A5030636638- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Ginseng Biological Effects and Applications
- Natural product bioactivities and synthesis
- Phytochemical compounds biological activities
- Phytochemistry and Bioactivity Studies
- Fungal Biology and Applications
- Microbial Natural Products and Biosynthesis
- Plant-based Medicinal Research
- Phytochemistry and biological activity of medicinal plants
- Food Quality and Safety Studies
- Metabolomics and Mass Spectrometry Studies
Hebei University of Chinese Medicine
2021-2023
Objective: To investigate the differences in odor characteristics and volatile components between raw wine‐processed Chuanxiong Rhizoma to establish a rapid differentiation method based on taste, smell, color, chemical components. Methods: Electronic tongue, electronic nose, ultraviolet spectrophotometer were used analyze 23 batches of Rhizoma. Principal component analysis, one‐way ANOVA, orthogonal partial least‐squares discriminant analysis employed differentiate alcoholic Headspace gas...
Phyllanthus emblica L. is widely used in traditional Tibetan medicine for its therapeutic effects on treating liver, kidney, and bladder problems. We have reported that the tannin fraction has a good anti-hepatocellular carcinoma effect, but active ingredients are not clear. This study was to find of using UPLC-MSn network pharmacology. First all, method employed obtain high-resolution mass spectra different components, 110 compounds were obtained. Then pharmacology biomarkers quality...
As a classic TCM prescription, LGZG has been widely used in clinical prevention and treatment of heart failure, nonalcoholic fatty liver, hyperlipidemia. However, there are few studies on chemical components recent years, the basis quality evaluation is not sufficient. This study was to find active ingredients Lingguizhugan decoction using UPLC-MS/MS network pharmacology. By comparing retention time MS dates reference self-building database, cleavage rules composition whose mass errors less...
Shaoyao Gancao Decoction (SGD) is a classic prescription of traditional Chinese medicine (TCM), which composed Paeoniae Radix Alba and Glycyrrhizae et Rhizoma, has the clinical effect anti-liver injury, but its active ingredients are unclear. In this study, joint application phytochemical compositional analysis, network pharmacology, molecular docking technology was utilized to screen components SGD against liver injury. Firstly, total 110 compounds were identified by UPLC-Q-TOF-MS/MS,...
Four new meroterpenoids, Clavilactone M-P, possessing novel aminoglycoside moiety (1-4) and a 10-membered carbocycle fused with an α,β-epoxy-γ-lactone, were isolated from Clitocybe clavipes, basidiomycete. Their structures absolute configurations determined by extensive analysis of their spectroscopic data, the ECD method. All compounds evaluated for antitumor activity against three human cancer cell lines using MTT assay. Compound 1 2 exhibited significant suppression viability in Hela...