- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Animal Genetics and Reproduction
- Aquaculture Nutrition and Growth
- MicroRNA in disease regulation
- Sperm and Testicular Function
- Muscle Physiology and Disorders
- Advanced Battery Materials and Technologies
- RNA Research and Splicing
- Developmental Biology and Gene Regulation
- Molecular Biology Techniques and Applications
- Genetic diversity and population structure
- RNA Interference and Gene Delivery
- Guidance and Control Systems
- CRISPR and Genetic Engineering
- Adaptive Control of Nonlinear Systems
- Reproductive Biology and Fertility
- Cancer-related molecular mechanisms research
- Robotic Path Planning Algorithms
- Circular RNAs in diseases
- Genetics, Aging, and Longevity in Model Organisms
- FOXO transcription factor regulation
- FinTech, Crowdfunding, Digital Finance
- Advanced battery technologies research
- Fibroblast Growth Factor Research
Ocean University of China
2019-2025
Dalian University of Technology
2024
Hainan Tropical Ocean University
2024
Peking University
2023
State Key Laboratory of Turbulence and Complex Systems
2023
Beijing University of Chemical Technology
2022-2023
Pepperdine University
2023
Qingdao University
2022
Qingdao Women and Children's Hospital
2022
Beijing Institute of Technology
2022
Teleost fish are the most diverse group of vertebrates and provide opportunities to study evolution sex determination (SD) systems. Using genomic functional analyses, we identified a male-specific duplication anti-Müllerian hormone ( amh ) gene as male master sex-determining (MSD) in Sebastes schlegelii . By resequencing 10 males females, characterized 5 kb-long fragment HiC_Scaffold_12 region, which contained an (named amhy ). We then demonstrated that is autosomal was later translocated...
A polyamino acid with zincophilic chains is introduced as a multifunctional electrolyte additive for uniform Zn deposition and inhibition of side reactions.
The black rockfish (Sebastes schlegelii) is a teleost in which eggs are fertilized internally and retained the maternal reproductive system, where they undergo development until live birth (viviparity). In present study, we report chromosome-level genome assembly. High-throughput transcriptome analysis (RNA-seq ATAC-seq) coupled with situ hybridization (ISH) immunofluorescence reveal several candidate genes for preparation, sperm storage release, hatching. We propose that zona pellucida (ZP)...
ABSTRACT Teleost testis development during the annual cycle involves dramatic changes in cellular compositions and molecular events. In this study, testicular cells derived from adult black rockfish at distinct stages – regressed, regenerating differentiating were meticulously dissected via single-cell transcriptome sequencing. A continuous developmental trajectory of spermatogenic cells, spermatogonia to spermatids, was delineated, elucidating events involved spermatogenesis. Subsequently,...
Ladderlectin, a teleost-specific C-type lectin, has been primarily associated with innate immune defense. However, this study unveils an important role of ladderlectin in the reproductive processes Sebastes schlegelii. Seven genes (SscLLs) are identified, SscLL3604 and SscLL3605 exhibiting high testis-specificity expression. Both contain lectin domain (CTLD) two carbohydrate-binding motifs (QPD WSD), also containing signal peptide. Notably, is predominantly cytoplasmic, while found both...
Alzheimer's disease is a common neurodegenerative characterized by progressive cognitive dysfunction and behavioral impairment. Aerial parts of Polygala tenuifolia Willd (APT) traditional Chinese medicine used for the treatment amnesia. The present study aimed to investigate protective effects APT on scopolamine-induced learning memory impairments in mice. Scopolamine-induced mice were determine Mice orally administered with (25, 50 100 mg/kg) piracetam (750 14 days, intraperitoneally...
Pax3 and Pax7 are members of the Pax gene family which essential for embryo organ development. Both genes have been proved to be markers muscle satellite cells play key roles in process growth repair. Here, we identified two (SsPax3a SsPax3b) (SsPax7a SsPax7b) a marine teleost, black rockfish (Sebastes schlegelii). Our results showed SsPax3 SsPax7 marked distinct populations cells, originated from multi-cell stage somite stage, respectively. In addition, constructed injury model explore...
Fibroblast growth factors (FGFs) are short polypeptides that play essential roles in various cellular biological processes, including cell migration, proliferation, and differentiation, as well tissue regeneration, immune response, organogenesis. However, studies focusing on the characterization function of FGF genes teleost fishes still limited. In this study, we identified characterized expression patterns 24 tissues embryonic adult specimens black rockfish (Sebates schlegelii). Nine were...
In some vertebrates and invertebrates, semen release factors affecting female physiology behavior. Here, we report that delivered to females is potentially beneficial for promoting oocyte development in a viviparous teleost, Sebastes schlegelii. 88% of mated ovaries develop normally give birth larval fish, whereas 61% non-mated are arrested the previtellogenic stage. Semen's significant role (p < 0.0001) may involve remodeling follicular cells regulating expression extracellular matrix,...
In the present study, PLC characteristic parameters and DSA mechanism of Al-(2.86~9.41) Mg alloy sheets were investigated during tensile testing at room temperature with a rate 1 × 10-3 s-1. On basis solution concentrations in α-Al matrix, initial vacancy concentration, second-phase particle configuration recrystallized grain are almost same by quenching treatment. The results show that type room-temperature stress-strain curves quenched varied according to content. curve Al-2.86 sheet was B...
Abstract The cyp11 includes cyp11a and cyp11b in most mammals teleosts, encoded cholesterol side chain lyase 11β‐hydroxylase, respectively. It is essential steroid hormone synthesis. However, studies on the regulation of are limited, especially teleosts. In this study, molecular characterization function black rockfish was investigated. Both them showed high homology with other teleost counterparts by phylogenetic analysis. expression exhibited a clear sexually dimorphic pattern, higher...
Myosins are important eukaryotic motor proteins that bind actin and utilize the energy of ATP hydrolysis to perform a broad range functions such as muscle contraction, cell migration, cytokinesis, intracellular trafficking. However, characterization function myosin is poorly studied in teleost fish. In this study, we identified 60 family genes marine teleost, black rockfish (Sebastes schlegelii), further characterized their expression patterns. showed divergent patterns adult tissues,...
Abstract The Collagen Type VII Alpha 1 Chain (COL7A1) is associated with a variety of cancers, however, COL7A1 gene expression in human lung squamous cell carcinoma (LUSC) and its prognostic value have not been well studied. In this study, we used bioinformatics database to analyze the relationship between survival LUSC patients such as Oncomine, GEPIA, UALCAN, STRING. And Kaplan–Meier plotter prognosis high or low different patients. We found that was significantly overexpressed LUSC....
During the operation of magnetic bearing, there is an unbalanced component in displacement signal at same frequency as rotational speed, which produces stiffness force speed to affect performance control system, so it necessary suppress bearing force. Due influence sensor runout and nonlinear characteristics bearings, also a multiplication signal, view above problems, feed-forward compensation method for considering harmonic disturbance proposed, suppressed by second-order generalized...