Zheng Chai

ORCID: 0000-0003-0004-7127
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Acute Myocardial Infarction Research
  • Extracellular vesicles in disease
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Ionosphere and magnetosphere dynamics
  • Global Health Care Issues
  • Aortic Disease and Treatment Approaches
  • Neonatal and fetal brain pathology
  • Coronary Artery Anomalies
  • Traditional Chinese Medicine Studies
  • Thermal Regulation in Medicine
  • Electromagnetic Fields and Biological Effects
  • Advanced MRI Techniques and Applications
  • Atomic and Subatomic Physics Research
  • Healthcare and Venom Research
  • Pericarditis and Cardiac Tamponade
  • Menstrual Health and Disorders
  • Congenital Heart Disease Studies
  • Functional Brain Connectivity Studies
  • Electrospun Nanofibers in Biomedical Applications

Sichuan University
2020-2025

West China Hospital of Sichuan University
2020-2025

Lipid deposition is closely related to the pathogenesis of valvular heart disease (VHD), which a potential target for early diagnosis VHD. However, VHD and valve-specific delivery imaging or therapeutic agents remain challenging. In this work, we hypothesized that lipid droplet-specific probe-loaded nanoparticles simultaneously responsive acidic pH lysosomes could be used as an effective nanosystem precise probes diseased aortic valves in endothelial layer was damaged. A probe, namely,...

10.1039/d5tb00531k article EN Journal of Materials Chemistry B 2025-01-01

Abstract Background The correlation between stable geomagnetic fields and unstable activities with mortality, incidence, prevalence of cardiovascular diseases (CVDs) remains ambiguous. Method To investigate the correlations field (GMF) intensity disturbance (GMD) CVDs events in global, long-period scale, global 204 countries territories were included on base 2019 Global Burden Disease study (GBD 2019). Data GMF intensity, GMD frequency, events, weather health economic indicators from 1996 to...

10.1186/s12889-023-16698-1 article EN cc-by BMC Public Health 2023-09-11

Abstract Background: Tetralogy of Fallot (TOF) is one the most common cyanotic congenital heart diseases. Pulmonary regurgitation and severe comorbidity after transannular patch (TAP) repair TOF patients. It has not been confirmed whether a TAP with monocusp valve reconstruction would benefit patients in perioperative period compared to those without reconstruction. The purpose study review analyze all clinical studies that have outcomes undergoing or conduct preferable surgery. Methods:...

10.21203/rs.3.rs-136099/v1 preprint EN cc-by Research Square (Research Square) 2020-12-29

Abstract Background: Infective endocarditis is a serious infection associated with high mortality. Timely intervention paramount to achieve favorable prognosis in patients endocarditis. At present, the correlation between cardiac troponin level and not well established. Methods: Pubmed, Embase, Cochrane databases were systematically searched for studies examining relationship elevated serum concentration IE. Literature screening, data extraction quality appraisal undertaken by two...

10.21203/rs.3.rs-200322/v1 preprint EN cc-by Research Square (Research Square) 2021-02-09
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