Arun Kumar De

ORCID: 0000-0003-0083-9300
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About
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Research Areas
  • Genetic and phenotypic traits in livestock
  • Effects of Environmental Stressors on Livestock
  • Reproductive Biology and Fertility
  • Reproductive Physiology in Livestock
  • Livestock Management and Performance Improvement
  • Pluripotent Stem Cells Research
  • Livestock and Poultry Management
  • Animal Nutrition and Physiology
  • Animal Genetics and Reproduction
  • Genomics and Phylogenetic Studies
  • Genetic diversity and population structure
  • Sperm and Testicular Function
  • Cancer Cells and Metastasis
  • Identification and Quantification in Food
  • Helminth infection and control
  • Genetic Mapping and Diversity in Plants and Animals
  • Forensic Entomology and Diptera Studies
  • Marine Sponges and Natural Products
  • Animal Diversity and Health Studies
  • Animal Disease Management and Epidemiology
  • Viral Infections and Vectors
  • RNA modifications and cancer
  • Parasitic infections in humans and animals
  • Liver physiology and pathology
  • Parasite Biology and Host Interactions

ICAR - Central Island Agricultural Research Institute
2016-2025

Medical College and Hospital, Kolkata
2009-2024

Institute of Post Graduate Medical Education and Research
2024

Indian Council of Agricultural Research
2013-2024

Borneo Orangutan Survival Foundation
2022

Midnapore Medical College and Hospital
2016-2018

University of Illinois Urbana-Champaign
2013-2018

Carle Foundation Hospital
2017

University of Illinois System
2014-2016

KPC Medical College and Hospital
2010-2014

Repurposing of existing cancer drugs to overcome their physical limitations, such as insolubility, represents an attractive strategy achieve enhanced therapeutic efficacy and broaden the range clinical applications. Such approach also promises offer substantial cost savings in drug development efforts. Here we repurposed FDA-approved topical agent bexarotene (Targretin), currently limited use for cutaneous manifestations T-cell lymphomas, re-engineer it solid tumor applications by forming...

10.1021/acsnano.5b05974 article EN ACS Nano 2015-10-05

// Kyle M. Schachtschneider 1, 2, 3 , Regina Schwind Kwame A. Darfour-Oduro 1 Arun K. De Lauretta Rund Kuldeep Singh 4 Daniel R. Principe 5 Grace Guzman 6 Charles E. Ray Jr. 3, 7 Howard Ozer Ron C. Gaba and Lawrence B. Schook Department of Animal Sciences, University Illinois, Urbana, IL, USA 2 Breeding Genomics Centre, Wageningen University, Wageningen, The Netherlands Radiology, Illinois at Chicago, Veterinary Diagnostic Laboratory, College Medicine, Pathology, Division...

10.18632/oncotarget.18872 article EN Oncotarget 2017-06-29

The study was conducted to detect the occurrence and phenotypic resistance pattern of ESBL-producing Enterobacteriaceae in livestock using docking based analysis reveal classes antibiotics against which ESBL-producers are active. Rectal swabs from healthy cattle (n=100), goats (n=88), pigs (n=66) were collected backyard farms Andaman Nicober island (India). In total, 304 isolates comprising E. coli (131), Salmonella (75), Klebsiella penumoniae (98) recovered. showed that highest found...

10.1093/lambio/ovaf003 article EN Letters in Applied Microbiology 2025-01-17

To improve our knowledge on host-parasite interaction, the study was undertaken Rhipicephalus microplus infestation in cross breed cattle. This tick, being a voracious blood sucker, remains attached to skin for prolonged period and inoculates saliva during feeding. Biomolecules present have detrimental effects host system. The deals with of R. artificially infected nine months old cattle 21 days. There physiological alteration tick terms body temperature, pulse, respiration rate. drop...

10.1007/s00436-025-08459-3 article EN cc-by-nc-nd Parasitology Research 2025-02-01

Nephrotic syndrome, a primarily paediatric disease, is associated with high relapse rate. Studies have reported behavioral and psychological difficulties in children nephrotic their caregivers siblings, factor that likely to influence the overall outcome of disease an adverse manner. In clinical practice, however, psychosocial aspects care may be overlooked pressure treat process, unless importance stressed by appropriate evidence.The study aims assess prevalence behavior abnormalities...

10.4103/0019-5545.49452 article EN cc-by-nc-sa Indian Journal of Psychiatry 2009-01-01

Here, we report the therapeutic potential of a natural quinazoline derivative (2-chloro-6-phenyl-8H-quinazolino[4,3-b]quinazolin-8-one) isolated from marine sponge Hyrtios erectus against human breast cancer. The cytotoxicity compound was investigated on carcinoma cell line (MCF-7). Antiproliferative activity estimated by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. MTT assay showed significant inhibition MCF-7 cells viability with IC50 value 13.04 ± 1.03 µg/mL...

10.3390/md17120658 article EN cc-by Marine Drugs 2019-11-23

The aim of the present study was to isolate and characterize goat embryonic stem cell-like cells from in vitro produced embryos. Inner cell mass (ICM) were isolated either mechanically or by enzymatic digestion 150 blastocysts 35 hatched whereas 100 morulae used for blastomeres isolation mechanically. ICM derived cultured on a feeder layer. primary colony formation significantly higher (P < 0.01) (77.14%) than early/expanded (54%) morula (14%). When ICMs (90%) as well (66%) more when (60%...

