A5022481842- Healthcare and Venom Research
- Traditional Chinese Medicine Studies
- Health and Wellbeing Research
- Ginseng Biological Effects and Applications
- Gastric Cancer Management and Outcomes
- Nutrition and Health in Aging
- Diverse Approaches in Healthcare and Education Studies
- Health Systems, Economic Evaluations, Quality of Life
- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Mosquito-borne diseases and control
- Complex Systems and Time Series Analysis
- Folate and B Vitamins Research
- Chemical Synthesis and Reactions
- Synthesis and Catalytic Reactions
- Healthcare Education and Workforce Issues
- Ginkgo biloba and Cashew Applications
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Viral Infections and Vectors
- Cancer Genomics and Diagnostics
- Rheumatoid Arthritis Research and Therapies
- Viral Infectious Diseases and Gene Expression in Insects
- Computational and Text Analysis Methods
National Cancer Institute
2019-2025
Center for Cancer Research
2025
Dankook University
2013-2024
STR Biotech (South Korea)
2024
Konkuk University
2016-2024
Chosun University
2024
ABL Bio (South Korea)
2022
National Cancer Institute
2021
Konkuk University Medical Center
2020
Seoul National University Bundang Hospital
2014-2016
The interest of clinical research in aging males increased recent years and thereby the to measure health-related quality life (HRQoL) symptoms men. Aging Males' Symptoms scale (AMS) became most commonly used HRQoL many countries worldwide. aim this paper is review current state instrument particularly concerning versions different languages light translation process.Most translations were performed following international methodological recommendations for linguistic & cultural adaptation...
OBJECTIVES: Assessment of health-related quality life (HRQOL) outcomes in studies liver disease and transplantation is necessary. Reliable valid disease-targeted HRQOL measures are thus needed. The objective this study was to develop a reliable self-report instrument for ambulatory adults with chronic disease. METHODS: Liver Disease Quality Life instrument, LDQOL 1.0 (an measure that uses the SF-36 as generic core 12 multi-item scales) administered multicenter, cross-sectional field test 221...
OBJECTIVES: Assessment of health-related quality life (HRQOL) outcomes in studies liver disease and transplantation is necessary. Reliable valid disease-targeted HRQOL measures are thus needed. The objective this study was to develop a reliable self-report instrument for ambulatory adults with chronic disease. METHODS: Liver Disease Quality Life instrument, LDQOL 1.0 (an measure that uses the SF-36 as generic core 12 multi-item scales) administered multicenter, cross-sectional field test 221...
Objectives. We estimated the prevalence and determinants of delayed unmet needs for medical care among patients in a restructured public health system. Methods. conducted stratified cross-sectional probability sample primary Los Angeles County Department Health Services. Face-to-face interviews were with 1819 adult 6 languages. The response rate was 80%. study racially/ethnically diverse. Results. Thirty-three percent reported delaying needed during preceding 12 months; 25% an need because...
Summary: Purpose : To evaluate relationships between self‐report measures of seizure severity and health‐related quality life (HRQOL) in people with refractory localization‐related epilepsy. Methods A sample 340 adults enrolled a seven‐center, prospective study resective epilepsy surgery completed baseline questionnaires that included the Quality Life Epilepsy (QOLIE)‐89 seven‐item adaptation National Hospital Seizure Severity Scale. Associations QOLIE‐89 summary both total scale score...
<b><i>Objective:</i></b> To evaluate the ability of health-related quality life (HRQOL) measures to detect change over time in persons with epilepsy. <b><i>Background:</i></b> The application HRQOL clinical trials has been limited by a dearth information regarding their abilities measure (i.e., responsiveness). calculate responsiveness, one must categorize subjects as "changed" or "unchanged" priori criteria. <b><i>Methods:</i></b> authors analyzed data collected at baseline and 28-week...
