A5100457929- Advanced Operator Algebra Research
- Acne and Rosacea Treatments and Effects
- Nanoplatforms for cancer theranostics
- Radiomics and Machine Learning in Medical Imaging
- Nanoparticle-Based Drug Delivery
- Advanced Topics in Algebra
- Dermatologic Treatments and Research
- Lanthanide and Transition Metal Complexes
- Glioma Diagnosis and Treatment
- Advanced Banach Space Theory
- Renal cell carcinoma treatment
- AI in cancer detection
- Pharmacological Effects of Natural Compounds
- Luminescence Properties of Advanced Materials
- Algebraic structures and combinatorial models
- Herpesvirus Infections and Treatments
- MRI in cancer diagnosis
- Holomorphic and Operator Theory
- melanin and skin pigmentation
- Homotopy and Cohomology in Algebraic Topology
- Advanced Neural Network Applications
- Pancreatic and Hepatic Oncology Research
- Radiation Dose and Imaging
- Nanocluster Synthesis and Applications
- Advanced Neuroimaging Techniques and Applications
Capital University
2025
Huashan Hospital
2016-2025
Fudan University
2016-2025
Chinese Academy of Fishery Sciences
2025
Capital Medical University
2025
Beijing Sport University
2023-2024
Nanjing Medical University
2019-2024
Donghua University
2024
Jiangsu Province Hospital
2019-2024
Nanjing University of Chinese Medicine
2022-2024
Metallic glasses and cancer theranostics are emerging fields that do not seem to be related each other. Herein, we report the facile synthesis of amorphous iron nanoparticles (AFeNPs) their superior physicochemical properties compared crystalline counterpart, nanocrystals (FeNCs). The AFeNPs can used for by inducing a Fenton reaction in tumor taking advantage mild acidity overproduced H2 O2 microenvironment: Ionization enables on-demand ferrous ion release tumor, subsequent...
Several decades of research have identified the specific tumor microenvironment (TME) to develop promising nanotheranostics, such as pH-sensitive imaging, acidity-sensitive starving therapy, and hydrogen peroxide-activated chemotherapy, etc. Herein, a novel TME-mediated nanoplatform employing antiferromagnetic pyrite nanocubes is presented, exploiting intratumoral, overproduced peroxide for self-enhanced magnetic resonance imaging (MRI) photothermal therapy (PTT)/chemodynamic (CDT). Through...
Surgical resection, one of the main clinical treatments intracranial glioblastoma, bears potential risk incomplete excision due to inherent infiltrative character glioblastoma. To maximize accuracy surgical magnetic resonance (MR) and fluorescence imaging are widely used for tumor preoperative diagnosis intraoperative positioning. However, present commercial MR contrast agents fluorescent dyes can only function single mode subject poor blood–brain barrier (BBB) permeability...
Abstract Metallic glasses and cancer theranostics are emerging fields that do not seem to be related each other. Herein, we report the facile synthesis of amorphous iron nanoparticles (AFeNPs) their superior physicochemical properties compared crystalline counterpart, nanocrystals (FeNCs). The AFeNPs can used for by inducing a Fenton reaction in tumor taking advantage mild acidity overproduced H 2 O microenvironment: Ionization enables on‐demand ferrous ion release tumor, subsequent...
Gd3+-based contrast agents (CAs) are the most prevailing and widely used for enhanced magnetic resonance imaging (MRI). Numbers of approaches have been developed to regulate key parameters in order obtain high-relaxivity CAs, according classic Solomon–Bloembergen–Morgen theory. Herein, a method controlling oxygen vacancies inorganic nanosized CAs has largely accelerated proton relaxation high r1 value. Such strategy is verified on oxygen-deficient PEG-NaxGdWO3 nanorods, which exhibit...
In recent decades, extensive attention has been paid to developing anatomic and functional imaging contrast agents that could provide a wealth of complementary bioimaging information. Among them, dual-mode nanoprobes combine magnetic resonance (MRI) with fluorescent have mostly used for separated imaging. However, the lack machine simultaneous greatly limits further clinical application. One effective strategy is rationally design MRI own both MR capability on single machine, which highly...
Background Rosacea, a chronic inflammatory skin disorder etiologically associated with immune cells and the antibacterial peptide cathelicidin LL-37, can be effectively treated by oral carvedilol administration. Objective To investigate molecular mechanisms underlying efficacy in rosacea treatment. Methods Skin samples of patients were subjected to histopathological (hematoxylin eosin) immunohistochemical (CD68, Toll-like receptor 2 (TLR2), kallikrein 5, cathelicidin, TNF-α, IL-1β)...
The central nervous system (CNS) maintains homeostasis with its surrounding environment by restricting the ingress of large hydrophilic molecules, immune cells, pathogens, and other external harmful substances to brain. This function relies heavily on blood-cerebrospinal fluid (B-CSF) blood-brain barrier (BBB). Although considerable research has examined structure BBB, B-CSF received little attention. Therapies for disorders associated have potential benefit from targeting enhance medication...
Abstract Mesenchymal stem cells (MSCs) transplantation is a promising therapeutic strategy for ischemic stroke. However, the survival of transplanted MSCs often compromised by excessive levels reactive oxygen species (ROS) and calcium ions (Ca 2+ ) in microenvironment following blood flow occlusion. In this study, protective developed using functional nanomaterials to escort shield MSCs. Specifically, NaGdF 4 @PDA‐ALD nanoparticles (NPANs) are synthesized, featuring core coated with...
<title>Abstract</title> Bee pollen and its extracts have been used for decades as therapeutic agents or health food supplements to alleviate chronic non-bacterial prostatitis (CNP). However, functional compounds in bee on anti-CNP remain still unclear. In this study, we evaluated the properties of six principal phenolamides pollen. Our results provide compelling evidence that property may be ascribed abundance phenolamides. Particularly, di-<italic>p</italic>-Coumaroyl spermidine can CNP by...
Abstract Osteosarcoma, as the most common primary bone cancer, is difficult to make a differentiation between tumor with contrast agents (CAs) accumulation and healthy bones using X‐ray computed tomography (CT) since they both display high attenuation of X‐ray. Recently, an advanced CT form, gemstone spectral (GSCT), has received extensive attention due its significant ability material decomposition monochromatic images, which can overcome above disadvantages conventional CT. Herein,...
To construct and verify a CT-based multidimensional nomogram for the evaluation of lymph node (LN) status in pancreatic ductal adenocarcinoma (PDAC).