Mao Chen

ORCID: 0000-0002-7352-0563
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About
Contact & Profiles
Research Areas
  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Aortic Disease and Treatment Approaches
  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Cardiac Structural Anomalies and Repair
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Chronic Kidney Disease and Diabetes
  • Coronary Interventions and Diagnostics
  • Blood Pressure and Hypertension Studies
  • Electrospun Nanofibers in Biomedical Applications
  • Psoriasis: Treatment and Pathogenesis
  • Congenital Heart Disease Studies
  • Lipoproteins and Cardiovascular Health
  • Cardiovascular Disease and Adiposity
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiovascular Syncope and Autonomic Disorders
  • Analytical Chemistry and Sensors
  • Porphyrin and Phthalocyanine Chemistry
  • COVID-19 Clinical Research Studies
  • Cardiomyopathy and Myosin Studies
  • Heart Failure Treatment and Management
  • Cardiovascular Effects of Exercise

Sichuan University
2016-2025

West China Hospital of Sichuan University
2016-2025

Xinqiao Hospital
2024

Army Medical University
2024

Chengdu University
2021

A lipid droplets (LDs) specific fluorescent probe TTIE is prepared for LDs image-guided photodynamic therapy (PDT), which can light up the in human clear cell renal carcinoma cells and tissues, kill tumor <italic>via</italic> PDT process.

10.1039/d0cc07336a article EN Chemical Communications 2021-01-01

Severe degenerative mitral regurgitation (DMR) can cause a poor prognosis if left untreated. For patients considered at prohibitive surgical risk, transcatheter edge-to-edge repair (TEER) has become an accepted alternative therapy. The DragonFly valve system is innovative evolution of the TEER device family to treat DMR.

10.4244/eij-d-23-00361 article EN EuroIntervention 2024-02-01

Myocardial ischemia-reperfusion injury (MIRI) often leads to irreversible myocardium dysfunction, while existing therapies are palliatives that transiently alleviate the disease symptoms. Repairing sarcoplasmic reticulum Ca 2+ -ATPase (SERCA) could reverse MIRI, which, however, requires precise drug delivery (SR). To this end, we leverage cell-cell “NETwork” of neutrophils deliver SERCA activator-loaded SR-localized nanoparticles (L-P-NPs) damaged myocardial cells, following a hierarchical...

10.1126/sciadv.adr4333 article EN cc-by-nc Science Advances 2025-02-12

This study was aimed to investigate the associations of serum calcium, phosphate, and vitamin D levels with risk developing aortic stenosis (AS).We included 296 415 participants who were free prior diagnosis any valvular heart disease from UK Biobank. Serum measured. Incidental AS determined by records hospital data. Cox regression used examine association mineral incidental after adjustment for potential confounders. The mean age 56.4 years (SD 8.14) 53.3% women. During an average follow-up...

10.1093/eurjpc/zwac016 article EN European Journal of Preventive Cardiology 2022-01-26

Permanent pacemaker implantation and left bundle branch block are common complications after transcatheter aortic valve replacement (TAVR) associated with impaired prognosis. This study aimed to develop an artificial intelligence (AI) model for predicting conduction disturbances TAVR using pre-procedural 12-lead electrocardiogram (ECG) images. We collected ECGs of patients who underwent at West China Hospital between March 2016 2022. A hold-out testing set comprising 20% the sample was...

10.1093/ehjdh/ztae007 article EN cc-by European Heart Journal - Digital Health 2024-02-08

Abstract Background Percutaneous pulmonary valve implantation (PPVI) with the self‐expandable Venus P‐valve system is a promising treatment for patients regurgitation (PR) and native right ventricular outflow tract (RVOT). However, limited data available regarding its midterm outcomes. This study assessed clinical echocardiographic outcomes following implantation. Methods From 2013 to 2018, 55 moderate or severe PR after surgical RVOT repair transannular patch were consecutively enrolled...

10.1002/ccd.30916 article EN Catheterization and Cardiovascular Interventions 2023-12-06

Correction for ‘A lipid droplet targeted fluorescent probe high-efficiency image-guided photodynamic therapy of renal cell carcinoma’ by Ping Tan <italic>et al.</italic>, <italic>Chem. Commun.</italic>, 2021, DOI: 10.1039/d0cc07336a.

10.1039/d1cc90021h article EN cc-by Chemical Communications 2021-01-01

Data concerning the outcomes of transcatheter aortic valve replacement in type 0 bicuspid stenosis (AS) are scarce. The study aims to compare for AS patients with bicuspid, 1 and tricuspid anatomy. We enrolled consecutive undergoing severe between 2012 2022 this single-center retrospective cohort study. primary outcome was mortality, while secondary included in-hospital complications such as stroke pacemaker implantation heart hemodynamic performance. number anatomy 328, 302, 642,...

10.1161/circinterventions.123.013083 article EN Circulation Cardiovascular Interventions 2023-10-17

Elderly patients with coronary artery disease (CAD) frequently complicated more cardiovascular risk factors, but received fewer evidence-based medications (EBMs). This study explored the association of EBMs compliance in different age groups and long-term death. A retrospective analysis was conducted from a single registered database. 2830 consecutive CAD were enrolled grouped into 3 categories by age. The primary end point all-cause mortality secondary endpoint is mortality. mean follow-up...

10.1186/s12889-018-5049-x article EN cc-by BMC Public Health 2018-01-17
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