A5005523985- Sodium Intake and Health
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Nutritional Studies and Diet
- Cardiovascular and exercise physiology
- Cardiovascular Effects of Exercise
- Exercise and Physiological Responses
- Heart Rate Variability and Autonomic Control
- Nutrition and Health in Aging
- Thermoregulation and physiological responses
- Sports Performance and Training
- Muscle metabolism and nutrition
- Diet and metabolism studies
- Cardiac Ischemia and Reperfusion
- Renal function and acid-base balance
- Adipose Tissue and Metabolism
- Cardiac Arrest and Resuscitation
- Sports injuries and prevention
- Cardiovascular Health and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Heat shock proteins research
- Peripheral Artery Disease Management
- Clinical Nutrition and Gastroenterology
- Climate Change and Health Impacts
- Antioxidant Activity and Oxidative Stress
University of Delaware
2017-2024
American College of Surgeons
2023
Bastyr University
2022
Christiana Care Health System
2018
Thomas Jefferson University
2018
Boston University
2004-2010
University Medical Center
2004-2010
Boston Medical Center
2004-2010
Shannon Applied Biotechnology Centre
2010
Tel Aviv University
2005
Section:ChooseTop of pageAbstract <<Question 1Question 2Question 3METHODSRESULTSDISCUSSIONReferencesCITING ARTICLES
OBJECTIVES: This investigation examined the effect of 6 months high‐ or low‐intensity resistance exercise on muscular strength and endurance stair climbing ability in adults aged 60 to 83. DESIGN: A randomized controlled trial. SETTING: University Florida Center for Exercise Science PARTICIPANTS: Sixty‐two men women completed study protocol. Subjects were matched randomly assigned a control (n = 16), (LEX, n 24), high‐intensity (HEX, 22) group. INTERVENTION: Six progressive, whole‐body...
Previous studies have indicated that patients with panic disorder are more likely than normal subjects to acute attacks during inhalation of CO2, but methodological objections been raised. In this study the authors attempted address three these problems by ensuring raters who assessed whether occurred were blind subjects' diagnoses, randomizing order administration 5% CO2 and hyperventilation, challenging a greater number 7% CO2.Patients underwent 20-minute inhalations 15 minutes room-air...
We examined the effects of 3 days exercise in a cold environment on expression left ventricular (LV) heat shock proteins (HSPs) and contractile performance during vivo ischemia-reperfusion (I/R). Sprague-Dawley rats were divided into following three groups ( n = 12/group): 1) control, 2) (60 min/day) at 4°C (E-Cold), 3) 25°C (E-Warm). Left anterior descending coronary occlusion was maintained for 20 min, followed by 30 min reperfusion. Compared with control group, both E-Cold E-Warm higher P...
Endurance exercise provides cardioprotection against ischemia-reperfusion (I/R) injury. Exercise-induced is associated with increases in cytoprotective proteins, including heat shock protein 72 (HSP72) and antioxidant enzyme activity. On the basis of reported half-life these putative cardioprotective we hypothesized that exercise-induced I/R injury would be lost within days after cessation exercise. To test this, male rats (4 mo) were randomly assigned to one five experimental groups: 1)....
Abstract It is well established that both short‐term (1–5 days) and long‐term (weeks to months) high intensity exercise (i.e. 70–75% V O 2max ) provides cardioprotection against ischaemia‐reperfusion injury. However, it unclear if moderate will also provide cardioprotection. Aim: Therefore, these experiments compared the protective effects of vs. in providing defense Methods: Male Sprague–Dawley rats were randomly assigned one three‐experimental groups: (1) sedentary (control); (2) treadmill...
Metalloproteinases (MMPs) are proteolytic enzymes that function in the extracellular matrix to degrade connective tissues. While it is clear exercise-induced injury skeletal muscle promotes increased expression of MMPs, relationship between exercise intensity and MMPs muscles unknown. These experiments tested hypothesis metalloproteinases (MMP-2 MMP-9) dose-dependent such high-intensity endurance increases MMP whereas low-intensity will not promote muscles. Female rats (4 months old)...
Myocyte contractile dysfunction occurs in pathological remodeling association with abnormalities calcium regulation. Mice cardiac myocyte-specific overexpression of Galphaq develop progressive left ventricular failure associated myocyte and dysregulation.
Aims: This study aimed to describe glucose variability (GV) and explore postprandial glycaemia the association with food composition following breakfast in children young people (CYP) type 1 diabetes (T1D). Methods: was an observational of CYP aged 1–17 years using continuous monitoring (CGM). Retrospective CGM data were collected assess GV along questionnaires about meal 4‐h period for 7 days. Statistical analysis included Student’s t ‐tests linear mixed models. Results: Ninety‐six...
Endurance exercise provides cardioprotection against ischemia-reperfusion-induced myocardial stunning and infarction. A recent study demonstrates that an exercise-induced increase in manganese superoxide dismutase (MnSOD) activity is essential to protect the heart It unknown if elevation cardiac MnSOD also a prerequisite achieve protection stunning. Therefore, this determined requirement Adult male rats remained sedentary or performed successive bouts of endurance exercise. Hearts were...
It has previously been shown that high dietary salt impairs vascular function independent of changes in blood pressure. Rodent studies suggest NADPH-derived reactive oxygen species mediate the deleterious effect on vasculature, and here we translate these findings to humans. Twenty-nine healthy adults (34 ± 2 yr) participated a controlled feeding study. Participants completed 7 days low-sodium diet (LS; 20 mmol sodium/day) high-sodium (HS; 300 random order. All participants were resistant,...
The influence of dietary sodium and potassium on blood pressure (BP) has been extensively studied, however their impact endothelial function, particularly any interactive effects, received less attention. purpose this study was to determine if can offset the deleterious effect high function independent BP. Thirty-three adults with salt-resistant BP (16 M 17 F; 27 ± 1 year) completed seven days each following diets in a random order: moderate potassium/low diet (65 mmol potassium/50 sodium;...
Sports participation confers many health benefits yet greatly increases injury risk. Long-term outcomes in former athletes and transition to life after competitive sports are understudied. Ending a sport may pose physical psychosocial challenges. The purpose was determine the lived experiences of how their impacted long-term well-being. Former college varsity participated semistructured interviews focusing on experiences, including past current health, impact injuries, activity, exercise,...
The interaction of substrates and hormones in response to ingestion intact proteins during endurance exercise is unknown. This study characterized substrate hormone responses supplementation exercise. Nine male runners participated 3 trials which a non-fat (MILK), carbohydrate (CHO), or placebo (PLA) drink was consumed 2-hour treadmill >· run at 65% V̇O 2max . Circulating levels insulin, glucagon, epinephrine, norepi-nephrine, growth hormone, testosterone, cortisol were measured. Plasma...
Abstract Objective We recently demonstrated ETB R mediate vasodilation in young but not postmenopausal women; it is unclear if this related to age or a decline ovarian hormones. The purpose of study was test the hypothesis that responses are modulated by Methods measured cutaneous vasodilatory 12 women (22 ± 1 years, 23 kg/m 2 ) during ML (days 20‐25) and EF 2‐5) phases menstrual cycle. Cutaneous microdialysis perfusions lactated Ringer (control), antagonist ( BQ ‐788, 300 nmol/L), ETA ‐123,...