A5078869264- Medical Imaging and Pathology Studies
- Thyroid Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Bone health and treatments
- Radiomics and Machine Learning in Medical Imaging
- Lymphoma Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Sarcoma Diagnosis and Treatment
- Hematological disorders and diagnostics
- Breast Lesions and Carcinomas
- Sarcoidosis and Beryllium Toxicity Research
- Thyroid and Parathyroid Surgery
- CNS Lymphoma Diagnosis and Treatment
- Bone health and osteoporosis research
- Intraperitoneal and Appendiceal Malignancies
- Orthopedic Infections and Treatments
- Histiocytic Disorders and Treatments
- Breast Cancer Treatment Studies
- Bone Tumor Diagnosis and Treatments
- Ovarian cancer diagnosis and treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Testicular diseases and treatments
- BRCA gene mutations in cancer
- Machine Learning in Healthcare
Shaukat Khanum Memorial Cancer Hospital and Research Center
2016-2025
Society of Nuclear Medicine and Molecular Imaging
2020
CMH Lahore Medical College and Institute of Dentistry
2018
Edward Hines, Jr. VA Hospital
2010-2014
Hospital of the University of Pennsylvania
2002
Radium Hemmets Research Funds
1990
Pulmonary embolism (PE) can lead to chronic thromboembolic pulmonary hypertension (CTEPH) which resultin right heart failure. Therefore, timely management of this condition save patients from serious complications.In the department Nuclear Medicine, ventilation perfusion (V/Q) scan has been used supplement detection ofPE especially in cases where contrast based computed tomography angiography (CTPA) cannot beperformed. With advent single photon emission (SPECT/CT), withSPECT/CT is being...
Erdheim-Chester Disease (ECD) is a rare systemic histiocytic disorder characterized by symmetrical skeletal involvementand variable visceral manifestations. Tc-99m MDP bone scintigraphy, CT, MRI, and FDG PET-CT are essential for diagnosisand disease mapping. ECD’s course depends on extraosseous involvement, with potential complications including heartand renal failure. We present the case of ECD bilateral leg pain orbital involvement. Imaging revealed mixed scleroticand lytic lesions,...
Deep neural networks are increasingly crucial for analysing dynamic functional brain imaging data, offering unprecedented accuracy in distinguishing activity patterns across health and disease. However, they often function as black boxes obscuring the neurobiological features driving classifications between groups. This study systematically investigates explainable AI (xAI) methods to address this challenge, employing two complementary simulation approaches: recurrent controlled parameter...
Background: Prostate cancer, the 2nd most frequent cancer-related death among males in United States, is primarily found male reproductive organ. Aim: To evaluate role of PSMA PET/CT-derived volumetric quantitative parameters prostate cancer patient follow-up, assessing their precision and correlation with PSA levels. Patients methods: This prospective investigation involved 98 cases pathologically proven well-differentiated cancer. The study would be conducted Nuclear Medicine Radiation...
Nuclear medicine is an essential tool in the delivery of high-quality medical care, going beyond simple anatomic imaging to use physiologic processes for both and therapy. One first uses nuclear techniques occurred 1930s demonstrate physiology
Sixteen consecutive patients with anaplastic carcinoma of the thyroid were prospectively treated according to a combined regimen consisting hyperfractionated radiotherapy, doxorubicin and debulking surgery. The radiotherapy was preoperatively administered target dose 30 Gy in 3 weeks, postoperatively an additional 16 1.5 weeks. Radiotherapy twice daily, 5 days week, 1 per fraction minimum interval 6 hours. A 20 mg intravenously 2 hours before first session every week. Debulking surgery...
Although iodinated radiopharmaceuticals usually contain a small quantity of unbound iodine, it is difficult to establish the degree which thyroid activity on scintigraphic images reflects uptake free radioiodine. The objective present study was examine effectiveness blockade in subjects undergoing <sup>123</sup>I-<i>meta</i>-iodobenzylguanidine (<i>m</i>IBG) imaging and estimate relative contribution bound radioiodine findings. <b>Methods:</b> All were participants prospective trials...
