- Parasites and Host Interactions
- Global Maternal and Child Health
- SARS-CoV-2 detection and testing
- Adrenal Hormones and Disorders
- HIV Research and Treatment
- vaccines and immunoinformatics approaches
- Chronic Kidney Disease and Diabetes
- COVID-19 Clinical Research Studies
- Diabetes and associated disorders
- Polyomavirus and related diseases
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Autoimmune Neurological Disorders and Treatments
- Histiocytic Disorders and Treatments
- HIV/AIDS Research and Interventions
- Research on Leishmaniasis Studies
- Tuberous Sclerosis Complex Research
- Vitamin C and Antioxidants Research
- Infectious Encephalopathies and Encephalitis
- Global Health and Surgery
- Acute Kidney Injury Research
- SARS-CoV-2 and COVID-19 Research
- Alcoholism and Thiamine Deficiency
Rwanda Zambia HIV Research Group
2021-2025
Centre for Infectious Disease Research in Zambia
2024
Emory University
2022
We evaluated changes in female genital schistosomiasis (FGS) 6 to 12 months after praziquantel treatment among 43 adult Zambian women. Most women (60%) experienced decreased FGS severity and 23% complete lesion resolution. This is the first study demonstrate a meaningful effect of
Tuberous sclerosis complex (TSC) is a rare multisystemic neurocutaneous syndrome with wide spectrum of clinical manifestations. We present case 14-year-old adolescent female who presented history facial angiofibromas since the age 8 months. Physical examination was remarkable for multiple on face, and other cutaneous manifestations TSC. MRI head, abdomen revealed cortical tubers, bilateral periventricular subependymal nodular lesions, calcifications, kidney enlargement renal angiomyolipomas...
Background The World Health Organization estimates that 56 million women and girls live with female genital schistosomiasis (FGS) in sub-Saharan Africa. FGS is often confused symptoms of other abnormalities, gold standard diagnosis colposcopy infeasible most health facilities. Schistosomiasis haematobium endemic Zambia, yet routine screening or diagnostic efforts for remain unavailable. Our study aimed to develop pilot test a feasible algorithm implement Zambian government clinics....
Background: The world needs an effective HIV-1/AIDS vaccine. Even in the broader context of antiretroviral treatment and prevention, a vaccine remains best solution likely key component any package truly ending AIDS epidemic. Vaccine is particularly needed most affected regions like sub-Saharan Africa, where HIV-1 significantly impacts people's lives economy.Methods: CD8+ killer T cells impose selective pressure on their protective potential should be utilized for vaccination. Our program...
Niacin or tryptophan deficiency causes pellagra. Isoniazid interferes with the absorption of niacin and individuals on (INH) are at risk preventive therapy (IPT) is administration isoniazid to immunosuppressed prevent active tuberculosis (TB). IPT, in sub-Saharan Africa, region worst hit by HIV a high TB prevalence, recommended. A 40-year-old, HIV+ Zambian woman Antiretroviral for five years IPT three months presented four-day history constipation, generalised body weakness irrelevant talk....
Autoimmune polyglandular syndromes (APS) are rare autoimmune endocrinopathies characterized by the coexistence of at least two endocrine gland insufficiencies developed from mechanisms. APS may also be associated with non-endocrine immune diseases. In HIV infection, antiretroviral therapy can improve quality life to reduce incidence opportunistic infections, malignancies, and death. disease complications, such as reconstitution inflammatory syndrome (IRIS) presenting malignancies or We here...
Contrast-associated acute kidney injury (CAAKI) is defined as (AKI) occurring within 72 hours of administration contrast media (CM) and linked to adverse outcomes including longer hospital stay, increased mortality, a higher risk chronic disease in later life. Risk factors for the development CAAKI Zambian pediatric population have not been well studied.The objective this study was assess burden CAAKI, ascertain its factors, describe short-term hospitalized children at University Teaching...