A5036734727- Probiotics and Fermented Foods
- Antimicrobial Peptides and Activities
- Gut microbiota and health
- Microbial Metabolites in Food Biotechnology
- Enzyme Production and Characterization
- Plant Pathogenic Bacteria Studies
- Viral gastroenteritis research and epidemiology
- Protein Hydrolysis and Bioactive Peptides
- Biochemical Acid Research Studies
- Plant tissue culture and regeneration
- Biochemical and Structural Characterization
- Animal Virus Infections Studies
- Peroxisome Proliferator-Activated Receptors
- Advanced MRI Techniques and Applications
- Characterization and Applications of Magnetic Nanoparticles
- Viral Infections and Immunology Research
- Vagus Nerve Stimulation Research
- Plant Virus Research Studies
- Plant Pathogens and Fungal Diseases
- Magnetic and Electromagnetic Effects
- Virus-based gene therapy research
- Nuclear Physics and Applications
- Animal Disease Management and Epidemiology
- Macrophage Migration Inhibitory Factor
- Oral microbiology and periodontitis research
Institute for Basic Science
2022-2023
Yonsei University
2022
California Institute of Technology
2022
Seoul National University
2018-2021
Norgen Biotek Corporation (Canada)
2008
Julius Kühn-Institut
2008
Max Planck Society
2004
Synbiotics, which are the combination of probiotics and prebiotics, have recently attracted attention because their synergistic net health benefits. Probiotics been used as alternatives to antibiotics. Among probiotics, Lactobacillus plantarum (LP) has shown strong antimicrobial activity against Escherichia coli K99, a major livestock pathogen. In this study, we aimed investigate phthalyl pullulan nanoparticle (PPN)-treated LP. Interestingly, when PPNs were added LP, internalized into LP...
Measuring cellular and tissue mechanics inside intact living organisms is essential for interrogating the roles of force in physiological disease processes. Current agents studying mechanobiology intact, are limited by poor light penetration material stability. Magnetomotive ultrasound an emerging modality real-time vivo imaging mechanics. Nonetheless, it has sensitivity spatiotemporal resolution. Here we describe magneto-gas vesicles (MGVs), protein nanostructures based on gas magnetic...
One of the most challenging aspects probiotics as a replacement for antibiotics is to enhance their antimicrobial activity against pathogens. Given that prebiotics stimulate growth and/or probiotics, we developed phthalyl inulin nanoparticles (PINs) and observed effects on cellular activities Pediococcus acidilactici (PA). First, assessed internalization PINs into PA. The was largely regulated by glucose transporters in PA, process energy-dependent. Once internalized, induced PA produce...
Abstract Fire blight caused by Erwinia amylovora is the most destructive bacterial disease of pear and apple. The goal this research was to improve fire resistance apple transformation with a gene encoding for an extracellular polysaccharide (EPS)‐depolymerase from E. phage phi‐Ea1h. EPS‐depolymerase ( dpo ) driven constitutive promoter CaMV35S transferred into scion cv. ‘Pinova’ through Agrobacterium tumefaciens ‐mediated leaf disk using binary vector strains EHA105 or LBA4404. integration...
Aim of the studyEffect internalized phthalyl starch nanoparticles (PSNs) on antimicrobial ability Lactococcus lactis (LL) KCTC 2013.
A new formulation, nanoprebiotics [e.g., phthalyl pullulan nanoparticles (PPNs)], was demonstrated to enhance the antimicrobial activity of probiotics Lactobacillus plantarum (LP)] in vitro through intracellular stimulation better than that by backbone prebiotics, which are commonly used. In this study, we aimed investigate whether combination would exert distinct effects as synbiotics vivo . Synbiotics combinations LP, pullulan, and PPNs were used experimental treatments a dysbiosis-induced...
The evaluation of host‐plant susceptibility to Erwinia amylovora and colonization tissue by individual strains was facilitated labelling the pathogen with green fluorescent protein (GFP). Colonization apple leaves assayed a fluorescence microscope associated visual disease ratings on plants describe virulence (= aggressiveness) fireblight pathogen. Resistance induced 2,6‐dichloro‐isonicotinic acid (INA) benzo(1,2,3‐) thiadiazol‐7‐carbothioic acid‐S‐methyl ester (BTH, active component BION™)...
Abstract Measuring cellular and tissue mechanics inside intact living organisms is essential for interrogating the roles of force in physiological disease processes, a major goal field mechanobiology. However, existing biosensors 3D mechanics, primarily based on fluorescent emissions deformable materials, are limited vivo measurement due to light penetration poor material stability intact, organisms. While magneto-motive ultrasound (MMUS), which uses superparamagnetic nanoparticles as...
Porcine epidemic diarrhea (PED) is a highly contagious enteric swine disease. The large economic impact of PED on the industry worldwide has made development an effective vaccine necessity. S0, truncated region porcine virus (PEDV) spike protein, been suggested as candidate antigen for subunit vaccines; however, poor solubility problems when protein expressed in Escherichia coli, and inherent vaccines, such low immunogenicity, remain. Flagellin widely used fusion partner to enhance...
Abstract Background : In our previous study, it was demonstrated that nanoprebiotics, phthalyl pullulan nanoparticles (PPNs), a new formulation enhanced the antimicrobial activity of probiotics Lactobacillus plantarum (LP) in vitro by intracellular stimulation more than backbone prebiotics generally used far. this we aimed to investigate whether combination may exert distinguished effect as synbiotics vivo . To accomplish goal, LP, pullulan, and PPNs were treated dysbiosis-induced mouse...