10.1080/10495398.2011.622189 article EN Animal Biotechnology 2011-10-01

Abstract Cancer stem cells are known to be controlled by pathways that dormant in normal adult cells, for example, PTEN, which is a negative regulator of transcription factor STAT3. STAT3 regulates genes involved cell self-renewal and thus represents novel therapeutic target enormous clinical significance. Studies on breast cancer (BCSC) have been also significantly correlated with STATs. We describe here the first time strategy selectively CSCs induce downregulation downstream reducing...

10.1158/1535-7163.mct-17-0070 article EN Molecular Cancer Therapeutics 2017-11-15

Background and Objectives: Neonatal hypoglycemia, a common metabolic problem, often goes unnoticed owing to lack of specific symptoms. We designed this study assess the incidence hypoglycemia in healthy normal birth weight low babies, including both preterm small for gestational age (SGA) newborns, evaluate impact early breastfeeding on exclusive breast feeding glucose values up 48 h age. Design Settings: A hospital-based prospective longitudinal study. Materials Methods: The was conducted...

10.4103/0331-3131.92951 article EN Annals of Nigerian Medicine 2011-01-01

Domestic ducks are of paramount importance as a cheap source protein in rural India. Andaman local duck (ALD) is an indigenous avian genetic resource and Nicobar islands (ANI) mainly distributed Middle Northern parts these islands. Negligence has brought this breed on the edge extinction necessitating immediate conservation efforts. Here, we report diversity, population structure matrilineal root ALD. Partial mtDNA D-loop sequences were analyzed 71 ALD samples analysis revealed 19...

10.1371/journal.pone.0245138 article EN cc-by PLoS ONE 2021-02-09

Mothers and children are biologically related dependent. They should be considered as a single unit which is very important regarding adherence to anti-retroviral therapy (ART). Very high levels of required for effective ART. We therefore carried out this study examine the different factors associated with among human immunodeficiency virus (HIV)-positive mothers their HIV-positive receiving ART.A hospital-based cross-sectional study.Ninety-four 94 under ART attending center tertiary care...

10.4103/0019-5359.115733 article EN Indian Journal of Medical Sciences 2012-01-01

Abstract A study was conducted to determine the optimum dosage of exogenous cholesterol‐loaded cyclodextrins (CLC) get maximum cryoprotection for bubaline spermatozoa. In present study, 120 × 10 6 spermatozoa were incubated in 2, 3 and 4 mg CLC as grouped Gr II, III IV, respectively, sperm progressive motility, intracellular Ca 2+ , capacitation status by protein tyrosine phosphorylation (PTP) assay zona binding per cent (ZBP) cleavage rate (CR) cryopreserved buffalo vitro fertility assessed...

10.1111/rda.13674 article EN Reproduction in Domestic Animals 2020-03-17

Objectives The present study was conducted to detect the occurrence of β-lactamase and biofilm-producing Escherichia coli, Salmonella , Klebsiella in broilers native fowl reared Andaman Nicobar Islands, India. also included molecular docking experiments confirm nature catalytic domains found variants obtained reveal clonal relationship isolates with human clinical strains from database. Materials methods A total 199 cloacal swabs were collected five poultry breeds/varieties (broiler,...

10.3389/fvets.2022.1075133 article EN cc-by Frontiers in Veterinary Science 2023-01-05

The present study evaluates the effect of dietary zinc supplementation on reproductive and productive performance Teressa goat, an indigenous species ofAndaman Nicobar Islands.Eighteen female goats were randomly divided into 3 groups 6 animals each; (A) control with basal ration without any (B) Treatment 1 supplemented 50 ppm oxide (C) 2 100 oxide.Different parameters, e.g.numbers days to oestrus, incidence pregnancy rate, kidding rates weight kids recorded.Data indicated that different...

10.14202/vetworld.2014.380-383 article EN cc-by Veterinary World 2014-06-01

Objective: To investigate the effect of Moringa oleifera leaf extract on semen quality parameters in Teressa goat buck. Methods: A total 25 samples from six bucks were selected for study. Spermatozoa 150× 10 6 incubated 0, 300, 500 and 700 μg as group I, II, III IV, respectively. Liquid stored analysed motility, viability, sperm abnormalities, plasma membrane, acrosomal nuclear integrities, seminal intracellular enzymes [aspartate aminotransferase (AST), alanine (ALT) lactate dehydrogenase...

10.4103/apjr.apjr_159_23 article EN cc-by-nc-sa Asian Pacific Journal of Reproduction 2024-03-01

Aim: The present experiment was conducted to investigate and compare the haematological parameters of different pig breeds available at Andaman Nicobar Islands, India viz.Andaman wild pig, Nicobari desi Large White Yorkshire (LWY).Six erythrocyte traits, seven leukocyte traits four platelet were assessed.Materials Methods: 10 ml blood collected from each adult via external jugular vein aseptically in a collection tube containing anticoagulant EDTA (2 mg EDTA/ml blood).All these measured by...

10.14202/vetworld.2013.794-798 article EN cc-by Veterinary World 2013-08-28
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