A5051219573- Crystallization and Solubility Studies
- Analytical Chemistry and Chromatography
- Chemical and Physical Properties in Aqueous Solutions
- Nanocomposite Films for Food Packaging
- Biochemical Analysis and Sensing Techniques
- Advanced Chemical Sensor Technologies
- Drug Solubulity and Delivery Systems
- Phase Equilibria and Thermodynamics
- Dye analysis and toxicity
- Neuroscience and Neuropharmacology Research
- Nanoparticles: synthesis and applications
- Pharmacological Effects of Natural Compounds
- Molecular Sensors and Ion Detection
- Synthesis and biological activity
- Analytical Chemistry and Sensors
- Ionic liquids properties and applications
- Cancer Mechanisms and Therapy
- Angiogenesis and VEGF in Cancer
- GABA and Rice Research
- Analytical chemistry methods development
- Meat and Animal Product Quality
- Microplastics and Plastic Pollution
Hormozgan University of Medical Sciences
2024
Kurdistan University of Medical Sciences
2024
Tabriz University of Medical Sciences
2017-2022
Tehran University of Medical Sciences
2019-2022
Terbium (Tb) ions have a larger radius, versatile coordination geometry, and high affinity to ligands/drugs containing oxygen or hybrid oxygen-nitrogen atoms. Antenna effect, which is intramolecular energy transfer from the excited triplet states of ligand (donor) emitting level Tb ion (acceptor) in chelates leads strong narrow-band fluorescence with large stokes shift, quantum yields, long decay times. Tb-drug complexes are great importance regarding development sensitive selective...
An important role has been considered for the vascular endothelial growth factor receptor 2 (VEGFR-2) in angiogenesis process, so that its inhibition is an scientific way cancer treatment. In this work, new thienopyrimidine derivatives were synthesized and evaluated. Compared with sorafenib, majority of target compounds had antiproliferative activity against PC3, HepG2, MCF7, SW480, HUVEC cell lines, especially 9h IC50 values 4.5-15.1 μM, confirming noticeable cytotoxic effects on listed...
The solubility of budesonide (BDS) in binary mixtures ethanol and water at T = (293.2–313.2) K is determined mathematically represented using two cosolvency models, i.e. Jouyban–Acree model Jouyban–Acree–van't Hoff model. mean relative deviations for fitting the data BDS + are 6.6% 6.5%, respectively. Furthermore, apparent thermodynamic properties, dissolution enthalpy, entropy, Gibbs free energy change process all mixed solvents were calculated according to van't equations. Dissolution...
The molar solubility of celecoxib (CXB) was measured in the binary mixtures 1-propanol + water at temperatures ranging from 293.2 to 313.2 K. obtained data are mathematically represented by employing five cosolvency models (i.e. van't Hoff equation, Yalkowsky–Roseman model, Jouyban–Acree Jouyban–Acree–van't model and modified Wilson model), mean relative deviations (MRD%) calculated for back-calculated were 2.5%, 68.7%, 12.7%, 12.8% 20.5%, respectively, each investigated model. apparent...
Budesonide (BDS) a steroid-based anti-inflammatory drug widely prescribed for various diseases, has low aqueous solubility. In this study, we investigated cosolvency approach to study the thermodynamic specifications related solubility of BDS at temperature range 293.2-313.2 K in (1-propanol + water) mixtures applying shaking flask method. The predictive power different mathematical models experimental data systems was evaluated. For purpose, linear and nonlinear equations such as van't Hoff...