The aim of this study was to evaluate the overall and progression-free survival papillary thyroid carcinoma (PTC), comparing American Thyroid Association (ATA) guideline for risk recurrence with TNM staging system dynamic assessment at 2 years.This is a retrospective analysis 689 PTC patients over 20-year period single center. Disease-free based on ATA calculated using Kaplan-Meier curves. Dynamic response during first years compared both systems. Survival age, baseline resectability,...
There are no positron emission tomography (PET) studies reported in the literature with regards to brain metabolism and function patients Lyme disease. These frequently present various neurological symptoms, including memory problems. We used [18F]fluorodeoxyglucose (FDG) PET determine metabolic landscape 23 Images were evaluated for cortical subcortical abnormalities by two experienced reviewers blinded clinical information. The most striking finding was hypometabolism temporal lobes 17/23...
To evaluate the overall and progression-free survival for follicular thyroid carcinoma (FTC) based on American Thyroid Association (ATA) staging system recurrence risk assessment TNM system.A clinical review of FTC patients between 1995 2014 was conducted at a single center. The data classified using into low, intermediate, high as per ATA assessment.Over course 19 years, 114 (11.9%) all cancer presenting to our hospital had (i.e. 78 females 36 males). age range 15-80 years. Ninety-four...
To evaluate the prevalence of malignancy in incidental thyroidal uptake on PET with fluorine-18 deoxyglucose integrated computed tomography (F-FDG PET/CT) Pakistani cancer patients and to assess role standardized value (SUV) deciding which lesions investigate further.We retrospectively reviewed all who underwent F-FDG PET/CT scans over a period 59 months further analysed those visually increased uptake. Uptake was classified as focal or diffuse.Out 10 012 done for evaluation known,...
Intravenous tumor extension is a well-recognized phenomenon occurring in various malignancies but relatively rare entity thyroid carcinoma. In patients with poorly differentiated cancer (pDTC), I-131 avid superior vena cava (SVC) thrombus at initial presentation infrequent and potential life threatening. Tumor can form either due to direct vascular of the primary mass or by hematogenous spread. Hybrid nuclear imaging differentiate two entities, which impact treatment plan patient. We present...
Objective: The aim of this study was to compare the TNM staging system and American Thyroid Association (ATA) recurrence risk classification in predicting radioiodine refractory disease (RRD) differentiated thyroid cancer (DTC) analyze correlation stimulated thyroglobulin (Tg) levels rate Tg elevation with standardized uptake value on <sup>18</sup>F-fludeoxyglucose (FDG) PET/CT scan. Methods: RRD indicated through retrospective analysis consecutive <sup>18</sup>F-FDG scans DTC >10 ng/ml...
Melorheostosis is a benign, noninheritable bone dysplasia characterized by its classic radiographic features of dense, flowing hyperostosis. It frequently affects one limb, usually the lower extremity and rarely axial skeleton. A 26-year-old lady with obesity, polycystic ovarian syndrome scalp dandruff presented long standing history upper pain inability to adduct arm completely. Tc-99m MDP whole body SPECT/CT scan performed for suspected fibrous showed increased radiotracer uptake in...
Abstract To compare the detection efficacy of radionuclide lymphoscintigraphy (LS) versus patent blue dye (PBD) technique for hidden sentinel lymph node (SLN) in breast cancer patients and to determine which modality is better SLN detection. One hundred thirty-four early stage female with clinically negative axilla who underwent post technetium-99m nanocolloid injection single photon emission computed tomography (SPECT-CT) on planar imaging were studied prospectively between 2015 2017....
The objective of this study was to identify the characteristic features patients with distant metastasis as only manifestation well-differentiated thyroid cancers and analyze treatment outcomes.A retrospective review all sole initial presentation carried out. Data regarding age, gender, tumor histology, site, symptoms, outcomes were collected.There 10 who presented presentation. mean age 56.1 years. Eight (80%) had osseous metastasis, one (10%) pulmonary both. Follicular carcinoma more...
Hypermetabolic Hurthle Cell Adenoma on 18 F-FDG PET/CT