mo). RESULTS:The mean patient age 53 years 22-80 years), male-to-female...
<b><i>Background/Aims: </i></b>Drug-induced acute kidney injury (AKI) has been a severe threat to hospitalized patients, raising the urgent needs develop strategies reduce AKI. We investigated protective activity of <i>Dendropanax morbifera</i> (DP), medicinal plant which widely used treat infectious and pain diseases, on using cisplatin-induced nephropathic models. <b><i>Methods: </i></b>Both <i>in vitro</i> renal...
The relationship between body fat distribution and survival remains unclear in patients with castration resistant prostate cancer treated docetaxel androgen receptor axis targeted agents. We investigated whether composition parameters could predict radiographic progression-free specific cancer.In this multicenter retrospective study we evaluated data on 282 consecutive diagnosed September 2009 March 2017. subcutaneous index, the visceral index skeletal muscle at diagnosis of were determined...
To investigate the differences in corneal endothelial cell morphology between diabetic patients who were divided by degree of severity retinopathy and normal after phacoemulsification with intraocular lens (IOL) implantation.Department Ophthalmology, College Medicine, Pusan National University, Pusan, Korea.Before 6 months phacoemulsification, specular microscopy was used to evaluate number cells retinopathy. The into 3 groups: group I (n=30 eyes), without diabetes; II diabetes severe...
Helicobacter pylori is a major risk factor for atrophic gastritis (AG) and gastric cancer. The correlation between H. pylori, AG colorectal neoplasm (CRN) has only been examined in limited number of studies, findings have inconclusive. We aimed to investigate the association infection status, advanced CRN.This cross-sectional study investigated relationship presence serum anti-H. IgG antibodies, AG, CRN 6,351 consecutive asymptomatic subjects who underwent screening colonoscopy.A total 316...
Robot-assisted radical prostatectomy (RARP) is performed by urologists as one of the surgical procedures for treating prostate cancer. Numerous studies have been published with regard to impact weight on performing RARP but were limited insufficient number patients and use transperitoneal approach. This study aimed determine effect gland short-term oncological outcomes using extraperitoneal In total, 1168 who underwent (EP-RARP) a single surgeon at Yonsei University Severance Hospital...
Abstract Background Healthy diets have been associated with better cognitive function. Socioeconomic factors including education, poverty, and job complexity may modify the relationship between diet cognition. Methods We used adjusted linear mixed models to examine association long-term adherence Mediterranean-Dietary Approaches Stop Hypertension - Intervention for Neurodegenerative Delay (MIND) function over 8 years of follow-up in Puerto Rican adults residing Boston, MA area (aged 45–75 at...
BRCA1, a tumor suppressor gene, is implicated in the repression and activation of transcription via interactions with diverse range proteins. The mechanisms regulating action BRCA1 are not fully understood. Here, we use promoters Gadd45α, p27 KIP1 p21 WAF1/CIP1 to demonstrate that SUMO1 represses transactivation potential by causing be released from augmenting histone deacetylation recruitment deacetylase (HDAC) activity. Consistently, silencing led release HDAC1 at target promoters,...
The Korean Society of Nephrology (KSN) launched the official End-Stage Renal Disease (ESRD) Patient Registry in 1985 and Internet online registry program was opened 2001. ESRD Committee KSN has collected data on dialysis therapy Korea through website. increasing number elderly people diabetic patients resulted a very rapid increase patients. total 58,860 (hemodialysis [HD], 39,509; peritoneal [PD], 7309; functioning kidney transplant [KT], 12,042). prevalence 1144.4 per million population...
Postoperative acute kidney injury (AKI) is still a concern in partial nephrectomy (PN), even with the development of minimally invasive technique. We aimed to compare AKI incidence between patients and without diabetes mellitus (DM) determine predictive factors for postoperative AKI. This case-matched retrospective study included 884 preoperative creatinine levels ≤1.4 mg/dL who underwent laparoscopic or robot-assisted PN December 2005 May 2018. Propensity score matching was employed match...
The role of cytoreductive nephrectomy (CN) in the treatment metastatic renal cell carcinoma (mRCC) remains unclear immuno-oncology (IO) era. results two randomized trials, CARMENA and SURTIME, questioned timing CN. However, despite latest advances systemic mRCC, previous trials have only used targeted therapy, no studies fully investigated CN immune checkpoint inhibitor (CPI) settings, there is an urgent need for future to better define
Prostate cancer (PCa) is characterized by complex genomic rearrangements such as the ETS oncogene family fusions, yet clinical relevance not well established. While paneled genetic tests of DNA repair genes are recommended in advanced PCa, conventional or cytogenetic tools ideal for genome-wide screening structural variations (SVs) balanced translocation due to cost and/or resolution issues.In this study, we tested feasibility whole-genome optical mapping (OGM), a newly developed platform SV...
Complaints from spinal cord injury (SCI) patients are typically related to physical disability affecting activities of daily life. However, difficulties with voiding and defecation and/or sexual function can also be major concerns. The general population even physicians generally unaware these complaints; therefore, this study focuses on surveying SCI regarding challenges that faced in life.A questionnaire was administered randomly anonymously who visited the Korea Spinal Cord Injury...
Background: Recently, as total ankle arthroplasty (TAA) has been widely performed, its outcomes and complications have reported. Heterotopic ossification (HO) after TAA reported in the posterior compartment of ankle. We report on a series HOs that developed anterior at talar neck region TAA. Methods: was performed using Hintegra Mobility 54 ankles (Hintegra, 21 ankles; Mobility, 33 ankles) from 2004 to 2012. The outcome assessed by visual analog scale (VAS), American Orthopaedic Foot &...