A5050909200- Renal and related cancers
- Ocular Oncology and Treatments
- Renal cell carcinoma treatment
- Acute Myeloid Leukemia Research
- Acute Lymphoblastic Leukemia research
- Pediatric Urology and Nephrology Studies
- Ocular Infections and Treatments
- Retinal and Macular Surgery
- Genetic and Kidney Cyst Diseases
- Genomics and Rare Diseases
- Retinoids in leukemia and cellular processes
- Hematopoietic Stem Cell Transplantation
- Cancer-related Molecular Pathways
- Chronic Myeloid Leukemia Treatments
- RNA modifications and cancer
- Neuroblastoma Research and Treatments
- Ubiquitin and proteasome pathways
- Radiation Dose and Imaging
- Ethics and Legal Issues in Pediatric Healthcare
- Nitrogen and Sulfur Effects on Brassica
- COVID-19 and healthcare impacts
- Hedgehog Signaling Pathway Studies
- Bone and Joint Diseases
- Immune cells in cancer
- Cancer, Hypoxia, and Metabolism
Grupo Santa Casa de Belo Horizonte
2011-2023
Santa Casa Hospital
2023
Fundação Centro de Hematologia e Hemoterapia de Minas Gerais
2015
AC Camargo Hospital
2006
Universidade Federal de Minas Gerais
2006
ABSTRACT Objectives: We evaluated the efficacy of cognitive‐behavioral family intervention in treatment crises pain children with nonorganic recurrent abdominal (RAP) and thresholds for 17 body surface areas these children. Methods: A randomized clinical trial was undertaken 32 between ages 5.1 13.9 years RAP. group 15 patients, aged 9.9 ± 2.2 (11 girls), received standard pediatric care crises. The control children, 8.4 2.0 only care. These procedures were by general pediatricians over 4...
PURPOSE International comparisons of patient demographics, tumor characteristics, and survival can shed light on areas for health care system improvement. The Society Pediatric Oncology Wilms Tumor 2001 trial/study registered patients through national clinical study groups in Western Europe Brazil. This retrospective post hoc analysis the database aims to make visible suggest reasons any variations outcomes. METHODS All with unilateral (WT), age > 6 months, treated preoperative...
Retinoblastoma is a malignant tumor of the embryonic neural retina. About 80% cases are diagnosed before age 4, with median at diagnosis 2 years.To determine characteristics and prognosis retinoblastoma in children older than 5 years.From 1986 to 2002, medical records 16 patients out 453 referred Hospital do Câncer AC Camargo, São Paulo, Brazil.Median was 73.7 months (range 65-144) there an equal gender distribution. Fifteen presented unilateral disease. The mean time between first symptoms...
Abstract Local therapies are increasingly used for ocular preservation in retinoblastoma. In middle‐income countries, these techniques pose specific challenges mostly related to more advanced disease at diagnosis. The Grupo de America Latina Oncología Pediátrica (GALOP) developed a consensus document the management of conservative therapy Intra‐arterial chemotherapy (OAC) is preferred therapy, except those with less or age younger than 6 months. OAC allowed reduction use external beam...
The ultrarare hepatoblastoma (HB) is the most common pediatric liver cancer. HB risk related to a few rare syndromes, and molecular bases remain elusive for cases. We investigated burden of damaging germline variants in 30 Brazilian patients with presence additional clinical signs. A high frequency prematurity (20%) birth defects (37%), especially craniofacial (17%, including craniosynostosis) kidney (7%) anomalies, was observed. Putative pathogenic or likely monoallelic mapped 10 cancer...
The COVID-19 pandemic had global catastrophic effects on the management of non-communicable diseases including paediatric cancers. Restrictions during start 2020 complicated timely referrals patients to specialized centres. We aimed evaluate pandemic's impact number new diagnoses, disease characteristics and delay for renal tumour included in SIOP-RTSG-UMBRELLA study, as compared with data from a historical SIOP-RTSG trial (2005-2009).The intensive care admissions, population mobility rates...
Background/Aims: Cytogenetic and molecular genetics play a pivotal role in treatment of acute leukemias. We prospectively evaluated genetic alterations Brazilian patients with myeloid leukemia (AML) or lymphoblastic (ALL) their association clinical laboratorial data. Methods: Flow cytometry, conventional cytogenetics (CC), FISH, PCR, RT-PCR sequencing were performed on samples from 161 de novo ALL 155 AML. Results: Main CC findings AML t(15;17) (19.4%), +8 (17.4%), complex karyotype (14.6%),...
Abstract Neuroblastoma (NB) is a rare childhood cancer typically affecting children under five and arising from neural crest sympathoadrenal linage cells. Despite its rarity, it the most frequent solid tumor in five. Determination of circulating immune response NB before treatment has begun can help identification potential cells pathways involved disease development suitability for immunotherapy. These studies were designed to investigate cellular soluble (cytokines) using flow cytometry...
Local therapies replaced systemic chemotherapy for ocular preservation in retinoblastoma. In middle income countries, these techniques pose specific challenges mostly related to more advanced disease at diagnosis. The Grupo de America Latina Oncologia Pediatrica (GALOP developed a consensus document the management of conservative therapy Intra-arterial (OAC) is preferred therapy, except those with less or age younger than 6 months. OAC allowed elimination use external beam radiotherapy our...
The ultrarare hepatoblastoma is the most common pediatric liver cancer. HB risk related to a few rare syndromes, and molecular bases remain elusive for cases. We investigated burden of damaging germline variants in 30 Brazilian patients with HB. A high frequency prematurity (20%) birth defects (37%), especially craniofacial (17%, including craniosynostosis) kidney (7%) anomalies, was observed. Pathogenic or likely pathogenic mapped 10 cancer predisposition genes (APC, CHEK2, DROSHA, ERCC5,...