Abstract Background Profiling circulating cell-free DNA (cfDNA) has become a fundamental practice in cancer medicine, but the effectiveness of cfDNA at elucidating tumor-derived molecular features not been systematically compared to standard single-lesion tumor biopsies prospective cohorts patients. The use plasma instead tissue guide therapy is particularly attractive for patients with small cell lung (SCLC), due aggressive clinical course this cancer, which makes obtaining exceedingly...
Neuronal SNARE proteins mediate neurotransmitter release at the synapse by facilitating fusion of vesicles to presynaptic plasma membrane. Cognate v-SNAREs and t-SNAREs from vesicle membrane, respectively, zip up bring about apposition two membranes attached C-terminal ends. Here, we demonstrate that zippering can be modulated in midways wedging with small hydrophobic molecules. Myricetin, which intercalated into inner core near middle complex, stopped motion accumulated trans -complex,...
Abstract Background Distressed individuals in Korea may benefit from the practice of mind–body exercises such as Qigong. However, effectiveness techniques needs to be investigated. Methods Fifty participants who were eligible this study randomized into a group receiving 4-week intervention brief Qigong-based stress reduction program (BQSRP) or wait-list control group. Before and after period, saliva samples collected questionnaires completed on perceived stress, anxiety, “ Hwa-Byung ” (anger...
<i>Background:</i> Systemic treatments for advanced non-small cell lung cancer (NSCLC) have modest survival benefits but high toxicity. Rhus verniciflua Stokes (RVS), the lacquer tree, is an ancient traditional medicine being used treatment of cancer. We investigated efficacy and safety allergen-removed RVS extract (aRVS) prolongation in NSCLC after failure first-line or secondline chemotherapy. <i>Patients Methods:</i> reviewed medical records 40 patients who were treated with aRVS...
Advanced hepatobiliary cancers are highly lethal that require precise prediction in clinical practice. Serum ferritin level increases malignancy and high serum is associated with poor survival various cancers. This study aimed to identify whether could independently predict the overall (OS) of patients advanced cancers.The retrospective cohort was performed by reviewing medical records from June 2006 September 2016. The demographic clinicopathological characteristics as well biochemical...
have been demonstrated in central nervous systems, cardiovascular, endocrine, and immune systems.[1]Much evidence suggests that ginseng can be effective reducing learning deficits memory impairment due to brain damage or aging rodents.[2-10]Furthermore, increases choline acetyltransferase levels the rodent brain,[11-13] significantly long-term potentiation (LTP).[14,15] Neuroprotective properties of ginsenosides also vitro vivo.[2,16] Thus, favorable effects on general function were by...
Chemotherapy improves the survival of patients with advanced non-small cell lung cancer (NSCLC), but tumor progression is often inevitable. Strategies are needed to improve therapeutic efficacy chemotherapy. Over recent years, there has been increasing interest in role maintenance therapy after first-line We investigated and safety standardized allergen-removed Rhus verniciflua Stokes extract (aRVS) as non-progressive disease following reviewed medical records 33 NSCLC, who started treatment...
To evaluate the reliability and validity of Korean version 39-item Parkinson's disease questionnaire (PDQ-39).Cross-cultural adaptation was performed according to international guidelines: forward backward translation, focus group meeting, a field test. With consensus translation produced, validation assessed by evaluating validity. Ninety-three outpatients with (PD) 89 healthy aged controls were recruited. Internal consistency Cronbach's alpha. Validity Spearman correlation analysis, t...
Medical records of patients with advanced non-small cell lung cancer (NSCLC) were retrospectively reviewed to examine the prognostic impact nutritional status on survival. Age, sex, body mass index (BMI), Eastern Cooperative Oncology Group Performance Status (ECOG-PS), histologic tumor type, pulmonary comorbidities, white blood (WBC) count, C-reactive protein (CRP) level, and (PNI) assessed. Overall survival was calculated using Kaplan-Meier analysis compared log-rank testing. Univariate...